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Part Description

LP16650-1   Histoplasma capsulatum
Histoplasmosis capsulatum is a dimorphic fungal pathogen with filamentous or yeast forms,depending on nutritional factors and temperature.The M antigen is a well-known glycoprotein used as a diagnostic antigen for acute histoplasmosis as it induces the first precipitins during disease. Monoclonal antibodies (mAbs) to the M antigen have been found to modify the pathogenesis of histoplasmosis.Given the shortcomings of current therapies, the administration of mAbs is being investigated. PMID: 22347215 The H band is less commonly seen than the M band and is indicative of chronic or severe acute infections with H capsulatum.

H. capsulatum is found in nature primarily as a saprophytic mold. The mold form is comprised of hyaline septate hyphae, which produce two different asexual reproduction structures, macroconidia and microconidia. The micronidia are believed to be responsible for disease propagation since their 2-6 µm size is well suited for disposition into the distal alveoli. Infection is typically acquired through inhalation of fungal propagules upon disturbances of contaminated soil or excreta. Environmental and genetic factors influence disease manifestations which can range from asymptomatic or mild influenza-like disease to a disseminated sepsis form. Manifestations depend on the magnitude of exposure, the host's immunological status and the virulence of the infective strain. Reactivation of latent infection can result in significant disease, particularly for immunosuppressed individuals. Despite the availability of potent antifungal drugs, nearly one in ten patients hospitalized with histoplasmosis dies. PMID: 17223625 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Histoplasma capsulatum Ab.IgM^1st specimen:Titr:Pt:CSF:SemiQn:
Long Common Name
Histoplasma capsulatum IgM Ab [Titer] in Cerebrospinal Fluid --1st specimen
Short Name
H capsul IgM sp1 Titr CSF
Display Name
H. capsulatum IgM spec 1 (CSF) [Titer]
Consumer Name Alpha Get Info
Histoplasma capsulatum IgM antibody specimen 1, Spinal fluid

Part Model Get Info

  • Component
    Histoplasma capsulatum Ab.IgM^1st specimen
    LP308354-2
    • Analyte
      Histoplasma capsulatum Ab.IgM
      LP38408-8
      • Component Numerator
        Histoplasma capsulatum Ab.IgM
        LP38408-8
        • Component Numerator Core
          Histoplasma capsulatum
          LP16650-1
        • Component Numerator Core Suffix
          Ab.IgM
          LP32403-5
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      1st specimen
      LP20166-2
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Titr
    LP6881-9
  • Time
    Pt
    LP6960-1
  • System
    CSF
    LP7156-5
    • System Core
      CSF
      LP7156-5
    • Super System
      NULL
       
  • Scale
    SemiQn
    LP436123-6
  • Method
    NULL
     

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.15
Last Updated
Version 2.83 (MIN)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Histoplasma capsulatum Ab.IgM^Vzorek 1:Arbitrární koncentrace (titr):Časový bod:Mozkomíšní mok:Semikvantitativní:
el-GRGreek (Greece)Histoplasma capsulatum (Ιστόπλασμα) Αντισώματα IgM^1ο δείγμα:Titr:Pt:ΕΝΥ:Ημιποσοτική:
Synonyms: 1ο δείγμα Histoplasma capsulatum (Ιστόπλασμα) MICRO Pt Titr Ανοσοσφαιρίνη M Αντίσωμα Αντισώματα IgM ΕΝΥ Ημιποσοτική
es-ESSpanish (Spain)Histoplasma capsulatum IgM^1er especimen:Titulo / Factor de dilución:Punto temporal:Líquido Cefalorraquideo:Semicuantitativo:
Synonyms: Semicuantitativo
es-MXSpanish (Mexico)Histoplasma capsulatum Ab.IgM ^1er espécimen:Título:Punto temporal:Fluído espinal cerebral:Cuantitativo:
fr-FRFrench (France)Histoplasma capsulatum Ac IgM^1er prélèvement:Titre:Ponctuel:Liquide céphalorachidien:Semi-Quantitatif:
fr-CAFrench (Canada)Histoplasma capsulatum, IgM^1er échantillon:Titre:Temps ponctuel:LCR:SemiQn:
it-ITItalian (Italy)Histoplasma capsulatum Ab.IgM^1° campione:Titr:Pt:LCS:SemiQn:
Synonyms: Anticorpi IgM anticorpo Liquido cerebrospinale Microbiologia Punto nel tempo (episodio) Titolo
ko-KRKorean (Korea, Republic Of)히스토플라스마 캡슐라툼 항체.면역글로불린 M^제1 검체:역가:검사시점:뇌척수액:정량:
nl-NLDutch (Netherlands)Histoplasma capsulatum As.IgM^1ste monster:titer:moment:liquor cerebrospinalis:semikwantitatief:
Synonyms: antistof; antilichaam
pt-BRPortuguese (Brazil)Histoplasma capsulatum Ac.IgM^1ª amostra:Título:Pt:LCR:Qn:
Synonyms: Immune globulin M; Immunoglobulin M; H capsul; H capsulatum; H farciminosum; Histoplasma farciminosum; sp1; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Cerebral spinal fluid; Spinal Fluid; Cerebrospinal Fl; Spinal Flu; Spinal Fld; Quantitative; QNT; Quant; Quan; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Spec; Pre immunization; Acute specimen; Histo; Histopl; Histoplasmos; Histoplasmosis; First; Microbiology
zh-CNChinese (China)荚膜组织胞浆菌 抗体.IgM^第1个标本:滴定度:时间点:脑脊液:半定量型:
Synonyms: Ab.IgM;IgM;抗体 IgM Ab;自身抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 免疫之前 免疫之前的标本 免疫前 免疫前标本 免疫球蛋白 M 受检物 在免疫之前 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 急性期 急性期标本 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 标本（样本、样品、试样） 样品 样本 皮疽组织胞浆菌 Ab 皮疽组织胞浆菌 Ab.IgM 皮疽组织胞浆菌;美洲型组织胞浆菌;鼻疽性组织浆菌 皮疽组织胞浆菌抗体 皮疽组织胞浆菌抗体.IgM 第1个标本（样本、样品、试样） 第一个标本 组织胞浆菌属 组织胞浆菌病 美洲型组织胞浆菌 Ab 美洲型组织胞浆菌 Ab.IgM 美洲型组织胞浆菌抗体 美洲型组织胞浆菌抗体.IgM 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 荚膜组织胞浆菌 Ab 荚膜组织胞浆菌 Ab.IgM 荚膜组织胞浆菌 IgM 试样 鼻疽性组织浆菌 Ab 鼻疽性组织浆菌 Ab.IgM 鼻疽性组织浆菌抗体 鼻疽性组织浆菌抗体.IgM

Example Units

UnitSource
{titer}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=40773-4