40824-5

von Willebrand factor (vWf) cleaving protease inhibitor [Units/volume] in Platelet poor plasma

Active

Part Description

LP32459-7 von Willebrand factor cleaving protease inhibitor
von Willebrand factor (vWF) cleaving protease, or ADAMTS13, is a metalloprotease that cleaves vWF and thereby limits platelet aggregation and formation of microthrombi. vWF cleaving protease inhibitors can decrease the protease activity and/or more rapidly remove the enzyme from the circulation. Such inhibitors are one cause of thrombotic thrombocytopenic purpura (TTP), a disorder characterized by thrombocytopenia, anemia, fever, and neurologic and renal abnormalities. Idiopathic TTP is often due to anti-ADAMTS13 autoantibodies, while inherited TTP is an autosomal recessive disorder due to mutations in the ADAMTS13 gene that lead to impaired protease function. Work-up of patients with TTP can include vWF cleaving protease activity and, if that activity is low, inhibitor screen followed by quantification. PMID: 18756543 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: von Willebrand factor cleaving protease inhibitor:ACnc:Pt:PPP:Qn:
Long Common Name: von Willebrand factor (vWf) cleaving protease inhibitor [Units/volume] in Platelet poor plasma
Short Name: vWF Cp Inhib PPP-aCnc
Display Name: vWf cleaving protease inhibitor Qn (PPP)
Consumer Name Alpha Get Info: vWf cleaving protease inhibitor, Blood

Part Model Get Info

Component
von Willebrand factor cleaving protease inhibitor
LP32459-7
- Analyte
  von Willebrand factor cleaving protease inhibitor
  LP32459-7
  - Component Numerator
    von Willebrand factor cleaving protease inhibitor
    LP32459-7
    - Component Numerator Core
      von Willebrand factor cleaving protease inhibitor
      LP32459-7
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
ACnc
LP6773-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
PPP
LP7494-0
- System Core
  PPP
  LP7494-0
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: COAG
Type: Laboratory
First Released: Version 2.15
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 8839

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	von Willebrandův faktor (vWf) štěpící proteáza inhibitor:Arbitrární koncentrace:Časový bod:Plazma chudá na trombocyty:Kvantitativní:
de-AT	German (Austria)	Synonyms: ADAMTS 13 Inhibitor
de-DE	German (Germany)	von-Willebrand-Faktor-spaltende-Protease-Inhibitor:Arbiträre Konzentration:Zeitpunkt:Thrombozytenarmes Plasma:Quantitativ:
el-GR	Greek (Greece)	αναστολέας πρωτεάσης διάσπασης παράγοντα Von Willebrand:ACnc:Pt:PPP:Qn: Synonyms: ACnc COAG PPP Pt Qn αναστολέας πρωτεάσης διάσπασης παράγοντα Von Willebrand παράγοντας Von Willebrand πρωτεάση διάσπασης παράγοντα Von Willebrand
es-ES	Spanish (Spain)	Inhibidor de la proteasa divisora del Factor de von Villebrand:Concentración arbitraria:Punto temporal:Plasma pobre en plaquetas:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Inhibidor de la proteasa que escinde el factor von Willebrand:Concentración arbitraria:Punto temporal:Plasma pobre en plaquetas:Cuantitativo:
fr-CA	French (Canada)	Inhibiteur de la protéase clivage du Facteur von Willebrand:Concentration arbitraire:Temps ponctuel:Plasma pauvre en plaquettes:Quantitatif:
fr-FR	French (France)	Facteur Willebrand inhibiteur de la protéase:Arbitraire/Volume:Ponctuel:Plasma pauvre en plaquettes:Numérique:
fr-BE	French (Belgium)	Inhibiteur de la protéase de coupage Facteur von Willebrand:Concentration arbitraire:Temps ponctuel:Plasma pauvre en plaquettes:Quantitatif: Synonyms: Fvw
it-IT	Italian (Italy)	von Willebrand, inibitore proteasi di taglio fattore:ACnc:Pt:PPP:Qn: Synonyms: Concentrazione Arbitraria Fattore di von Willebrand (vWf) Inibitore di proteasi di taglio del fattore di von Plasma povero di piastrine Proteasi di taglio del fattore di von Willebrand Punto nel tempo (episodio) Studio di coagulazione
ko-KR	Korean (Korea, Republic Of)	폰 빌레브란트 인자 절단 단백분해효소 억제인자:임의농도:검사시점:혈소판제거혈장:정량:
nl-NL	Dutch (Netherlands)	von Willebrand-factor cleaving protease inhibitor:eenheid/volume:moment:plaatjesarm plasma:kwantitatief: Synonyms: coagulatiemethode
pl-PL	Polish (Poland)	Inhibitor proteazy rozkładającej czynnik von Willebranda:stężenie w jednostkach umownych:punkt w czasie:osocze ubogopłytkowe:ilościowy: Synonyms: ADAMTS13 Czynnik von Willebranda (vWf) Inhibitor ADAMTS13 PPP
pt-BR	Portuguese (Brazil)	Fator de von Willebrand clivagem do inibidor de protease:ACnc:Pt:PPPQ:Qn: Synonyms: ; vWF Cp Inhib; ADAMTS13 inhibitor; vWCP; VWF-cp; VWFCP; vWf; Arbitrary concentration; Point in time; Random; Platelet poor plasma; Plas; Quantitative; QNT; Quant; Quan; Vonwillebrand; Von will; PR; Inhibit; Fac; Fact; COAGULATION
ru-RU	Russian (Russian Federation)	von Willebrand (vWf) расщепляющая протеаза ингибитор:ПроизвКонц:ТчкВрм:ОПП:Колич: Synonyms: Количественный Обеднённая пластинками плазма;Бедная тромбоцитами плазма Произвольная концентрация Точка во времени;Момент
tr-TR	Turkish (Turkey)	von Willebrand faktörü parçalıyıcı proteaz inhibitörü:SçKons:Zmlı:TFkP:Kant:
uk-UA	Ukrainian (Ukraine)	інгібітор протеази, що розщеплює Фактор фон Віллебранда:Довільна Концентрація:МоментЧасу:Бідна тромбоцитами плазма:Кількісно: Synonyms: ADAMTS13; ADAMTS-13; ADAMTS13 inhibitor; Arbitrary concentration; COAGULATION; Fac; Fact; Hematology; Heme; Inhib; Inhibit; Plas; Platelet poor plasma; Point in time; PR; QNT; Quan; Quant; Quantitative; Random; TTP; Von will; Vonwillebrand; vWCP; vWf; vWF Cp; vWF Cp Inhib; VWFCP; VWF-cp
zh-CN	Chinese (China)	von Willebrand 因子裂解蛋白酶抑制剂:任意型浓度:时间点:贫血小板血浆:定量型: Synonyms: von Willebrand von Willebrand 因子（von Willebrand Factor，vWf）;vWf;vWf 因子;血管性假血友病因子;血管性血友病因子 von Willebrand 因子（vWf 因子、血管性假血友病因子、血管性血友病因子）裂解蛋白酶;ADAMTS13;von Willebrand 因子裂解蛋白酶（von Willebrand Factor Cleaving Protease，VWF-cp）;von Willebrand 因子裂解酶;vWCP;vWf 因子裂解蛋白酶;vWf 因子裂解酶;vWf 裂解酶;VWFCP;VWF-cp;血管性血友病因子裂解蛋白酶;血管性血友病因子裂解酶 von Willebrand 因子（vWf 因子、血管性假血友病因子、血管性血友病因子）裂解蛋白酶抑制剂;ADAMTS13 抑制剂;von Willebrand 因子裂解酶抑制剂;vWf 因子裂解蛋白酶抑制剂;vWf 因子裂解酶抑制剂;vWf 裂解蛋白酶抑制剂;vWf 裂解酶抑制剂;血管性血友病因子裂解蛋白酶抑制剂;血管性血友病因子裂解酶抑制剂乏血小板血浆;Platelet poor plasma;PPP 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度冯·威勒布兰德冯威勒布兰德冯威勒布兰德氏凝血功能;凝血功能试验;凝血过程;血液凝固;血液凝固功能;血液凝固过程可用数量表示的;定量性;数值型;数量型;连续数值型标尺因素抑制因子抑制物抑制物质时刻;随机;随意;瞬间朊酶系数蛋白质酵素

Example Units

Unit	Source
Inhibitor Units	REGENSTRIEF
[arb'U]/mL	Example UCUM Units

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.