41228-8
Xanthine [Presence] in Serum
Active
Part Descriptions
LP15953-0 Xanthine
A purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being formed by oxidation of hypoxanthine. The methylated xanthine compounds caffeine, theobromine, and theophylline and their derivatives are used in medicine for their bronchodilator effects. (Dorland, 28th ed)
Source: National Library of Medicine, MeSH 2006
LP15953-0 Xanthine
Xanthine is a product on the pathway of purine degradation and is converted to uric acid by the action of the xanthine oxidase (xanthine dehydrogenase) enzyme. Some people lack sufficient xanthine oxidase, and thus xanthine cannot be converted to uric acid. This rare genetic disorder is called xanthinuria results from excessive excretion of xanthine into the urine. This disorder can result in urolithiasis and sometimes myopathy from xanthine deposition. Elevated xanthine can also result from allopurinol treatment. Xanthine is also the core chemical component of a group of alkaloids that are commonly used for their effects as mild stimulants and as bronchodilators, notably in treating the symptoms of asthma. Their effects, however, are widespread and their therapeutic range is narrow and so they are not the drug of choice in asthma treatment. Methylated xanthine derivatives include caffeine, theophylline, and theobromine (found mainly in chocolate). These drugs inhibit phosphodiesterase and antagonise adenoine.
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Xanthine:
PrThr: Pt: Ser: Ord: - Long Common Name
- Xanthine [Presence] in Serum
- Short Name
- Xanthine Ser Ql
- Display Name
- Xanthine Ql (S)
- Consumer Name Alpha Get Info
- Xanthine, Blood
Part Model Get Info
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.15
- Last Updated
- Version 2.56 (MIN)
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Xanthin: |
| el-GR | Greek (Greece) | Ξανθίνη: Synonyms: CHEM Ord PrThr Pt Ξανθίνη Ορός |
| es-ES | Spanish (Spain) | Xantina: |
| es-MX | Spanish (Mexico) | Xantina: |
| et-EE | Estonian (Estonia) | Ksantiin: Synonyms: Järgarvuline Juhuslik Seerum |
| fr-CA | French (Canada) | Xanthine: |
| fr-FR | French (France) | Xanthine: |
| fr-BE | French (Belgium) | Xanthine: |
| it-IT | Italian (Italy) | Xantina: Synonyms: Chimica Presenza o Soglia Punto nel tempo (episodio) Siero |
| ko-KR | Korean (Korea, Republic Of) | 크산틴: |
| nl-NL | Dutch (Netherlands) | xanthine: |
| pt-BR | Portuguese (Brazil) | Xantina: Synonyms: Arbitrary concentration; |
| ru-RU | Russian (Russian Federation) | Ксантин: Synonyms: Порядковый Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | Ksantin: Synonyms: Mevcut |
| zh-CN | Chinese (China) | 黄嘌呤: Synonyms: 2,6-二羟基嘌呤; |
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LOINC Copyright
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