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Part Descriptions

LP36423-9   Ganglioside GM1
Gangliosides are a family of molecules that are present throughout the body but especially prevalent in cells of the nervous system. Specific gangliosides are named for the carbohydrate sequence they contain and have a unique distribution within the nervous system. The oligosaccharide groups on gangliosides act as cell surface markers that play a role in cellular recognition and cell-to-cell communication, and they also act as specific receptors for certain pituitary glycoprotein hormones and certain bacterial protein toxins such as cholera toxin.
Anti-ganglioside antibodies, primarily IgG, are present in the sera from approximately 60% of patients with Guillain-Barré syndrome (GBS), and antibodies against different gangliosides are associated with different forms of GBS.
1. Antibodies against GD1a/GD1b and GD1b/GT1b complexes have been found in patients with more severe GBS requiring mechanical ventilation;
2. Antibodies against GM1 or those against GalNAc-GD1a have been associated with acute motor axonal neuropathy;
3. Anti-GQ1b antibodies are specifically associated with a variant of GBS called Fisher syndrome, which is characterized by ophthalmoplegia and ataxia.
Detection of specific markers early in the course of GBS may help guide the plan of care. PMID: 21214559 Source: Regenstrief LOINC, PMID: 2121455

LP38226-4   Ganglioside GM1 Ab
Ganglioside antibodies are associated with diverse peripheral neuropathies. Elevated antibody levels to ganglioside-monosialic acid (GM1) are associated with motor or sensorimotor neuropathies, particularly multifocal motor neuropathy. Anti-GM1 may occur as IgM (polyclonal or monoclonal) or IgG antibodies. These antibodies may also be found in patients with diverse connective tissue diseases as well as normal individuals. Source: ARUP Laboratories, GM1

LP222219-0   Ganglioside
A ganglioside molecule consists of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acid residues linked to the sugar chain. Molecules with one sialic acid residue are called monosialogangliosides (GM), those with two are called disialogangliosides (GD), and those with three are trisialogangliosides (GT). Gangliosides without any sialic acid residues are called asialogangliosides, while those that do not have a ceramide N-acyl group are called lysogangliosides. The number that typically is included at the end of the name indicates the order in which the molecule was discovered. For example, GM2 is a ganglioside with one sialic acid residue that was the second GM to be identified. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Ganglioside GM1 Ab:Titr:Pt:Ser:SemiQn:
Long Common Name
Ganglioside GM1 Ab [Titer] in Serum
Short Name
GM1 Gangl Ab Titr Ser
Display Name
Ganglioside GM1 Ab (S) [Titer]
Consumer Name Alpha Get Info
Ganglioside GM1 antibody, Blood

Part Model Get Info

  • Component
    Ganglioside GM1 Ab
    LP38226-4
    • Analyte
      Ganglioside GM1 Ab
      LP38226-4
      • Component Numerator
        Ganglioside GM1 Ab
        LP38226-4
        • Component Numerator Core
          Ganglioside GM1
          LP36423-9
        • Component Numerator Core Suffix
          Ab
          LP20667-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Titr
    LP6881-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    SemiQn
    LP436123-6
  • Method
    NULL
     

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.16
Last Updated
Version 2.75 (MAJ)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Gangliosid GM1 Ab:Arbitrární koncentrace (titr):Časový bod:Sérum:Semikvantitativní:
el-GRGreek (Greece)Γαγγλιοσίδη GM1 Αντίσωμα:Titr:Pt:Ορός:Ημιποσοτική:
Synonyms: Pt SERO Titr Αντίσωμα Γαγγλιοσίδη Γαγγλιοσίδη GM1 Ημιποσοτική Ορός
es-MXSpanish (Mexico)Gangliósido GM1 Ab:Título:Punto temporal:Suero:Cuantitativo:
es-ESSpanish (Spain)Gangliósido GM1 Anticuerpos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:
Synonyms: Semicuantitativo
fr-FRFrench (France)Ganglioside GM1 Ac:Titre:Ponctuel:Sérum:Semi-Quantitatif:
fr-CAFrench (Canada)Ganglioside GM1, Ac:Titre:Temps ponctuel:Sérum:SemiQn:
it-ITItalian (Italy)Ganglioside GM1 Ab:Titr:Pt:Siero:SemiQn:
Synonyms: anticorpo Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant Titolo
ko-KRKorean (Korea, Republic Of)Monosialoganglioside GM1 Antibody:역가:검사시점:혈청:정량:
nl-NLDutch (Netherlands)ganglioside GM1 As:titer:moment:serum:semikwantitatief:
Synonyms: antistof; antilichaam
pl-PLPolish (Poland)Gangliozyd GM1 Ab:miano:punkt w czasie:surowica:półilościowy:
Synonyms: Przeciwciała do gangliozydu GM1
pt-BRPortuguese (Brazil)Monosialogangliosídeo GM1 Ac:Título:Pt:Soro:Qn:
Synonyms: ; GM1 Monosialo; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Ganglioside monosialo; Serology
zh-CNChinese (China)神经节苷脂 GM1 抗体:滴定度:时间点:血清:半定量型:
Synonyms: Ab;自身抗体 GM1;神经节糖苷 GM1 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 神经节糖苷 神经节苷脂 GM1 Ab 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

UnitSource
titerREGENSTRIEF
{titer}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=42203-0