42254-3
Nuclear Ab [Presence] in Serum by Immunofluorescence
Active
Part Descriptions
LP16670-9 Nuclear
The nucleus of a cell contains the body's genetic material. It is the site of transcriptional regulation, RNA processing and DNA synthesis and transcription.
PMID: 24563360
Source: Regenstrief LOINC
LP20752-9 Nuclear Ab
Anti-nuclear antibodies (ANAs), also known as anti-nuclear factor or ANF, are auto-antibodies directed against contents of the cell nucleus. They are present in low numbers in the general population but higher than normal amounts in autoimmune diseases, including lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, scleroderma, and autoimmune hepatitis.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Anti-nuclear antibodies
LP20752-9 Nuclear Ab
Anti-nuclear antibodies (ANAs, also known as anti-nuclear factor or ANF) are autoantibodies directed against contents of the cell nucleus. They are present in higher than normal numbers in autoimmune disease. The ANA test measures the pattern and amount of autoantibody which can attack the body's tissues as if they were foreign material. Autoantibodies are present in low titers in the general population, but in about 5% of the population, their concentration is increased, and about half of this 5% have an autoimmune disease.
The presence of ANA is indicative of lupus erythematosus (present in 80-90% of cases), though they also appear in some other auto-immune diseases such as[citation needed] Sjögren's syndrome (60%), rheumatoid arthritis (30-40%), autoimmune hepatitis, scleroderma and polymyositis & dermatomyositis (30%), and various non-rheumatological conditions associated with tissue damage. Other conditions with high ANA titre include Addison disease, Idiopathic thrombocytopenic purpura (ITP), Hashimoto's, Autoimmune hemolytic anemia, Type I diabetes mellitus, Mixed connective tissue disorder.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia, Wikipedia
Fully-Specified Name
- Component
- Nuclear Ab
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- IF
Additional Names
- Short Name
- ANA Ser Ql IF
- Display Name
- Nuclear Ab IF Ql (S)
- Consumer Name Alpha Get Info
- Nuclear antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.16
- Last Updated
- Version 2.73
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 700
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG4652-6 | Nuclear Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: ANA qual. IF |
de-DE | German (Germany) | Nukleärer Ak: |
es-ES | Spanish (Spain) | Nuclear Anticuerpos: |
es-MX | Spanish (Mexico) | Ab nuclear: |
et-EE | Estonian (Estonia) | Tuumavastased antikehad: Synonyms: Järgarvuline Juhuslik Seerum |
fr-CA | French (Canada) | Nucléaire, Ac: |
fr-FR | French (France) | Noyau anticorps: |
fr-BE | French (Belgium) | Nucléaire Ac: Synonyms: Anticorps |
it-IT | Italian (Italy) | Nucleare Ab: Synonyms: anticorpo Immunofluorescenza (IF) Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
ko-KR | Korean (Korea, Republic Of) | 핵 항체: |
nl-NL | Dutch (Netherlands) | nucleaire As: Synonyms: antistof; |
pl-PL | Polish (Poland) | Jądrowy Ab: Synonyms: Przeciwciała przeciwjądrowe |
pt-BR | Portuguese (Brazil) | Nuclear Ac: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Ядерный Ат: Synonyms: Антитело Иммунофлюоресценция (ИФ) Порядковый Сыворотка Точка во времени; |
tr-TR | Turkish (Turkey) | Nükleer Ab: Synonyms: Ak Çekirdek İmmünflorerans Mevcut |
zh-CN | Chinese (China) | 细胞核 抗体: Synonyms: Ab; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=42254-3
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright