42332-7
Alpha-1-Fetoprotein L3/Alpha-1-fetoprotein.total in Serum or Plasma
Active
Part Description
LP36040-1 Alpha-1-Fetoprotein.L3
In oncology, AFP-L3 is an isoform of Alpha-fetoprotein (AFP), a substance typically used in the triple test during pregnancy and for screening chronic liver disease patients for hepatocellular carcinoma (HCC). AFP can be fractionated by affinity electrophoresis into 3 glycoforms: L1, L2, and L3 based on the reactivity with the lectin Lens culinaris agglutinin (LCA). AFP-L3 binds strongly to LCA via an additional α 1-6 fucose residue attached at the reducing terminus of N-acetylglucosamine; this is in contrast to the L1 isoform. It is the L1 isoform which is typically associated with non-HCC inflammation of liver disease condition. The L3 isoform is specific to malignant tumors and its detected presence can serve to identify patients whom need increased monitoring for the development of HCC in high risk populations (i.e. chronic hepatitis B & C and/or liver cirrhosis). AFP-L3% is now being considered as a tumor marker for the North American demographic.
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Source: Wikipedia, Wikipedia
Fully-Specified Name
- Component
- Alpha-1-Fetoprotein.L3/Alpha-1-Fetoprotein.total
- Property
- MFr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- AFP L3 MFr SerPl
- Display Name
- AFP L3/Total AFP [Mass fraction]
- Consumer Name Alpha Get Info
- Alpha-fetoprotein L3/Total Alpha-1-fetoprotein, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.16
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 4468
Member of these Panels
LOINC | Long Common Name |
---|---|
96451-0 | Alpha-1-Fetoprotein and Alpha-1-Fetoprotein.L3 panel - Serum or Plasma |
96452-8 | Hepatocellular carcinoma risk panel - Serum or Plasma |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Alfa-1-fetoproteina L3/Alfa-1-fetoproteina.total: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Alfa-1-Fetoproteína.L3 / Alfa-1-Fetoproteína.total: |
et-EE | Estonian (Estonia) | Alfa-1-fetoproteiin.L3/alfa-1-fetoproteiin.üld: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
fr-CA | French (Canada) | Alpha-1-foetoprotéine.L3/Alpha-1-foetoprotéine.totale: |
fr-FR | French (France) | Alpha-1-foetoprotéine L3/alpha-1-foetoprotéine totale: |
fr-BE | French (Belgium) | Alpha-1-foetoprotéine.L3/Alpha-1-foetoprotéine.totale: Synonyms: AFP |
it-IT | Italian (Italy) | Alfa-1-Fetoproteina L3/Alfa-1-fetoproteina.totale: Synonyms: Alfa-1-Fetoproteina L3 Chimica Frazione di massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
ko-KR | Korean (Korea, Republic Of) | 알파-1-태아단백.L3/총알파-1-태아단백: |
nl-NL | Dutch (Netherlands) | alfa-1-foetoproteïne.L3/alfa-1-foetoproteïne.totaal: |
pt-BR | Portuguese (Brazil) | Alfa-1-Fetoproteína.L3/Alfa-1-Fetoproteína.total: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Альфа-1-Фетопротеин.L3/Альфа-1-фетопротеин.общий: Synonyms: Количественный Массовая доля Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | Alfa-1-Fetoprotein.L3/Alfa-1-fetoprotein.total: |
zh-CN | Chinese (China) | Alpha-1-胎儿球蛋白.L3/Alpha-1-胎儿球蛋白.总计: Synonyms: Ⅰ A1 型 A1 胎儿球蛋白 L3; |
Example Units
Unit | Source |
---|---|
% | Example UCUM Units |
% | REGENSTRIEF |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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