42618-9
Naloxone [Presence] in Urine by Screen method
Active
Part Description
LP28525-1 Naloxone
Naloxone is a pure opioid antagonist and, when taken at recommended doses, has no physiological effects in the absence of an opioid agonist. Intravenous naloxone becomes effective within two minutes of injection, but oral or sublingual naloxone has little effect due to its poor absorption. Therefore, intravenous naloxone is used to treat opioid overdose, and it is used as a sublingual combination with buprenorphine, an opioid agonist-antagonist used to treat chronic opioid-dependence, to lower buprenorphine's abuse potential as follows: when the combination is taken sublingually as prescribed, naloxone exerts little effect and buprenorphine's effects predominate; however, if crushed and injected intravenously, naloxone's antagonist properties reverse the agonist effects of buprenorphine and can precipitate withdrawal. PMID: 19368419 Nalaxone levels along with its inactive metabolite, naloxone-3-glucuronide (N3G), may be measured to monitor compliance or identify illicit opioid drug use.
Source: Regenstrief LOINC, PMID: 19368419
Fully-Specified Name
- Component
- Naloxone
- Property
- PrThr
- Time
- Pt
- System
- Urine
- Scale
- Ord
- Method
- Screen
Additional Names
- Short Name
- Naloxone Ur Ql Scn
- Display Name
- Naloxone Screen Ql (U)
- Consumer Name Alpha Get Info
- Naloxone, Urine
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.16
- Last Updated
- Version 2.73
- Change Reason
- The Property has been changed from ACnc to reflect new model for ordinal terms; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 9907
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 95796-9 | Opioids panel - Urine by Screen method |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG37627-3 | Naloxone| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Naloxona: |
| es-MX | Spanish (Mexico) | Naloxona: |
| fr-CA | French (Canada) | Naloxone: |
| fr-FR | French (France) | Naloxone: |
| fr-BE | French (Belgium) | Naloxone: |
| it-IT | Italian (Italy) | Naloxone: Synonyms: Livelli farmacologici e tossicologia Presenza o Soglia Punto nel tempo (episodio) Screening tossicologico |
| ko-KR | Korean (Korea, Republic Of) | 날록손: |
| nl-NL | Dutch (Netherlands) | naloxon: |
| pt-BR | Portuguese (Brazil) | Naloxone: Synonyms: Narcan; |
| ru-RU | Russian (Russian Federation) | Налоксон: Synonyms: Порядковый Токсикологический скрининг Точка во времени; |
| tr-TR | Turkish (Turkey) | Nalokzon: Synonyms: Mevcut |
| uk-UA | Ukrainian (Ukraine) | Налоксон: Synonyms: Addiction; |
| zh-CN | Chinese (China) | 钠洛酮: Synonyms: C19H21NO4; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=42618-9
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright