Version 2.80

Part Description

LP31707-0   Neuronal nuclear type 3
Neuronal nuclear type 3 Ab (ANNA-3) is one of three neuronal nuclear paraneoplastic antibodies that primarily binds to the nuclei of cerebellar Purkinje neurons and to renal glomerular podocytes. Symptoms of the presence of ANNA-3 include sensory or sensorimotor neuropathies, cerebellar ataxia, myelopathy, brain stem and limbic encephalopathy.It's presence in serum is most commonly indicative of a small-cell malignant tumor, most of which are primary tumors of the lung.Fluorescent staining patterns are used to distinguish ANNA-3 from the other two neuronal nuclear types, ANNA-1 and ANNA-2. ANNA-3 binds the nuclei of Purkinje neurons in the cerebellar cortex more than the molecular neurons, and does not bind granular neurons. ANNA-3 binds only the nuclei of indentate neurons, while ANNA-1 and ANNA-2 bind both the nuclei and cytoplasm of all neurons. ANNA-3 binds the nuclei of glomuerular podocytes in of the renal cortex in 10 of 11 sera. For the same cell type, ANNA-2 binds both the nuclei and cytoplasm in 8 of 32 sera, and ANNA-1 does not bind the podocytes at all. PMID: 11558786 Source: Regenstrief LOINC

Fully-Specified Name

Component
Neuronal nuclear type 3 Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method

Additional Names

Long Common Name
Neuronal nuclear type 3 Ab [Presence] in Serum
Short Name
Hu3 Ab Ser Ql
Display Name
Neuronal nuclear type 3 Ab Ql (S)
Consumer Name Alpha Get Info
Neuronal nuclear type 3 antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.16
Last Updated
Version 2.73 (MIN)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
7583

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Νευρωνικός πυρηνικός τύπος 3 Αντίσωμα:PrThr:Pt:Ορός:Ord:
Synonyms: PrThr Type Νευρωνικό Νευρωνικό πυρηνικό Νευρωνικός πυρηνικός τύπος 3 Πυρηνικό
es-ES Spanish (Spain) Neuronal nuclear tipo 3 Anticuerpos:PrThr:Punto temporal:Suero:Ord:
es-MX Spanish (Mexico) Tipo nuclear neuronal 3 Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:
fr-CA French (Canada) Neuronal nucléaire de type 3, Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:
fr-FR French (France) Hu3 anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:
fr-BE French (Belgium) Type 3 neuronal nucléaire Ac:PrThr:Temps ponctuel:Sérum:Ordinal:
Synonyms: Anticorps
it-IT Italian (Italy) Nucleare neuronale tipo 3 Ab:PrThr:Pt:Siero:Ord:
Synonyms: anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
ko-KR Korean (Korea, Republic Of) 신경 핵 3 형 항체:임의농도:검사시점:혈청:순위척도:
nl-NL Dutch (Netherlands) neuronaal nucleair type 3 As:aanwezigheid:moment:serum:ordinaal:
Synonyms: antistof; antilichaam soort
pl-PL Polish (Poland) Typ 3 neuronalny jądrowy Ab:granica wykrywalności:punkt w czasie:surowica:półilościowy:
Synonyms: Przeciwciała do antygenów jądrowych neuronów typu 3 Przeciwciała onkoneuronalne
pt-BR Portuguese (Brazil) Neuronal nuclear tipo 3 Ac:ACnc:Pt:Soro:Ord:
Synonyms: Nuc; Hu3; ANNA 3; Neuronal nuclear type III; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
ru-RU Russian (Russian Federation) Нейрональный ядерный тип 3 Ат:PrThr:ТчкВрм:Сыв:Пор:
Synonyms: Антинейрональный Антитело Порядковый Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Nöronal nükleer tip 3 Ab:MevcEşik:Zmlı:Ser:Srl:
Synonyms: Çekirdek Mevcut
zh-CN Chinese (China) 神经元细胞核 3 型 抗体:存在情况或阈值:时间点:血清:序数型:
Synonyms: Ⅲ Ab;自身抗体 ANNA 3 Ab ANNA 3 抗体 ANNA 3;ANNA-3;Hu3;神经元核 3 型;神经元细胞核 3 型（Neuronal nuclear type 3，ANNA 3） ANNA-3 Ab ANNA-3 抗体 Hu3 Ab Hu3 抗体 III 三 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 叁 型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 核;胞核 神经元性;神经元的 神经元核 神经元核 3 型 Ab 神经元核 3 型抗体 神经元细胞核 3 型 Ab 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=43102-3