LOINC
Version 2.73

43130-4Bile acid fractions panel [Moles/volume] - Serum or PlasmaActive

Part Description

LP36372-8   Bile acid fractions panel
Bile acids (BAs) play a primary role in digesting dietary fats. Primary BAs are produced in the liver by either the classic or alternative pathway. CYP7A1 controls the production of primary BAs in the liver. The primary BAs (chenodeoxycholic acid and cholic acid) are conjugated to either glycine or taurine to create conjugated primary BAs, which are stored in the gallbladder. Once released into the intestinal circulation, primary BAs are modified by gut bacteria (e.g., deconjugated) to form secondary BAs. Secondary BAs are actively reabsorbed in the terminal ileum, and travel back to the liver through the portal circulation. [PMID:28249284]

Different disorders are associated with various patterns of primary and secondary BA levels. Examples of disorders and their associated BA patterns include:
Disorders of BA synthesis (information from [PMID:18577977]):
1) Inborn errors of bile acid synthesis including cerebrotendinous xanthomatosis, Zellweger syndrome, and a variety of other enzyme deficiencies - low or absent BAs
2) Bile acid conjugation defects - increased levels of unconjugated cholic and deoxycholic acid, lack of chenodeoxycholic acid

Disorders of BA metabolism (information from [PMID:28249284]):
1) Inflammatory bowel disease - reduced deconjugation by gut bacteria, lower levels of secondary BAs
2) Irritable bowel syndrome - reduced deconjugation, increased levels of primary conjugated BAs, lower levels of secondary BAs
3) Short bowel syndrome - reduced levels of secondary and tertiary BAs
4) Obesity - lower levels of both primary BAs Source: Regenstrief LOINC

Panel Hierarchy
Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
43130-4 Bile acid fractions panel [Moles/volume] - Serum or Plasma
Indent14628-2 Bile acid [Moles/volume] in Serum or Plasma R umol/L
Indent38187-1 Bile acid.dihydroxy [Moles/volume] in Serum or Plasma umol/L
Indent38188-9 Bile acid.trihydroxy [Moles/volume] in Serum or Plasma umol/L
Indent30519-3 Chenodeoxycholate [Moles/volume] in Serum or Plasma umol/L
Indent30518-5 Cholate [Moles/volume] in Serum or Plasma umol/L
Indent30520-1 Deoxycholate [Moles/volume] in Serum or Plasma umol/L
Indent53479-2 Dihydroxycholestanoate [Moles/volume] in Serum or Plasma umol/L
Indent93335-8 Glycochenodeoxycholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93334-1 Glycocholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93333-3 Glycodeoxycholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93332-5 Glycohyodeoxycholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93331-7 Glycolithocholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93330-9 Glycoursodeoxycholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93329-1 Hyodeoxycholate [Moles/volume] in Serum or Plasma nmol/mL
Indent74897-0 Lithocholate [Moles/volume] in Serum or Plasma umol/L
Indent93328-3 Taurochenodeoxycholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93327-5 Taurocholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93326-7 Taurodeoxycholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93325-9 Taurohyodeoxycholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93324-2 Taurolithocholate [Moles/volume] in Serum or Plasma nmol/mL
Indent93323-4 Tauroursodeoxycholate [Moles/volume] in Serum or Plasma nmol/mL
Indent55159-8 Ursodeoxycholate [Moles/volume] in Serum or Plasma umol/L
Indent75038-0 Bile acid pattern [Interpretation] in Serum or Plasma Narrative

Fully-Specified Name

Component
Bile acid fractions panel
Property
SCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Bile Acid Fract Pnl SerPl-sCnc
Display Name
Bile acid fractions panel [Moles/Vol]
Consumer Name Alpha
Bile acid fractions panel, Blood

Basic Attributes

Class
PANEL.CHEM
Type
Laboratory
First Released
Version 2.16
Last Updated
Version 2.73
Change Reason
Release 2.67: SYSTEM: Added Plas to be consistent with the terms contained in the panel
Order vs. Observation
Order
Common US Lab Results Rank
7431
Panel Type
Panel

Language Variants Get Info

zh-CNChinese (China)
胆汁酸类成分组套:物质的量浓度:时间点:血清/血浆:定量型:
nl-NLDutch (Netherlands)
galzuren fracties panel:mol/volume:moment:serum of plasma:kwantitatief:
fr-FRFrench (France)
Acides biliaires fractions panel:Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:
it-ITItalian (Italy)
Acido biliare, panel frazionato:SCnc:Pt:Siero/Plasma:Qn:
pt-BRPortuguese (Brazil)
Ácidos biliares fracionados painel:SCnc:Pt:Soro:Qn:
ru-RURussian (Russian Federation)
Желчные кислоты фракционированные панель:МолКонц:ТчкВрм:Сыв/Плаз:Колич:
es-MXSpanish (Mexico)
Panel de fracciones de ácidos biliares:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:
es-ESSpanish (Spain)
Panel ácidos biliares fraccionados:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:
tr-TRTurkish (Turkey)
Safra asidi fraksiyonlamış panel:SubKons:Zmlı:Ser/Plaz:Kant:

LOINC FHIR® API Example - CodeSystem and Questionnaire Requests Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=43130-4 https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/43130-4