43130-4Bile acid fractions panel [Moles/volume] - Serum or PlasmaActive
Part Description
LP36372-8 Bile acid fractions panel
Bile acids (BAs) play a primary role in digesting dietary fats. Primary BAs are produced in the liver by either the classic or alternative pathway. CYP7A1 controls the production of primary BAs in the liver. The primary BAs (chenodeoxycholic acid and cholic acid) are conjugated to either glycine or taurine to create conjugated primary BAs, which are stored in the gallbladder. Once released into the intestinal circulation, primary BAs are modified by gut bacteria (e.g., deconjugated) to form secondary BAs. Secondary BAs are actively reabsorbed in the terminal ileum, and travel back to the liver through the portal circulation. [PMID:28249284]
Different disorders are associated with various patterns of primary and secondary BA levels. Examples of disorders and their associated BA patterns include:
Disorders of BA synthesis (information from [PMID:18577977]):
1) Inborn errors of bile acid synthesis including cerebrotendinous xanthomatosis, Zellweger syndrome, and a variety of other enzyme deficiencies - low or absent BAs
2) Bile acid conjugation defects - increased levels of unconjugated cholic and deoxycholic acid, lack of chenodeoxycholic acid
Disorders of BA metabolism (information from [PMID:28249284]):
1) Inflammatory bowel disease - reduced deconjugation by gut bacteria, lower levels of secondary BAs
2) Irritable bowel syndrome - reduced deconjugation, increased levels of primary conjugated BAs, lower levels of secondary BAs
3) Short bowel syndrome - reduced levels of secondary and tertiary BAs
4) Obesity - lower levels of both primary BAs
Source: Regenstrief LOINC
Panel Hierarchy
Details for each LOINC in Panel
LHC-Forms
| LOINC | Name | R/O/C | Cardinality | Example UCUM Units |
|---|---|---|---|---|
| 43130-4 | Bile acid fractions panel [Moles/volume] - Serum or Plasma | |||
| Indent14628-2 | Bile acid [Moles/volume] in Serum or Plasma | R | umol/L | |
| Indent38187-1 | Bile acid.dihydroxy [Moles/volume] in Serum or Plasma | umol/L | ||
| Indent38188-9 | Bile acid.trihydroxy [Moles/volume] in Serum or Plasma | umol/L | ||
| Indent30519-3 | Chenodeoxycholate [Moles/volume] in Serum or Plasma | umol/L | ||
| Indent30518-5 | Cholate [Moles/volume] in Serum or Plasma | umol/L | ||
| Indent30520-1 | Deoxycholate [Moles/volume] in Serum or Plasma | umol/L | ||
| Indent53479-2 | Dihydroxycholestanoate [Moles/volume] in Serum or Plasma | umol/L | ||
| Indent93335-8 | Glycochenodeoxycholate [Moles/volume] in Serum or Plasma | nmol/mL | ||
| Indent93334-1 | Glycocholate [Moles/volume] in Serum or Plasma | nmol/mL | ||
| Indent93333-3 | Glycodeoxycholate [Moles/volume] in Serum or Plasma | nmol/mL | ||
| Indent93332-5 | Glycohyodeoxycholate [Moles/volume] in Serum or Plasma | nmol/mL | ||
| Indent93331-7 | Glycolithocholate [Moles/volume] in Serum or Plasma | nmol/mL | ||
| Indent93330-9 | Glycoursodeoxycholate [Moles/volume] in Serum or Plasma | nmol/mL | ||
| Indent93329-1 | Hyodeoxycholate [Moles/volume] in Serum or Plasma | nmol/mL | ||
| Indent74897-0 | Lithocholate [Moles/volume] in Serum or Plasma | umol/L | ||
| Indent93328-3 | Taurochenodeoxycholate [Moles/volume] in Serum or Plasma | nmol/mL | ||
| Indent93327-5 | Taurocholate [Moles/volume] in Serum or Plasma | nmol/mL | ||
| Indent93326-7 | Taurodeoxycholate [Moles/volume] in Serum or Plasma | nmol/mL | ||
| Indent93325-9 | Taurohyodeoxycholate [Moles/volume] in Serum or Plasma | nmol/mL | ||
| Indent93324-2 | Taurolithocholate [Moles/volume] in Serum or Plasma | nmol/mL | ||
| Indent93323-4 | Tauroursodeoxycholate [Moles/volume] in Serum or Plasma | nmol/mL | ||
| Indent55159-8 | Ursodeoxycholate [Moles/volume] in Serum or Plasma | umol/L | ||
| Indent75038-0 | Bile acid pattern [Interpretation] in Serum or Plasma Narrative |
Fully-Specified Name
- Component
- Bile acid fractions panel
- Property
- SCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Bile Acid Fract Pnl SerPl-sCnc
- Display Name
- Bile acid fractions panel [Moles/Vol]
- Consumer Name Alpha
- Bile acid fractions panel, Blood
Basic Attributes
- Class
- PANEL.CHEM
- Type
- Laboratory
- First Released
- Version 2.16
- Last Updated
- Version 2.73
- Change Reason
- Release 2.67: SYSTEM: Added Plas to be consistent with the terms contained in the panel
- Order vs. Observation
- Order
- Common US Lab Results Rank
- 7431
- Panel Type
- Panel
Language Variants Get Info
- zh-CNChinese (China)
- 胆汁酸类成分组套:
物质的量浓度: 时间点: 血清/血浆: 定量型: - nl-NLDutch (Netherlands)
- galzuren fracties panel:
mol/volume: moment: serum of plasma: kwantitatief: - fr-FRFrench (France)
- Acides biliaires fractions panel:
Moles/Volume: Ponctuel: Sérum/Plasma: Numérique: - it-ITItalian (Italy)
- Acido biliare, panel frazionato:
SCnc: Pt: Siero/Plasma: Qn: - pt-BRPortuguese (Brazil)
- Ácidos biliares fracionados painel:
SCnc: Pt: Soro: Qn: - ru-RURussian (Russian Federation)
- Желчные кислоты фракционированные панель:
МолКонц: ТчкВрм: Сыв/Плаз: Колич: - es-MXSpanish (Mexico)
- Panel de fracciones de ácidos biliares:
Concentración de sustancias: Punto temporal: Suero o Plasma: Cuantitativo: - es-ESSpanish (Spain)
- Panel ácidos biliares fraccionados:
Concentración de sustancia: Punto temporal: Suero o Plasma: Qn: - tr-TRTurkish (Turkey)
- Safra asidi fraksiyonlamış panel:
SubKons: Zmlı: Ser/Plaz: Kant:
LOINC FHIR® API Example - CodeSystem and Questionnaire Requests Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=43130-4
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/43130-4
LOINC Copyright
Copyright © 2022 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright