LOINC
Version 2.73

43231-0Histone Ab [Units/volume] in Serum by ImmunoassayActive

Part Description

LP16714-5   Histone
Histones are small nuclear proteins that together with dsDNA, represent a nucleosome, the structural unit of chromatin. Anti-histone antibodies are associated with various autoimmune diseases, including systemic lupus erythematosus (SLE), rheumatoid arthritis, Sjogren's syndrome, systemic sclerosis, infectious diseases (including HIV), and some neurological disorders such as Alzheimer's disease and dementia. Nearly all patients with drug-induced SLE have anti-histone antibodies, but they are also present in patients with idiopathic forms of the disease. One study showed a correlation between SLE with positive anti-dsDNA, anti-nucleosome and anti-histone antibodies and renal disease, including proliferative glomerulonephritis. [PMID:24649358] Source: Regenstrief LOINC, PMID: 24649358

Fully-Specified Name

Component
Histone Ab
Property
ACnc
Time
Pt
System
Ser
Scale
Qn
Method
IA

Additional Names

Short Name
Histone Ab Ser IA-aCnc
Display Name
Histone Ab IA Qn (S)
Consumer Name Alpha
Histone antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.17
Last Updated
Version 2.73
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common US Lab Results Rank
3520

Member of these Groups

LG12062-2 Histone Ab|ACnc|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
组蛋白 抗体:任意型浓度:时间点:血清:定量型:免疫测定法
nl-NLDutch (Netherlands)
histon As:eenheid/volume:moment:serum:kwantitatief:immunoassay
et-EEEstonian (Estonia)
Histoon antikehad:Acnc:Pt:S:Qn:IA
fr-BEFrench (Belgium)
Histone Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
fr-CAFrench (Canada)
Histone , Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
fr-FRFrench (France)
Histones anticorps:Arbitraire/Volume:Ponctuel:Sérum:Numérique:Immunoanalyse
de-DEGerman (Germany)
Histon Ak:Arbiträre Konzentration:Zeitpunkt:Serum:Quantitativ:Immunoassay
it-ITItalian (Italy)
Istone Ab:ACnc:Pt:Siero:Qn:IA
pt-BRPortuguese (Brazil)
Histona Ac:ACnc:Pt:Soro:Qn:Imunoensaio
ru-RURussian (Russian Federation)
Гистон Ат:ПроизвКонц:ТчкВрм:Сыв:Колич:IA
es-MXSpanish (Mexico)
Histona Ab:Concentración arbitraria:Punto temporal:Suero:Cuantitativo:Inmunoensayo
es-ESSpanish (Spain)
Histona Anticuerpos:Concentración arbitraria:Punto temporal:Suero:Qn:IA
tr-TRTurkish (Turkey)
Histon Ab:SçKons:Zmlı:Ser:Kant:İA

Example Units

Unit Source
[arb'U]/mL Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=43231-0