43332-6
Equine herpesvirus 1 neutralizing antibody [Titer] in Cerebrospinal Fluid by Neutralization test
Active
Part Descriptions
LP18832-3 Equine herpesvirus 1
Equine herpesvirus 1 (EHV-1) is a virus of the family Herpesviridae that causes abortion in horses. Initial spread of EHV-1 by a newly introduced horse through direct and indirect contact can lead to abortion and perinatal infection in up to 70 percent of a previously unexposed herd. Abortion usually occurs in the last four months of gestation, two to four weeks after infection of the mare. Perinatal (around the time of birth) infection can lead to pneumonia and death. Encephalitis can occur in affected animals, leading to ataxia, paralysis, and death. There is a vaccine available.
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Source: Wikipedia,
Equine herpesvirus 1 (Wikipedia)
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Equine herpesvirus 1 Ab.Neut:
Titr: Pt: CSF: SemiQn: Neut - Long Common Name
- Equine herpesvirus 1 neutralizing antibody [Titer] in Cerebrospinal Fluid by Neutralization test
- Short Name
- EHV1 NAb Titr CSF Nt
- Display Name
- Equine herpesvirus 1 neut ab Neut test (CSF) [Titer]
- Consumer Name Alpha Get Info
- Equine herpesvirus 1 neutralizing antibody, Spinal fluid
Part Model Get Info
- Component
- Equine herpesvirus 1 Ab.Neut
LP430387-3
- Analyte
- Equine herpesvirus 1 Ab.Neut
LP430387-3
- Component Numerator
- Equine herpesvirus 1 Ab.Neut
LP430387-3
- Component Numerator Core
- Equine herpesvirus 1
LP18832-3
- Component Numerator Core Suffix
- Ab.Neut
LP207365-0
- Component Denominator
- NULL
- Component Denominator Core
- NULL
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- Titr
LP6881-9
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- CSF
LP7156-5
- System Core
- CSF
LP7156-5
- Super System
- NULL
- Scale
- SemiQn
LP436123-6
- Method
- Neut
LP6416-4
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.17
- Last Updated
- Version 2.83 (MIN)
- Change Reason
- Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Koňský herpesvirus 1 Ab.neutralizační: |
| el-GR | Greek (Greece) | Ερπητοϊός του ίππου 1 Ab.Neut: Synonyms: Ab.Neut MICRO Pt Titr Αντίσωμα ΕΝΥ Ερπητοϊός του ίππου 1 Ημιποσοτική Ουδετερόφιλα |
| es-ES | Spanish (Spain) | Herpesvirus equino tipo 1 Anticuerpos antineutrófilos: Synonyms: Semicuantitativo |
| es-MX | Spanish (Mexico) | Herpesvirus equino 1 Ab: |
| fr-CA | French (Canada) | Herpèsvirus équin 1 Ac.neut: |
| fr-FR | French (France) | Herpesvirus équin 1 Ac neutralisant: |
| it-IT | Italian (Italy) | Herpesvirus equino 1 Ab.Neut: Synonyms: anticorpo EHV-1 Liquido cerebrospinale Microbiologia Punto nel tempo (episodio) Test di neutralizzazione Titolo |
| nl-NL | Dutch (Netherlands) | equien herpesvirus 1 As.neutraliserend: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Herpeswirus koński 1 Ab.Neutralizujące: Synonyms: Herpeswirus koński Herpeswirus koński typu 1 Przeciwciała do Herpeswirusa końskiego typu 1 Przeciwciała neutralizujące do Herpeswirusa końskiego typu 1 |
| pt-BR | Portuguese (Brazil) | Herpesvírus equino 1 Ac: Synonyms: ; |
| zh-CN | Chinese (China) | 马疱疹病毒 1 型 抗体.中和: Synonyms: Ⅰ Ab; |
Example Units
| Unit | Source |
|---|---|
| {titer} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://