43421-7

Thiopurine methyltransferase [Enzymatic activity/mass] in Red Blood Cells

Active

Part Description

LP19492-5 Thiopurine methyltransferase
Thiopurine methyltransferase (TPMT) is an enzyme that catalyzes the S-methylation of thiopurine drugs including 6-mercatptopurine, thioguanine, and azathioprine (AZA). These drugs are used to treat acute lymphoblastic leukemia, inflammatory bowel disease, rheumatoid arthritis, and organ transplant rejection. Patients with low or absent TPMT activity are at increased risk for toxicity due to increased accumulation of unmetabolised drug. Information from Current Clinical Pharmacology. 2006;1:119-128. Source: Regenstrief Institute

LOINC Names Get Info

Fully-Specified Name: Thiopurine methyltransferase:CCnt:Pt:RBC:Qn:
Long Common Name: Thiopurine methyltransferase [Enzymatic activity/mass] in Red Blood Cells
Short Name: TPMT RBC-cCnt
Display Name: Thiopurine methyltransferase (RBC) [Catalytic activity/Mass]
Consumer Name Alpha Get Info: Thiopurine methyltransferase, Red blood cells

Part Model Get Info

Component
Thiopurine methyltransferase
LP19492-5
- Analyte
  Thiopurine methyltransferase
  LP19492-5
  - Component Numerator
    Thiopurine methyltransferase
    LP19492-5
    - Component Numerator Core
      Thiopurine methyltransferase
      LP19492-5
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
CCnt
LP6790-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
RBC
LP7536-8
- System Core
  RBC
  LP7536-8
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.17
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 12635

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Thiopurinmethyltransferáza:Katalytický obsah:Časový bod:Erytrocyty:Kvantitativní:
el-GR	Greek (Greece)	Μεθυλοτρανσφεράση θειοπουρίνης:CCnt:Pt:Ερυθρά αιμοσφαίρια:Qn: Synonyms: CCnt CHEM Pt Qn Ερυθρά αιμοσφαίρια Μεθυλοτρανσφεράση θειοπουρίνης
es-ES	Spanish (Spain)	Tiopurina metiltransferasa:Contenido catalítico:Punto temporal:Glóbulos rojos:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Tiopurina metiltransferasa:Contenido catalítico:Punto temporal:Eritrocitos:Cuantitativo:
et-EE	Estonian (Estonia)	Tiopuriini metüültransferaas:CCnt:Pt:RBC:Qn: Synonyms: Erütrotsüüdid Juhuslik Kvantitatiivne
fr-CA	French (Canada)	Thiopurine méthyltransférase:Contenu catalytique:Temps ponctuel:GR:Quantitatif:
fr-FR	French (France)	Thiopurine méthyltransférase:Catalytique/Masse:Ponctuel:Érythrocytes:Numérique:
fr-BE	French (Belgium)	Thiopurine méthyltransférase:Contenu catalytique:Temps ponctuel:GR:Quantitatif:
it-IT	Italian (Italy)	Tiopurina metiltransferasi:CCnt:Pt:RBC:Qn: Synonyms: Chimica Contenuto Catalitico Globuli rossi Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	thiopurinemethyltransferase:enzymatische activiteit/massa:moment:erytrocyten:kwantitatief: Synonyms: rode bloedcellen
pt-BR	Portuguese (Brazil)	Tiopurina metiltransferase:CCnt:Pt:Eritroc:Qn: Synonyms: ; TPMT; Catalytic Content; Point in time; Random; Erythrocytes; Red blood corpusles; Red blood cells; Quantitative; QNT; Quant; Quan; Methyl transferase; Chemistry
ru-RU	Russian (Russian Federation)	Тиопурин метилтрансфераза:КаталСод:ТчкВрм:Эритроциты:Колич: Synonyms: Каталитическое содержание Количественный Тиопурин-S-метилтрансфераза Точка во времени;Момент
tr-TR	Turkish (Turkey)	Tiyopürin metiltransferaz:Ktlİçrk:Zmlı:Eritrosit:Kant: Synonyms: RBC
zh-CN	Chinese (China)	硫嘌呤甲基转移酶:催化含量:时间点:红细胞:定量型: Synonyms: RBC;RBCS;红血球;红血细胞;赤血球 TPMT;巯嘌呤甲基转移酶催化含量(单位质量);单位质量的酶单位数化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间转甲基酶

Example Units

Unit	Source
pmol/h/mg{Hb}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.