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Part Description

LP15306-1   5,10-Methylenetetrahydrofolate reductase
In enzymology, a methylenetetrahydrofolate reductase (ferredoxin) (EC 1.5.7.1) is an enzyme that catalyzes the chemical reaction

5-methyltetrahydrofolate + 2 oxidized ferredoxin 5,10-methylenetetrahydrofolate + 2 reduced ferredoxin + 2 H+
Thus, the two substrates of this enzyme are 5-methyltetrahydrofolate and oxidized ferredoxin, whereas its 3 products are 5,10-methylenetetrahydrofolate, reduced ferredoxin, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is 5-methyltetrahydrofolate:ferredoxin oxidoreductase. This enzyme is also called 5,10-methylenetetrahydrofolate reductase. This enzyme participates in one carbon pool by folate. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LOINC Names Get Info

Fully-Specified Name
5,10-Methylenetetrahydrofolate reductase:PrThr:Pt:Ser:Ord:
Long Common Name
5,10-Methylenetetrahydrofolate reductase [Presence] in Serum
Short Name
MTHFR Ser Ql
Display Name
5,10-Methylenetetrahydrofolate reductase Ql (S)
Consumer Name Alpha Get Info
5,10-Methylenetetrahydrofolate reductase, Blood

Part Model Get Info

  • Component
    5,10-Methylenetetrahydrofolate reductase
    LP15306-1
    • Analyte
      5,10-Methylenetetrahydrofolate reductase
      LP15306-1
      • Component Numerator
        5,10-Methylenetetrahydrofolate reductase
        LP15306-1
        • Component Numerator Core
          5,10-Methylenetetrahydrofolate reductase
          LP15306-1
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.17
Last Updated
Version 2.73 (MIN)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
12954

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)5,10-methylentetrahydrofolátreduktáza:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:
el-GRGreek (Greece)Αναγωγάση του 5,10 - µεθυλενοτετραϋδροφυλλικού:PrThr:Pt:Ορός:Ord:
Synonyms: CHEM Ord PrThr Pt Αναγωγάση του 5,10 - µεθυλενοτετραϋδροφυλλικού Ορός
es-ESSpanish (Spain)5,10-Metilenetetrahidrofolato reductasa:PrThr:Punto temporal:Suero:Ord:
es-MXSpanish (Mexico)5,10-metilenotetrahidrofolato reductasa:Presencia o umbral:Punto temporal:Suero:Ordinal:
et-EEEstonian (Estonia)5,10-metüleentetrahüdrofolaadi reduktaas:PrThr:Pt:S:Ord:
Synonyms: Järgarvuline Juhuslik Seerum
fr-CAFrench (Canada)5,10-méthylènetétrahydrofolate réductase:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:
fr-FRFrench (France)5,10-méthylènetétrahydrofolate réductase:Présence/Seuil:Ponctuel:Sérum:Qualitatif:
fr-BEFrench (Belgium)5,10-méthylènetétrahydrofolate réductase:PrThr:Temps ponctuel:Sérum:Ordinal:
Synonyms: MTHFR
it-ITItalian (Italy)5,10-Metilenetetraidrofolato reduttasi:PrThr:Pt:Siero:Ord:
Synonyms: Chimica Presenza o Soglia Punto nel tempo (episodio) Siero
ko-KRKorean (Korea, Republic Of)5,10-메틸렌테트라하이드로폴레이트 환원효소:임의농도:검사시점:혈청:순위척도:
nl-NLDutch (Netherlands)5,10-methyleentetrahydrofolaatreductase:aanwezigheid:moment:serum:ordinaal:
pt-BRPortuguese (Brazil)5,10-Metilenotetrahidrofolato redutase:ACnc:Pt:Soro:Ord:
Synonyms: ; MTHFR; FADH2; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Chemistry
ru-RURussian (Russian Federation)5,10-Метилентетрагидрофолат редуктаза:PrThr:ТчкВрм:Сыв:Пор:
Synonyms: Порядковый Сыворотка Точка во времени;Момент
tr-TRTurkish (Turkey)5,10-Metilentetrahidrofolat reduktaz:MevcEşik:Zmlı:Ser:Srl:
Synonyms: Mevcut
zh-CNChinese (China)5,10-亚甲基四氢叶酸还原酶:存在情况或阈值:时间点:血清:序数型:
Synonyms: FADH2;MTHFR 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=43723-6