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Part Descriptions

LP18167-4   IgA.secretory
Secretory IgA is a dimer with a special secretory component that protects it from proteolytic digestion. IgA protects the GI tract and other endothelial surfaces from infection IgA does not cross the placenta (for practical purposes) Source: Regenstrief Institute

LP18167-4   IgA.secretory
IgA has two subclasses (IgA1 and IgA2) and can exist in a dimeric form called secretory IgA (sIgA). In its secretory form, IgA is the main immunoglobulin found in mucous secretions, including tears, saliva, colostrum and secretions from the genitourinary tract, gastrointestinal tract, prostate and respiratory epithelium. It is also found in small amounts in blood. The secretory component of sIgA protects the immunoglobulin from being degraded by proteolytic enzymes, thus sIgA can survive in the harsh gastrointestinal tract environment and provide protection against microbes that multiply in body secretions.

Decreased or absent IgA, termed selective IgA deficiency, can be a clinically significant immunodeficiency.

Neisseria gonorrhœae (which causes gonorrhea), Streptococcus pneumoniae, and Haemophilus influenzae type B all releases a protease which destroys IgA.

IgA nephropathy is caused by IgA deposits in the kidneys. It is not yet known why IgA deposits occur in this chronic disease. Some theories suggest an abnormality of the immune system results in these deposits.

Celiac disease involves IgA pathology due to the presence of IgA antiendomysial antibodies. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP7565-7   Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
IgA.secretory:PrThr:Pt:Saliva:Ord:
Long Common Name
IgA.secretory [Presence] in Saliva (oral fluid)
Short Name
SIgA Sal Ql
Display Name
IgA.secretory Ql (Sal)
Consumer Name Alpha Get Info
IgA.secretory, Saliva

Part Model Get Info

  • Component
    IgA.secretory
    LP18167-4
    • Analyte
      IgA.secretory
      LP18167-4
      • Component Numerator
        IgA.secretory
        LP18167-4
        • Component Numerator Core
          IgA.secretory
          LP18167-4
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Saliva
    LP7565-7
    • System Core
      Saliva
      LP7565-7
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.17
Last Updated
Version 2.56 (MIN)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)IgA.sekreční:Přítomnost nebo práh:Časový bod:Sliny:Ordinální:
el-GRGreek (Greece)IgA.εκκριτική:PrThr:Pt:Σίελος:Ord:
Synonyms: CHEM IgA.εκκριτική Ord PrThr Pt Ανοσοσφαιρίνη Α Σίελος
es-ESSpanish (Spain)IgA secretora:PrThr:Punto temporal:Saliva:Ord:
es-MXSpanish (Mexico)Secretario de IgA.:Presencia o umbral:Punto temporal:Saliva:Ordinal:
et-EEEstonian (Estonia)IgA.sekretoorne:PrThr:Pt:Sal:Ord:
Synonyms: Immuunglobuliin A Järgarvuline Juhuslik Sülg
fr-CAFrench (Canada)IgA.sécrétoire:Présence-Seuil:Temps ponctuel:Salivaire:Ordinal:
fr-FRFrench (France)Immunoglobuline A secrétoire:Présence/Seuil:Ponctuel:Salive:Qualitatif:
fr-BEFrench (Belgium)IgA.sécrétoire:PrThr:Temps ponctuel:Salivaire:Ordinal:
Synonyms: sIgA
it-ITItalian (Italy)IgA.secretorie:PrThr:Pt:Saliva:Ord:
Synonyms: Chimica Presenza o Soglia Punto nel tempo (episodio)
nl-NLDutch (Netherlands)IgA.secretoir:aanwezigheid:moment:speeksel:ordinaal:
pl-PLPolish (Poland)Ig A.wydzielncza:granica wykrywalności:punkt w czasie:ślina:uporządkowany:
Synonyms: Immunoglobulina A Wydzielnicza immunoglobulina A
pt-BRPortuguese (Brazil)IgA.secretoria:ACnc:Pt:Saliva:Ord:
Synonyms: ; SIgA; Salivary IgA; Immune globulin A; Immunoglobulin A; Arbitrary concentration; Point in time; Random; Sal; Ql; Ordinal; QL; Qualitative; Qual; Screen; Chemistry
ru-RURussian (Russian Federation)IgA.секреторный:PrThr:ТчкВрм:Слюна:Пор:
Synonyms: Порядковый Точка во времени;Момент
tr-TRTurkish (Turkey)IgA.sekretuvar:MevcEşik:Zmlı:Tükürük:Srl:
Synonyms: Mevcut
zh-CNChinese (China)IgA.分泌型:存在情况或阈值:时间点:唾液:序数型:
Synonyms: SIgA;分泌型 IgA;唾液 IgA;唾液型 IgA 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白 A 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 津;津液;涎

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=44590-8