44771-4
Varicella zoster virus Ab [Titer] in Serum by Immunofluorescence
Active
Part Description
LP14853-3 Varicella zoster virus
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.[http://jvi.asm.org/content/88/24/13936.full] In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.[https://grose.lab.uiowa.edu/vzv-genomes-and-evolution] Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Varicella zoster virus Ab
- Property
- Titr
- Time
- Pt
- System
- Ser
- Scale
- SemiQn
- Method
- IF
Additional Names
- Short Name
- VZV Ab Titr Ser IF
- Display Name
- VZV Ab IF (S) [Titer]
- Consumer Name Alpha Get Info
- Varicella zoster virus (VZV; Chickenpox) antibody, Blood
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.17
- Last Updated
- Version 2.75
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 9718
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG32750-8 | Varicella zoster virus |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Varicella-Zoster-Virus Ak: Synonyms: Human alphaherpesvirus 3; |
| es-ES | Spanish (Spain) | Virus Varicella zoster Anticuerpos: Synonyms: Semicuantitativo |
| es-MX | Spanish (Mexico) | Virus de varicela zóster Ab: |
| fr-CA | French (Canada) | Virus varicelle-zona, Ac: |
| fr-FR | French (France) | Varicelle zona virus Ac: |
| it-IT | Italian (Italy) | Varicella zoster, virus Ab: Synonyms: anticorpo Immunofluorescenza (IF) Microbiologia Punto nel tempo (episodio) Siero Titolo Virus della varicella zoster |
| nl-NL | Dutch (Netherlands) | varicella-zostervirus As: Synonyms: antistof; |
| pt-BR | Portuguese (Brazil) | Varicella zoster vírus Ac: Synonyms: ; |
| zh-CN | Chinese (China) | 水痘带状疱疹病毒 抗体: Synonyms: Ab; |
Example Units
| Unit | Source |
|---|---|
| titer | REGENSTRIEF |
| {titer} | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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LOINC Copyright
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