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Part Description

LP16650-1   Histoplasma capsulatum
Histoplasmosis capsulatum is a dimorphic fungal pathogen with filamentous or yeast forms,depending on nutritional factors and temperature.The M antigen is a well-known glycoprotein used as a diagnostic antigen for acute histoplasmosis as it induces the first precipitins during disease. Monoclonal antibodies (mAbs) to the M antigen have been found to modify the pathogenesis of histoplasmosis.Given the shortcomings of current therapies, the administration of mAbs is being investigated. PMID: 22347215 The H band is less commonly seen than the M band and is indicative of chronic or severe acute infections with H capsulatum.

H. capsulatum is found in nature primarily as a saprophytic mold. The mold form is comprised of hyaline septate hyphae, which produce two different asexual reproduction structures, macroconidia and microconidia. The micronidia are believed to be responsible for disease propagation since their 2-6 µm size is well suited for disposition into the distal alveoli. Infection is typically acquired through inhalation of fungal propagules upon disturbances of contaminated soil or excreta. Environmental and genetic factors influence disease manifestations which can range from asymptomatic or mild influenza-like disease to a disseminated sepsis form. Manifestations depend on the magnitude of exposure, the host's immunological status and the virulence of the infective strain. Reactivation of latent infection can result in significant disease, particularly for immunosuppressed individuals. Despite the availability of potent antifungal drugs, nearly one in ten patients hospitalized with histoplasmosis dies. PMID: 17223625 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Histoplasma capsulatum Ab:PrThr:Pt:Ser:Ord:CIE
Long Common Name
Histoplasma capsulatum Ab [Presence] in Serum by Counterimmunoelectrophoresis (CIE)
Short Name
H capsul Ab Ser Ql CIE
Display Name
H. capsulatum Ab CIE Ql (S)
Consumer Name Alpha Get Info
Histoplasma capsulatum antibody, Blood

Part Model Get Info

  • Component
    Histoplasma capsulatum Ab
    LP38405-4
    • Analyte
      Histoplasma capsulatum Ab
      LP38405-4
      • Component Numerator
        Histoplasma capsulatum Ab
        LP38405-4
        • Component Numerator Core
          Histoplasma capsulatum
          LP16650-1
        • Component Numerator Core Suffix
          Ab
          LP20667-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    CIE
    LP6184-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.17
Last Updated
Version 2.56 (MIN)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Histoplasma capsulatum Ab:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:Protisměrná imunoelektroforéza
de-DEGerman (Germany)Histoplasma capsulatum Ak:Nachweis oder Schwellenwert:Zeitpunkt:Serum:Ordinal:Gegenstromimmunelektrophorese (CIE)
el-GRGreek (Greece)Histoplasma capsulatum (Ιστόπλασμα) Αντίσωμα:PrThr:Pt:Ορός:Ord:CIE
Synonyms: CIE Histoplasma capsulatum (Ιστόπλασμα) MICRO Ord PrThr Pt Αντίσωμα Ορός
es-ESSpanish (Spain)Histoplasma capsulatum Anticuerpos:PrThr:Punto temporal:Suero:Ord:Contrainmunoelectroforesis (CIE)
es-MXSpanish (Mexico)Histoplasma capsulatum Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Contrainmunoelectroforesis (CIE)
et-EEEstonian (Estonia)Histoplasma capsulatum antikehad:PrThr:Pt:S:Ord:CIE
Synonyms: Järgarvuline Juhuslik Seerum
fr-CAFrench (Canada)Histoplasma capsulatum, Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Contre-immunoélectrophorèse
fr-FRFrench (France)Histoplasma capsulatum Ac:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Électrosynérèse
fr-BEFrench (Belgium)Histoplasma capsulatum Ac:PrThr:Temps ponctuel:Sérum:Ordinal:Contre-immunoélectrophorèse
Synonyms: Anticorps CIEP
it-ITItalian (Italy)Histoplasma capsulatum Ab:PrThr:Pt:Siero:Ord:CIE
Synonyms: anticorpo Contatoreimmunoelettroforesi (CIE) Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero
nl-NLDutch (Netherlands)Histoplasma capsulatum As:aanwezigheid:moment:serum:ordinaal:counterimmuno-elektroforese
Synonyms: antistof; antilichaam
pt-BRPortuguese (Brazil)Histoplasma capsulatum Ac:ACnc:Pt:Soro:Ord:Contraimunoeletroforese
Synonyms: ; H capsul; H capsulatum; H farciminosum; Histoplasma farciminosum; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Counterimmunoelectrophoresis; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Histo; Histopl; Histoplasmos; Histoplasmosis; Microbiology
tr-TRTurkish (Turkey)Histoplazma Kapsulatum Ab:MevcEşik:Zmlı:Ser:Srl:CIE
Synonyms: Ak Mevcut
zh-CNChinese (China)荚膜组织胞浆菌 抗体:存在情况或阈值:时间点:血清:序数型:反向免疫电泳分析法
Synonyms: Ab;自身抗体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 反向免疫电泳;反向免疫电泳（Counterimmunoelectrophoresis，CIE）;反向免疫电泳法 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 皮疽组织胞浆菌 Ab 皮疽组织胞浆菌;美洲型组织胞浆菌;鼻疽性组织浆菌 皮疽组织胞浆菌抗体 组织胞浆菌属 组织胞浆菌病 美洲型组织胞浆菌 Ab 美洲型组织胞浆菌抗体 荚膜组织胞浆菌 Ab 鼻疽性组织浆菌 Ab 鼻疽性组织浆菌抗体

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=44869-6