45123-7
Cocal virus neutralizing antibody [Titer] in Serum by Neutralization test
Active
Part Descriptions
LP149808-0 Cocal virus
Vesicular stomatitis Indiana virus (VSIV, formerly Indiana 1) and Vesicular stomatitis New Jersey virus (VSNJV) are members of the Vesiculovirus genera of the Rhabdovirus family. They are primarily zoonotic viruses that affect cattle, horses and pigs. Natural VSIV infections encompass two steps, cytolytic infections of mammalian hosts and transmission by insects. The genome is a single molecule of negative-sense RNA that encodes five major proteins: glycoprotein (G), matrix protein (M), nucleoprotein, large protein (L) and phosphoprotein. Half the genome encodes the L protein, which combines with the phosphoprotein to catalyze replication of the mRNA. Other members of the Vesiculovirus genera include Cocal virus (formerly Indiana 2) and Vesicular stomatitis Alagoas virus (formerly Indiana 3).
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia,
Vesicular stomatitis virus Indiana (Wikipedia)
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Cocal virus Ab.Neut:
Titr: Pt: Ser: SemiQn: Neut - Long Common Name
- Cocal virus neutralizing antibody [Titer] in Serum by Neutralization test
- Short Name
- COCV NAb Titr Ser Nt
- Display Name
- Cocal virus neut ab Neut test (S) [Titer]
- Consumer Name Alpha Get Info
- Cocal virus neutralizing antibody, Blood
Part Model Get Info
- Component
- Cocal virus Ab.Neut
LP430341-0
- Analyte
- Cocal virus Ab.Neut
LP430341-0
- Component Numerator
- Cocal virus Ab.Neut
LP430341-0
- Component Numerator Core
- Cocal virus
LP149808-0
- Component Numerator Core Suffix
- Ab.Neut
LP207365-0
- Component Denominator
- NULL
- Component Denominator Core
- NULL
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- Titr
LP6881-9
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- Ser
LP7567-3
- System Core
- Ser
LP7567-3
- Super System
- NULL
- Scale
- SemiQn
LP436123-6
- Method
- Neut
LP6416-4
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.17
- Last Updated
- Version 2.75 (MAJ)
- Change Reason
- Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.; Previous Releases: Indiana serotype 2 is now called Cocal virus [per ICVT]
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Virus Cocal Ab.neutralizační: |
| el-GR | Greek (Greece) | Ιός COCV Ab.Neut: Synonyms: Ab.Neut MICRO Pt Titr Αντίσωμα Ημιποσοτική Ιός Ιός COCV Ορός Ουδετερόφιλα |
| es-ES | Spanish (Spain) | Cocal virus Anticuerpos antineutrófilos: Synonyms: Semicuantitativo |
| es-MX | Spanish (Mexico) | Virus cocal Ab: |
| fr-FR | French (France) | Stomatite vésiculeuse type Indiana 2 virus Ac neutralisant: |
| fr-CA | French (Canada) | Virus Cocal Ac.neut: |
| it-IT | Italian (Italy) | Cocal virus Ab.Neut: Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Siero Test di neutralizzazione Titolo |
| nl-NL | Dutch (Netherlands) | Cocal-virus As.neutraliserend: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Cocal wirus Ab.Neutralizujące: Synonyms: Cocal wirus Przeciwciała do Cocal wirusa Przeciwciała neutralziujące do Cocal wirusa |
| pt-BR | Portuguese (Brazil) | Estomatite vesicular vírus Indiana 2 Ac: Synonyms: ; |
| zh-CN | Chinese (China) | 卡可病毒 抗体.中和: Synonyms: Ab; |
Example Units
| Unit | Source |
|---|---|
| {titer} | Example UCUM Units |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://