45124-5

Vesicular stomatitis Alagoas virus neutralizing antibody [Titer] in Serum by Neutralization test

Active

Part Descriptions

LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP36850-3 Vesicular stomatitis Alagoas virus
Vesicular stomatitis Indiana virus (VSIV, formerly Indiana 1) and Vesicular stomatitis New Jersey virus (VSNJV) are members of the Vesiculovirus genera of the Rhabdovirus family. They are primarily zoonotic viruses that affect cattle, horses and pigs. Natural VSIV infections encompass two steps, cytolytic infections of mammalian hosts and transmission by insects. The genome is a single molecule of negative-sense RNA that encodes five major proteins: glycoprotein (G), matrix protein (M), nucleoprotein, large protein (L) and phosphoprotein. Half the genome encodes the L protein, which combines with the phosphoprotein to catalyze replication of the mRNA. Other members of the Vesiculovirus genera include Cocal virus (formerly Indiana 2) and Vesicular stomatitis Alagoas virus (formerly Indiana 3). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Vesicular stomatitis virus Indiana (Wikipedia)

LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Vesicular stomatitis Alagoas virus Ab.Neut:Titr:Pt:Ser:SemiQn:Neut
Long Common Name: Vesicular stomatitis Alagoas virus neutralizing antibody [Titer] in Serum by Neutralization test
Short Name: VSAV NAb Titr Ser Nt
Display Name: Vesicular stomatitis Alagoas virus neut ab Neut test (S) [Titer]
Consumer Name Alpha Get Info: Vesicular Stomatitis Alagoas virus neutralizing antibody, Blood

Part Model Get Info

Component
Vesicular stomatitis Alagoas virus Ab.Neut
LP430482-2
- Analyte
  Vesicular stomatitis Alagoas virus Ab.Neut
  LP430482-2
  - Component Numerator
    Vesicular stomatitis Alagoas virus Ab.Neut
    LP430482-2
    - Component Numerator Core
      Vesicular stomatitis Alagoas virus
      LP36850-3
    - Component Numerator Core Suffix
      Ab.Neut
      LP207365-0
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Titr
LP6881-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
SemiQn
LP436123-6
Method
Neut
LP6416-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.17
Last Updated: Version 2.75 (MAJ)
Change Reason: Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.; Previous Releases: Vesicular stomatitis virus Indiana 3 is now Vesicular stomatitis Alagoas virus [per ICTV]
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Virus vezikulární stomatitidy Alagoas Ab.neutralizační:Arbitrární koncentrace (titr):Časový bod:Sérum:Semikvantitativní:Neutralizační test
de-DE	German (Germany)	Vesikuläre-Stomatitis-Alagoas-Virus Ak.neutralisierend:Titer:Zeitpunkt:Serum:Semiquantitativ:Neutralisationstest Synonyms: VSAV
el-GR	Greek (Greece)	Ιός φυσαλιδώδους στοματίτιδας ορότυπος Alagoas Ab.Neut:Titr:Pt:Ορός:Ημιποσοτική:Ουδετερόφιλα Synonyms: Ab.Neut MICRO Pt Titr Αντίσωμα Ημιποσοτική Ιός Ιός φυσαλιδώδους στοματίτιδας ορότυπος Alagoas Ορός Ουδετερόφιλα
es-ES	Spanish (Spain)	Virus Indiana 3 de la estomatitis vesicular Anticuerpos antineutrófilos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:Prueba de neutralización Synonyms: Semicuantitativo
es-MX	Spanish (Mexico)	Estomatitis vesicular virus de Alagoas Ab:Título:Punto temporal:Suero:Cuantitativo:Prueba de neutralización
fr-CA	French (Canada)	Virus de la stomatite vésiculaire, type Alagoas Ac.neut:Titre:Temps ponctuel:Sérum:SemiQn:Test de neutralisation
fr-FR	French (France)	Stomatite vésiculeuse type Alagoas virus Ac neutralisant:Titre:Ponctuel:Sérum:Semi-Quantitatif:Neutralisation
it-IT	Italian (Italy)	Stomatite vescicolare, virus dell'Indiana 3 Ab.Neut:Titr:Pt:Siero:SemiQn:Neut Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Siero Test di neutralizzazione Titolo Virus dell''Indiana 3 della stomatite vescicolare
nl-NL	Dutch (Netherlands)	vesiculaire stomatitis Alagoas virus As.neutraliserend:titer:moment:serum:semikwantitatief:neutralisatietest Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Wirus pęcherzykowatego zapalenia jamy ustnej typ Alagoas Ab.Neutralizujące:miano:punkt w czasie:surowica:półilościowy:test neutralizacji Synonyms: Przeciwciała do wirusa pęcherzykowatego zapelnia jamy ustnej typu Alagoas Przeciwciała neutralizujące do wirusa pęcherzykowatego zapelnia jamy ustnej typu Alagoas
pt-BR	Portuguese (Brazil)	Estomatite vesicular vírus Indiana 3 Ac:Título:Pt:Soro:Qn:Teste de neutralização Synonyms: ; VSIV 3; VS; VSV; RhAcdovirus; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Nt; NT; Neutralization test; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; III; Microbiology
zh-CN	Chinese (China)	水泡性口炎病毒 Indiana 型 3 型抗体.中和:滴定度:时间点:血清:半定量型:中和试验 Synonyms: Ab;自身抗体 VSIV 3 Ab VSIV 3 型 Ab VSIV 3 型抗体 VSIV 3 抗体 VSIV 3;VSIV 3 型;水泡性口炎病毒印地安纳型 3 型中和试验;中和抗体;中和传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数时刻;随机;随意;瞬间水泡性口炎病毒 Indiana 型 3 型 Ab 水泡性口炎病毒印地安纳型 3 型 Ab 水泡性口炎病毒印地安纳型 3 型抗体

Example Units

Unit	Source
{titer}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.