46699-5
Fibroblast growth factor 23 [Units/volume] in Plasma
Active
Part Description
LP40488-6 Fibroblast growth factor 23
Fibroblast growth factor 23, or FGF23, is primarily produced in bone and helps regulate phosphate and vitamin D metabolism by binding to receptors on renal tubular cells. It is produced as a 251-amino acid precursor consisting of a signal peptide, N-terminal domain, and C-terminal domain. The bioactive form of FGF23 consists of the N- and C-terminal domains, after the signal peptide is removed, and is also called the "intact" form. Intact FGF23 is cleaved into N-terminal and C-terminal fragments, which are no longer active, though the C-terminal fragment may compete with intact FGF23 for renal tubule receptors and play a role in regulating overall FGF23 activity. The production of FGF23 is regulated by a variety of factors, including calcium and phosphate levels, 1,25 dihydroxyvitamin D, parathyroid hormone, and iron deficiency. Elevated FGF23 levels are associated with chronic kidney disease as well as cardiovascular disease. PMID: 24269946
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Fibroblast growth factor 23
- Property
- ACnc
- Time
- Pt
- System
- Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- FGF-23 Plas-aCnc
- Display Name
- Fibroblast growth factor 23 Qn (P)
- Consumer Name Alpha Get Info
- Fibroblast growth factor 23, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.19
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 7912
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: Fibroblast Growth Factor 23 |
es-ES | Spanish (Spain) | Factor de crecimiento fibroblástico 23: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Factor de crecimiento de fibroblastos 23: |
et-EE | Estonian (Estonia) | Fibroblastide kasvufaktor 23: Synonyms: Juhuslik Kvantitatiivne Plasma |
fr-CA | French (Canada) | Facteur de croissance fibroblaste 23: |
fr-FR | French (France) | FGF-23: |
fr-BE | French (Belgium) | Facteur de croissance fibroblaste 23: |
it-IT | Italian (Italy) | Fibroblasto 23, fattore di crescita: Synonyms: Chimica Concentrazione Arbitraria Fattore di crescita del fibroblasto 23 Plasma Punto nel tempo (episodio) |
nl-NL | Dutch (Netherlands) | fibroblast groeifactor 23: |
pt-BR | Portuguese (Brazil) | Fator 23 de crescimento fibroblástico: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Фибробласт ростовой фактор 23: Synonyms: Количественный Плазма Произвольная концентрация Точка во времени; |
tr-TR | Turkish (Turkey) | Fibroblast büyüme faktörü 23: |
zh-CN | Chinese (China) | 成纤维细胞生长因子 23: Synonyms: FGF 23; |
Example Units
Unit | Source |
---|---|
RU/mL | REGENSTRIEF |
[arb'U];[arb'U]/mL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=46699-5
LOINC Copyright
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