Version 2.77

Part Description

LP40488-6   Fibroblast growth factor 23
Fibroblast growth factor 23, or FGF23, is primarily produced in bone and helps regulate phosphate and vitamin D metabolism by binding to receptors on renal tubular cells. It is produced as a 251-amino acid precursor consisting of a signal peptide, N-terminal domain, and C-terminal domain. The bioactive form of FGF23 consists of the N- and C-terminal domains, after the signal peptide is removed, and is also called the "intact" form. Intact FGF23 is cleaved into N-terminal and C-terminal fragments, which are no longer active, though the C-terminal fragment may compete with intact FGF23 for renal tubule receptors and play a role in regulating overall FGF23 activity. The production of FGF23 is regulated by a variety of factors, including calcium and phosphate levels, 1,25 dihydroxyvitamin D, parathyroid hormone, and iron deficiency. Elevated FGF23 levels are associated with chronic kidney disease as well as cardiovascular disease. PMID: 24269946 Source: Regenstrief LOINC

Fully-Specified Name

Component
Fibroblast growth factor 23
Property
ACnc
Time
Pt
System
Plas
Scale
Qn
Method

Additional Names

Short Name
FGF-23 Plas-aCnc
Display Name
Fibroblast growth factor 23 Qn (P)
Consumer Name Alpha Get Info
Fibroblast growth factor 23, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.19
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
7912

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: FGF23
es-ES Spanish (Spain) Factor de crecimiento fibroblástico 23:Concentración arbitraria:Punto temporal:Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Factor de crecimiento de fibroblastos 23:Concentración arbitraria:Punto temporal:Plasma:Cuantitativo:
et-EE Estonian (Estonia) Fibroblastide kasvufaktor 23:Acnc:Pt:P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma
fr-CA French (Canada) Facteur de croissance fibroblaste 23:Concentration arbitraire:Temps ponctuel:Plasma:Quantitatif:
fr-FR French (France) FGF-23:Arbitraire/Volume:Ponctuel:Plasma:Numérique:
fr-BE French (Belgium) Facteur de croissance fibroblaste 23:Concentration arbitraire:Temps ponctuel:Plasma:Quantitatif:
it-IT Italian (Italy) Fibroblasto 23, fattore di crescita:ACnc:Pt:Plasma:Qn:
Synonyms: Chimica Concentrazione Arbitraria Fattore di crescita del fibroblasto 23 Plasma Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) fibroblast groeifactor 23:eenheid/volume:moment:plasma:kwantitatief:
pt-BR Portuguese (Brazil) Fator 23 de crescimento fibroblástico:ACnc:Pt:Plasma:Qn:
Synonyms: ; FGF-23; FGF23; FGF 23; Autosomal dominant hypophosphatemic rickets; Familial tumoral calcinosis with hyperphosphatemia; Arbitrary concentration; Point in time; Random; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Fac; Fact; Chemistry
ru-RU Russian (Russian Federation) Фибробласт ростовой фактор 23:ПроизвКонц:ТчкВрм:Плаз:Колич:
Synonyms: Количественный Плазма Произвольная концентрация Точка во времени;Момент Фактор роста фибробластов 23
tr-TR Turkish (Turkey) Fibroblast büyüme faktörü 23:SçKons:Zmlı:Plaz:Kant:
zh-CN Chinese (China) 成纤维细胞生长因子 23:任意型浓度:时间点:血浆:定量型:
Synonyms: FGF 23;FGF23;FGF-23;Fibroblast GF 23;伴有高磷血症的家族性肿瘤性普遍性钙质沉着;伴有高磷血症的家族性肿瘤性石未沉着症;伴有高磷血症的家族性肿瘤性钙质沉着;伴有高磷血症的家族性肿瘤性钙质沉着症;伴有高磷酸盐血症的家族性肿瘤性普遍性钙质沉着;伴有高磷酸盐血症的家族性肿瘤性石未沉着症;伴有高磷酸盐血症的家族性肿瘤性钙质沉着;伴有高磷酸盐血症的家族性肿瘤性钙质沉着症;常染色体显性低磷佝偻病;常染色体显性低磷软骨病;常染色体显性低磷酸盐性佝偻症;常染色体显性低磷酸盐性软骨病;纤维 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 因素 时刻;随机;随意;瞬间 系数 纤维原细胞生长因子 纤维母细胞生长因子

Example Units

Unit Source
RU/mL REGENSTRIEF
[arb'U];[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=46699-5