47019-5
CD8 Ag [Presence] in Tissue by Immune stain
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Part Descriptions
LP68355-4 CD8
CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the class I MHC protein. It is predominantly expressed on the surface of cytotoxic T cells, but can also be found on natural killer cells. To function, CD8 forms a dimer, consisting of a pair of CD8 chains. The most common form of CD8 is composed of a CD8-α and CD8-β chain, both members of the immunoglobulin superfamily with an immunoglobulin variable (IgV)-like extracellular domain connected to the membrane by a thin stalk, and an intracellular tail. Less-common homodimers of the CD8-α chain are also expressed on some cells. The extracellular IgV-like domain of CD8-α interacts with to the α3 portion of the Class I MHC molecule.[2] This affinity keeps the T cell receptor of the cytotoxic T cell and the target cell bound closely together during antigen-specific activation. Cytotoxic T cells with CD8 surface protein are called CD8+ T cells.
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Source: Wikipedia,
CD8
LP17729-2 CD8
Found on T-suppressor/cytotoxic cells and some Natural Killer cells; Associated with some mature T-cell neoplasms; Large granular lymphocytosis
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- CD8 Ag:
PrThr: Pt: Tiss: Ord: Immune stain - Long Common Name
- CD8 Ag [Presence] in Tissue by Immune stain
- Short Name
- CD8 Ag Tiss Ql ImStn
- Display Name
- CD8 Ag Immune stain Ql (Tiss)
- Consumer Name Alpha Get Info
- CD8 antigen, Tissue
Part Model Get Info
Basic Attributes
- Class
- CELLMARK
- Type
- Laboratory
- First Released
- Version 2.19
- Last Updated
- Version 2.73 (MIN)
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 15881
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | CD8 Ag: |
| el-GR | Greek (Greece) | CD8 Αντιγόνο: Synonyms: CD8 CELLMARK Ord PrThr Pt Ανοσολογική χρώση Αντιγόνο Ιστός |
| es-ES | Spanish (Spain) | CD8 Antígeno: |
| es-MX | Spanish (Mexico) | CD8 Ag: |
| et-EE | Estonian (Estonia) | CD8 antigeen: Synonyms: Järgarvuline Juhuslik Kude |
| fr-CA | French (Canada) | CD8, Ag: |
| fr-FR | French (France) | CD8 Ag: |
| fr-BE | French (Belgium) | CD8 Ag: Synonyms: Antigène Coloration. Méthode mmunologique |
| it-IT | Italian (Italy) | CD8, Ag: Synonyms: Modelli di superficie cellulare Presenza o Soglia Punto nel tempo (episodio) Tessuto & |
| nl-NL | Dutch (Netherlands) | CD8 Ag: Synonyms: antigeen |
| pl-PL | Polish (Poland) | CD8 Ag: Synonyms: Antygen CD8 CD8 |
| pt-BR | Portuguese (Brazil) | CD8 Ag: Synonyms: Arbitrary concentration; |
| ru-RU | Russian (Russian Federation) | CD8 Аг: Synonyms: Порядковый Ткань и мазки Точка во времени; |
| tr-TR | Turkish (Turkey) | CD8 Ag: Synonyms: Antijen Mevcut |
| zh-CN | Chinese (China) | CD8 抗原: Synonyms: Ag CD8 Ag Leu2 Leu-2 T8 T-8 Tsuppressor 依次型; |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://