Version 2.78

Part Description

LP14400-3   Hepatitis C virus
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

Reference Information

Type Source Reference
Mapping Guidance Regenstrief Help Viral load Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations

Fully-Specified Name

Component
Hepatitis C virus RNA
Property
LnCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method
Probe.amp.tar

Additional Names

Short Name
HCV RNA SerPl NAA+probe-Log#
Display Name
HCV RNA NAA+probe [Log #/Vol]
Consumer Name Alpha Get Info
Hepatitis C virus (HCV), Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.19
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
1503

Member of these Panels

LOINC Long Common Name
75888-8 HCV RNA screening tests - Meaningful Use set
50023-1 Hepatitis C virus RNA panel (viral load) in Serum or Plasma by NAA with probe detection

Member of these Groups Get Info

LOINC Group Group Name
LG32754-0 Hepatitis C virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Hepatitis-C-Virus RNA:Logarithmische Anzahl pro Volumen:Zeitpunkt:Serum oder Plasma:Quantitativ:Zielfragmentamplifikation mit Sondendetektion
Synonyms: Hepacivirus C; HCV
es-ES Spanish (Spain) Virus Hepatitis C RNA:Logaritmo de concentración:Punto temporal:Suero o Plasma:Qn:Sonda con amplificación dirigida
Synonyms: Cuantitativo
es-MX Spanish (Mexico) ARN del virus de la hepatitis C:Concentración del número de registro:Punto temporal:Suero o Plasma:Cuantitativo:Amplificación de ácidos nucleicos con detección de sonda
fr-CA French (Canada) Virus de l'hépatite C ARN:Concentration logarithmique:Temps ponctuel:Sérum/Plasma:Quantitatif:Sonde avec amplification de la cible
fr-FR French (France) Hépatite C virus ARN:Log Nombre/Volume:Ponctuel:Sérum/Plasma:Numérique:PCR amplification de cible
fr-BE French (Belgium) Virus de l'hépatite C ARN:Concentration logarithmique:Temps ponctuel:Sérum/Plasma:Quantitatif:Sonde avec amplification de la cible
Synonyms: HCV
it-IT Italian (Italy) Epatite C, virus RNA:LnCnc:Pt:Siero/Plasma:Qn:Sonda.amp.tar
Synonyms: Concentrazione logaritmica Microbiologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''epatite C
nl-NL Dutch (Netherlands) Hepatitis C-virus RNA:logaritmisch aantal/volume:moment:serum of plasma:kwantitatief:probe-detectie
Synonyms: probe.amp.tar
pt-BR Portuguese (Brazil) Hepatite C vírus RNA:LnCnc:Pt:Sor/Plas:Qn:Sonda com limite de detecção da amplificação de alvo
Synonyms: Ribonucleic acid; HCV; Hep C; Log#; Log NCNC; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; PCR; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Amplified; Hepatit; Hepatis; Microbiology; Viral load
ru-RU Russian (Russian Federation) Гепатита С вирус РНК:ЛогЧислКонц:ТчкВрм:Сыв/Плаз:Колич:Проба.усил.миш
Synonyms: ДНК проба;ДНК зонд Количественный Логарифм числ концентрация Плазма Проба с мишени усилением Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Hepatit C virüsü RNA:LnKons:Zmlı:Ser/Plaz:Kant:Prob.amf.hdf
uk-UA Ukrainian (Ukraine) Вірусу Гепатиту С РНК:Log Чисельна Концентрація:МоментЧасу:Сироватка/Плазма:Кількісно:Зонд-детекція. цільова аміпліфікація НК
Synonyms: 3 Self-Sustaining Sequence Replication; 3SR SR; Amplif; Amplification; Amplified; DNA NUCLEIC ACID PROBE; DNA probe; HCV; Hep; Hep C; Hepatis; Hepatit; Hepatology; ID; Infectious Disease; InfectiousDisease; LAT; LCR; Ligase chain reaction; Ligation-activated transcription; Liver; Log NCNC; Log#; Microbiology; NAA+probe; NAAT; NASBA; Nucleic acid sequence based analysis; PCR; Pl; Plasma; Plsm; Point in time; Polymerase chain reaction; Probe amp; Probe with ampification; Probe with target amplification; QBR; QNT; Quan; Quant; Quantitative; Random; Ribonucleic acid; SDA; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR; Strand Displacement Amplification; TMA; Transcription mediated amplification; UniversalLabOrders; Viral load
zh-CN Chinese (China) 丙型肝炎病毒 RNA:对数型数量或计数浓度:时间点:血清/血浆:定量型:探针法.基因扩增.靶向
Synonyms: C 型;丙;丙型 HCV RNA HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 Hep C RNA 丙肝病毒 RNA 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 对数型数量或计数浓度 探针法.扩增.靶向 对数型数量浓度 探针法.基因扩增.靶向 对数型数量浓度 探针法.扩增.靶向 对数型数量浓度;对数型计数浓度;数量或计数型浓度之对数 对数型计数浓度 探针法.基因扩增.靶向 对数型计数浓度 探针法.扩增.靶向 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 核糖核酸;Ribonucleic acid 病毒负荷 病毒负荷量 病毒负载 病毒载量 病毒载量（Viral load） 经过扩增的 肝 肝炎病毒 C 型 RNA 脱氧核糖核酸探针 血清或血浆

Example Units

Unit Source
log copies/mL REGENSTRIEF
{log_copies}/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=47252-2