47255-5

Procollagen type I.N-terminal propeptide [Mass/volume] in Serum or Plasma

Active

Part Descriptions

LP57671-7 Procollagen type I.N-terminal propeptide
Procollagen type I N-terminal propeptide is considered a sensitive marker of bone formation and it is particularly useful for monitoring treatment for osteoporosis in postmenopausal women, and Paget's disease of the bone. Type I collagen constitutes 90% of bone proteins and is synthesized as type I procollagen. During the extracellular processing of type I procollagen, the amino terminal [N-terminal propeptide of type I collagen] and carboxy terminal propeptide are separated. These propeptides circulate in the bloodstream, where they are markers of bone formation. Procollagen type I N-terminal propeptide circulates as different forms, including the intact authentic trimeric procollagen type I N-terminal propeptide, a monomer, and several fragments. PMID: 17998267 Source: Regenstrief LOINC, PMID: 17998267

LP57671-7 Procollagen type I.N-terminal propeptide
A procollagen peptide contains an additional peptide sequence, termed the propeptide, at its amino and carboxy terminal ends. Collagen types I, II, III, IV and V are synthesized as precursor molecules called procollagens. Propeptides facilitate the winding of procollagen molecules into a triple-helix conformation within the endoplasmic reticulum. These propeptides are then cleaved from the collagen triple helix molecule during its secretion, after which the collagens polymerize into extracellular collagen fibrils. Thus, the amount of free propeptides directly correlates with collagen molecule synthesis. Procollagen Type I C-peptide (PIP) has also been extensively referenced in correlation studies between collagen levels and certain health disorders such as bone disease, alcoholic liver disease, liver cirrhosis and cirrhosis (Borrmann type IV) adenocarcinoma of the stomach. Source: Regenstrief Help

LOINC Names Get Info

Fully-Specified Name: Procollagen type I.N-terminal propeptide:MCnc:Pt:Ser/Plas:Qn:
Long Common Name: Procollagen type I.N-terminal propeptide [Mass/volume] in Serum or Plasma
Short Name: PINP SerPl-mCnc
Display Name: Procollagen type I.N-terminal propeptide [Mass/Vol]
Consumer Name Alpha Get Info: Procollagen Type I.N-terminal Propeptide, Blood

Part Model Get Info

Component
Procollagen type I.N-terminal propeptide
LP57671-7
- Analyte
  Procollagen type I.N-terminal propeptide
  LP57671-7
  - Component Numerator
    Procollagen type I.N-terminal propeptide
    LP57671-7
    - Component Numerator Core
      Procollagen type I.N-terminal propeptide
      LP57671-7
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.19
Last Updated: Version 2.82 (MAJ)
Order vs. Observation: Both
Common Test Rank Get Info: 4299

Member of these Groups Get Info

LOINC Group	Group Name
LG18642-5	Procollagen type I.N-terminal propeptide\|MCnc\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
ar-JO	Arabic (Jordan)	البروكولاجين من النوع الأول ، الببتيد الأميني الطرفي في المصل ( بتقنية الكتلة / الحجم )
cs-CZ	Czech (Czechia)	Prokolagen typu I.N-terminální propeptid:Hmotnostní koncentrace:Časový bod:Sérum:Kvantitativní:
de-AT	German (Austria)	Synonyms: Prokollagen Typ 1 NP
de-DE	German (Germany)	Prokollagenpeptid Typ 1.Propeptid N-Terminal:Massenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:
el-GR	Greek (Greece)	Προκολλαγόνο τύπου I.N-τερματικό προπεπτίδιο:MCnc:Pt:Ορός/Πλάσμα:Qn: Synonyms: CHEM I MCnc N Pt Qn Type Ορός Ορός/Πλάσμα Πλάσμα Προκολλαγόνο τύπου I Προκολλαγόνο τύπου I.N-τερματικό προπεπτίδιο
es-ES	Spanish (Spain)	Péptido N-terminal del procolágeno tipo I:Concentración de masa:Punto temporal:Suero o Plasma:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Propéptido N-terminal de procolágeno tipo I.:Concentración de masa:Punto temporal:Suero:Cuantitativo:
et-EE	Estonian (Estonia)	I tüüpi prokollageeni N-fragment:MCnc:Pt:S/P:Qn: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA	French (Canada)	Procollagène type I.N-terminal propeptide:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR	French (France)	Procollagène type 1 propeptide N terminal:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE	French (Belgium)	Peptide du procollagène.type 1 N-terminal:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif: Synonyms: PNPP-1
it-IT	Italian (Italy)	Procollagene, peptide.tipo 1 N-Terminale:MCnc:Pt:Siero/Plasma:Qn: Synonyms: Chimica Concentrazione di Massa Peptide del procollagene di tipo 1 Peptide del procollagene di tipo 1 N-Terminale Plasma Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL	Dutch (Netherlands)	procollageenpeptide.type 1 N-terminaal:massa/volume:moment:serum of plasma:kwantitatief: Synonyms: soort
pl-PL	Polish (Poland)	Prokolagen typu I.N-końcowy propeptyd:stężenie masowe:punkt w czasie:surowica lub osocze:ilościowy: Synonyms: N-końcowy propeptyd prokolagenu typu I;PINP
pt-BR	Portuguese (Brazil)	Peptídeo procolágeno.Tipo 1 N-Terminal:MCnc:Pt:Soro:Qn: Synonyms: ; Procollagen Peptide.1 N-term; PINP; P1NP; Procollagen Peptide1; Mass concentration; Level; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Pept; I; Chemistry
ru-RU	Russian (Russian Federation)	Проколлаген пептид.тип 1 N-Терминаль:МассКонц:ТчкВрм:Сыв/Плаз:Колич: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Prokollajen peptid.tip 1 N-Terminal:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN	Chinese (China)	前胶原肽.I 型 N-末端:质量浓度:时间点:血清/血浆:定量型: Synonyms: 1 型前胶原肽 N-末端;1 型前胶原肽氨基末端;I 型前胶原肽 N-末端;I 型前胶原肽氨基末端;P1NP;PINP;前胶原肽.1 型氨基末端;前胶原肽.1 型 N-末端;前胶原肽.I 型氨基末端 I 型 N 型前胶原.I 型;前胶原肽.1 型;1 型前胶原肽;1 型原骨胶原肽;1 型溶胶原肽;1 型酸溶原胶原蛋白肽;1 型酸溶胶原蛋白肽;I 型前胶原肽;I 型原骨胶原肽;I 型溶胶原肽;I 型酸溶原胶原蛋白肽;I 型酸溶胶原蛋白肽;前胶原肽.I 型;原骨胶原肽.1 型;原骨胶原肽.I 型;溶胶原肽.1 型;溶胶原肽.I 型;酸溶原胶原蛋白肽.1 型;酸溶原胶原蛋白肽.I 型;酸溶胶原蛋白肽.1 型;酸溶胶原蛋白肽.I 型化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺型时刻;随机;随意;瞬间水平;浓度;质量浓度(单位体积) 血清或血浆

Example Units

Unit	Source
ug/L	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.