Version 2.78

Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Fully-Specified Name

Component
Cytomegalovirus Ab
Property
PrThr
Time
Pt
System
Ser/Plas^Donor
Scale
Ord
Method

Additional Names

Short Name
CMV Ab SerPl Donr Ql
Display Name
CMV Ab Ql (S/P donor)
Consumer Name Alpha Get Info
Cytomegalovirus (CMV) antibody, Donor Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.19
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Updated System from Ser to Ser/Plas since this test can also be done on plasma.
Order vs. Observation
Both
Common Test Rank Get Info
8326

Member of these Panels

LOINC Long Common Name Answer List Answer List Type Answers
54037-7 HEDIS 2009 panel
57820-3 HEDIS 2010 panel
60442-1 HEDIS 2011 panel
67767-4 HEDIS 2012 panel
72199-3 HEDIS 2013 panel
74234-6 HEDIS 2014 Value Sets
75868-0 HEDIS 2015 Value Sets
79544-3 HEDIS 2016 Value Sets
82955-6 HEDIS 2017 Value Sets
87625-0 HEDIS 2018 Value Sets
95356-2 Revised Pretransplant Assessment of Mortality (PAM) Score panel LL360-9 Normative 2

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Cytomegalie-Virus Ak:Nachweis oder Schwellenwert:Zeitpunkt:Serum oder Plasma^Donor:Ordinal:
Synonyms: CMV
es-ES Spanish (Spain) Citomegalovirus Anticuerpos:PrThr:Punto temporal:Suero o Plasma^donante:Ord:
es-MX Spanish (Mexico) Citomegalovirus Ab:Presencia o umbral:Punto temporal:Suero o plasma ^ Donante:Ordinal:
et-EE Estonian (Estonia) Tsütomegaloviirus antikehad:PrThr:Pt:S/P^doonor:Ord:
Synonyms: Järgarvuline Juhuslik Plasma Seerum Seerum või plasma
fr-CA French (Canada) Cytomégalovirus, Ac:Présence-Seuil:Temps ponctuel:Sérum/Plasma^Donneur:Ordinal:
fr-FR French (France) Cytomégalovirus Ac:Présence/Seuil:Ponctuel:Sérum/Plasma du donneur:Qualitatif:
fr-BE French (Belgium) Cytomégalovirus Ac:PrThr:Temps ponctuel:Sérum/Plasma^Donneur:Ordinal:
Synonyms: Anticorps CMV
it-IT Italian (Italy) Citomegalovirus Ab:PrThr:Pt:Siero/Plasma^donatore:Ord:
Synonyms: anticorpo Microbiologia Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL Dutch (Netherlands) Cytomegalovirus As:aanwezigheid:moment:serum of plasma^donor:ordinaal:
Synonyms: antistof; antilichaam
pl-PL Polish (Poland) Wirus cytomegalii Ab:granica wykrywalności:punkt w czasie:surowica lub osocze^dawca:półilościowy:
Synonyms: Cytomegalowirus Przecwciała do cytomegalowirusa
pt-BR Portuguese (Brazil) Citomegalovírus Ac:ACnc:Pt:Soro^doador:Ord:
Synonyms: ; CMV; Cytomgal; Cytomegalo virus; Arbitrary concentration; Point in time; Random; Serum; SR; Donr; Ql; Ordinal; QL; Qualitative; Qual; Screen; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
ru-RU Russian (Russian Federation) Цитомегаловирус Ат:PrThr:ТчкВрм:Сыв/Плаз^донор:Пор:
Synonyms: Антитело Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Cytomegalovirus Ab:MevcEşik:Zmlı:Ser/Plaz^verici:Srl:
Synonyms: Ak Mevcut
zh-CN Chinese (China) 巨细胞病毒 抗体:存在情况或阈值:时间点:血清/血浆^供体:序数型:
Synonyms: Ab;自身抗体 CMV Ab CMV 抗体 CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒 供血者;捐献者;捐赠者;给予体;给体;超系统 - 供体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 巨细胞病毒 Ab 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 血清/血浆^捐赠者 血清或血浆

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=47430-4