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Part Description

LP61819-6   Fibroblast growth factor 23.C-terminal
Fibroblast growth factor 23, or FGF23, is primarily produced in bone and helps regulate phosphate and vitamin D metabolism by binding to receptors on renal tubular cells. It is produced as a 251-amino acid precursor consisting of a signal peptide, N-terminal domain, and C-terminal domain. The bioactive form of FGF23 consists of the N- and C-terminal domains after the signal peptide is removed, and is also called the "intact" form. Serine endopeptidase pro-protein convertases cleave the intact form into inactive N-terminal and C-terminal fragments, though the C-terminal fragment may compete with intact FGF23 by binding to renal tubule receptors and thus play a role in regulating overall FGF23 activity. The production of FGF23 is regulated by a variety of factors, including calcium and phosphate levels, 1,25 dihydroxyvitamin D, parathyroid hormone, and iron deficiency. Elevated FGF23 levels are associated with chronic kidney disease as well as cardiovascular disease. PMID: 24269946 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Fibroblast growth factor 23.C-terminal:ACnc:Pt:Plas:Qn:
Long Common Name
Fibroblast growth factor 23.C-terminal [Units/volume] in Plasma
Short Name
FGF-23 c-term Plas-aCnc
Display Name
Fibroblast growth factor 23.C-terminal Qn (P)
Consumer Name Alpha Get Info
Fibroblast Growth Factor 23.C-terminal, Blood

Part Model Get Info

  • Component
    Fibroblast growth factor 23.C-terminal
    LP61819-6
    • Analyte
      Fibroblast growth factor 23.C-terminal
      LP61819-6
      • Component Numerator
        Fibroblast growth factor 23.C-terminal
        LP61819-6
        • Component Numerator Core
          Fibroblast growth factor 23.C-terminal
          LP61819-6
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    ACnc
    LP6773-8
  • Time
    Pt
    LP6960-1
  • System
    Plas
    LP7479-1
    • System Core
      Plas
      LP7479-1
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.21
Last Updated
Version 2.70 (MIN)
Change Reason
Added "23" to the Component to clarify that this term represents the C-terminus of fibroblast growth factor 23 and not 21. The short name and related names have always included the 23.
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
ar-JOArabic (Jordan)الطرف الكربوكسيلي لعامل نمو الخلايا الليفية 23 في البلازما ( بتقنية الوحدات / الحجم )
cs-CZCzech (Czechia)Fibroblastový růstový faktor 23.C-terminální:Arbitrární koncentrace:Časový bod:Plazma:Kvantitativní:
el-GRGreek (Greece)Αυξητικός παράγοντας ινοβλαστών 23.C-τερματικό:ACnc:Pt:Πλάσμα:Qn:
Synonyms: ACnc C CHEM Pt Qn Αυξητικός παράγοντας ινοβλαστών 23 Αυξητικός παράγοντας ινοβλαστών 23.C-τερματικό Πλάσμα
es-ESSpanish (Spain)Factor de crecimiento fibroblástico 23 (FGF-23) C-terminal:Concentración arbitraria:Punto temporal:Plasma:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Factor de crecimiento de fibroblastos 23.C-terminal:Concentración arbitraria:Punto temporal:Plasma:Cuantitativo:
et-EEEstonian (Estonia)Fibroblastide kasvufaktor.C-terminaalne:Acnc:Pt:P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma
fr-CAFrench (Canada)Facteur de croissance fibroblaste 23.C-terminal:Concentration arbitraire:Temps ponctuel:Plasma:Quantitatif:
fr-FRFrench (France)FGF-23 extrémité C terminale:Arbitraire/Volume:Ponctuel:Plasma:Numérique:
fr-BEFrench (Belgium)Facteur de croissance fibroblaste.C-terminal:Concentration arbitraire:Temps ponctuel:Plasma:Quantitatif:
it-ITItalian (Italy)Fibroblasto, fattore di crescita 23.C-terminale:ACnc:Pt:Plasma:Qn:
Synonyms: Chimica Concentrazione Arbitraria Fattore di crescita del fibroblasto 23 Fattore di crescita del fibroblasto 23.C-terminale Plasma Punto nel tempo (episodio)
nl-NLDutch (Netherlands)fibroblast groeifactor.C-terminaal:eenheid/volume:moment:plasma:kwantitatief:
pl-PLPolish (Poland)Czynnik wzrostu fibroblastów 23.C-końcowy:stężenie w jednostkach umownych:punkt w czasie:osocze:ilościowy:
Synonyms: C-końcowy fragment FGF23 FGF-23
pt-BRPortuguese (Brazil)Fator de crescimento fibroblástico.C-terminal:ACnc:Pt:Plasma:Qn:
Synonyms: ; FGF-23 c-term; Arbitrary concentration; Point in time; Random; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Fac; Fact; Chemistry
ru-RURussian (Russian Federation)Фибробласт ростовой фактор.C-терминаль:ПроизвКонц:ТчкВрм:Плаз:Колич:
Synonyms: Количественный Плазма Произвольная концентрация Точка во времени;Момент Фактор роста фибробластов 23 Фактор роста фибробластов.C-терминаль
tr-TRTurkish (Turkey)Fibroblast büyüme faktörü.C-terminal:SçKons:Zmlı:Plaz:Kant:
zh-CNChinese (China)成纤维细胞生长因子.C-末端:任意型浓度:时间点:血浆:定量型:
Synonyms: C 型;丙;丙型 FGF 23;FGF23;FGF-23;Fibroblast GF 23;伴有高磷血症的家族性肿瘤性普遍性钙质沉着;伴有高磷血症的家族性肿瘤性石未沉着症;伴有高磷血症的家族性肿瘤性钙质沉着;伴有高磷血症的家族性肿瘤性钙质沉着症;伴有高磷酸盐血症的家族性肿瘤性普遍性钙质沉着;伴有高磷酸盐血症的家族性肿瘤性石未沉着症;伴有高磷酸盐血症的家族性肿瘤性钙质沉着;伴有高磷酸盐血症的家族性肿瘤性钙质沉着症;常染色体显性低磷佝偻病;常染色体显性低磷软骨病;常染色体显性低磷酸盐性佝偻症;常染色体显性低磷酸盐性软骨病;纤维 FGF-23.C-末端;FGF-23.C-端;FGF-23.羧基末端;FGF-23.羧基端;成纤维细胞 GF.C-末端;成纤维细胞 GF.C-端;成纤维细胞 GF.羧基末端;成纤维细胞 GF.羧基端;成纤维细胞生长因子.C-端;成纤维细胞生长因子.羧基末端;成纤维细胞生长因子.羧基端;纤维母细胞 GF.C-末端;纤维母细胞 GF.C-端;纤维母细胞 GF.羧基末端;纤维母细胞 GF.羧基端;纤维母细胞生长因子.C-末端;纤维母细胞生长因子.C-端;纤维母细胞生长因子.羧基末端;纤维母细胞生长因子.羧基端 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 因素 时刻;随机;随意;瞬间 系数 纤维原细胞生长因子 纤维母细胞生长因子

Example Units

UnitSource
[arb'U]/mLExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=47855-2