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Part Description

LP15821-9   Propionyl CO-A carboxylase
Propionyl-CoA carboxylase catalyses the carboxylation reaction of propionyl CoA. The product of the reaction is (S)-methylmalonyl CoA. Propionyl CoA is the end product of metabolism of odd-chain fatty acids, and is also a metabolite of most methyl-branched fatty acids. It is also the main metabolite of valine, and together with acetyl-CoA, is a metabolite of isoleucine, as well as a methionine metabolite. Propionyl-CoA is thus of great importance as a glucose precursor. (S)-Methylmalonyl-CoA is not directly utilizable by animals; it is acted on by a racemase to give (R)-methylmalonyl-CoA. The latter is converted by methylmalonyl-CoA mutase (one of a very few Vitamin B12 dependent enzymes) to give succinyl-CoA. The latter is converted to oxaloacetate and then malate in the Krebs cycle. Export of malate into the cytosol leads to formation of oxaloacetate, phosphoenol pyruvate, and other gluconeogenic intermediates.

A deficiency is associated with propionic acidemia. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LOINC Names Get Info

Fully-Specified Name
Propionyl CO-A carboxylase:CCnt:Pt:Fibroblasts:Qn:
Long Common Name
Propionyl CoA Carboxylase [Enzymatic activity/mass] in Fibroblast
Short Name
PCCA Fib-cCnt
Display Name
Propionyl CoA Carboxylase (Fibroblast) [Catalytic activity/Mass]
Consumer Name Alpha Get Info
Propionyl coA carboxylase, Fibroblast

Part Model Get Info

  • Component
    Propionyl CO-A carboxylase
    LP15821-9
    • Analyte
      Propionyl CO-A carboxylase
      LP15821-9
      • Component Numerator
        Propionyl CO-A carboxylase
        LP15821-9
        • Component Numerator Core
          Propionyl CO-A carboxylase
          LP15821-9
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    CCnt
    LP6790-2
  • Time
    Pt
    LP6960-1
  • System
    Fibroblasts
    LP7234-0
    • System Core
      Fibroblasts
      LP7234-0
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.21
Last Updated
Version 2.70 (MIN)
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Propionyl-CoA-karboxyláza:Katalytický obsah:Časový bod:Fibroblast:Kvantitativní:
el-GRGreek (Greece)Καρβοξυλάση προπιονυλοσυνένζυμου Α:CCnt:Pt:Ινοβλάστες:Qn:
Synonyms: A CCnt CHEM Pt Qn Ινοβλάστες Καρβοξυλάση προπιονυλοσυνένζυμου Α
es-ESSpanish (Spain)Propionil CoA carboxilasa:Contenido catalítico:Punto temporal:Fibroblastos:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Propionil CO-A carboxilasa:Contenido catalítico:Punto temporal:Fibroblasto:Cuantitativo:
fr-CAFrench (Canada)Propionyl-CoA carboxylase:Contenu catalytique:Temps ponctuel:Fibroblastes:Quantitatif:
fr-FRFrench (France)Propionyl CoA carboxylase:Catalytique/Masse:Ponctuel:Fibroblastes:Numérique:
fr-BEFrench (Belgium)Propionyl-CoA carboxylase:Contenu catalytique:Temps ponctuel:Fibroblastes:Quantitatif:
it-ITItalian (Italy)Propionil CO-A carbossilasi:CCnt:Pt:Fibroblasti:Qn:
Synonyms: Chimica Contenuto Catalitico Fibroblasto Propionil CoA Carbossilasi Punto nel tempo (episodio)
nl-NLDutch (Netherlands)propionyl CO-A carboxylase:enzymatische activiteit/massa:moment:fibroblast:kwantitatief:
pt-BRPortuguese (Brazil)Propionil CO-A carboxilase:CCnt:Pt:Fibroblastos:Qn:
Synonyms: ; PCC; Catalytic Content; Point in time; Random; Fib; Fibr; Quantitative; QNT; Quant; Quan; Chemistry
ru-RURussian (Russian Federation)Пропионил CoA карбоксилаза:КаталСод:ТчкВрм:Фибробласты:Колич:
Synonyms: Каталитическое содержание Количественный Пропионил КоА карбоксилаза Точка во времени;Момент
tr-TRTurkish (Turkey)Propiyonil KoA karboksilaz:Ktlİçrk:Zmlı:Fibroblastlar:Kant:
zh-CNChinese (China)丙酰 CoA 羧化酶:催化含量:时间点:成纤维细胞:定量型:
Synonyms: A 型 PCC;丙酰辅酶 A 羧化酶 催化含量(单位质量);单位质量的酶单位数 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 纤维原细胞;纤维母细胞

Example Units

UnitSource
nmol/min/mg{protein}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=47874-3