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Part Description

LP16650-1   Histoplasma capsulatum
Histoplasmosis capsulatum is a dimorphic fungal pathogen with filamentous or yeast forms,depending on nutritional factors and temperature.The M antigen is a well-known glycoprotein used as a diagnostic antigen for acute histoplasmosis as it induces the first precipitins during disease. Monoclonal antibodies (mAbs) to the M antigen have been found to modify the pathogenesis of histoplasmosis.Given the shortcomings of current therapies, the administration of mAbs is being investigated. PMID: 22347215 The H band is less commonly seen than the M band and is indicative of chronic or severe acute infections with H capsulatum.

H. capsulatum is found in nature primarily as a saprophytic mold. The mold form is comprised of hyaline septate hyphae, which produce two different asexual reproduction structures, macroconidia and microconidia. The micronidia are believed to be responsible for disease propagation since their 2-6 µm size is well suited for disposition into the distal alveoli. Infection is typically acquired through inhalation of fungal propagules upon disturbances of contaminated soil or excreta. Environmental and genetic factors influence disease manifestations which can range from asymptomatic or mild influenza-like disease to a disseminated sepsis form. Manifestations depend on the magnitude of exposure, the host's immunological status and the virulence of the infective strain. Reactivation of latent infection can result in significant disease, particularly for immunosuppressed individuals. Despite the availability of potent antifungal drugs, nearly one in ten patients hospitalized with histoplasmosis dies. PMID: 17223625 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Histoplasma capsulatum Ag:PrThr:Pt:Tiss:Ord:Immune stain
Long Common Name
Histoplasma capsulatum Ag [Presence] in Tissue by Immune stain
Short Name
H capsul Ag Tiss Ql ImStn
Display Name
H. capsulatum Ag Immune stain Ql (Tiss)
Consumer Name Alpha Get Info
Histoplasma capsulatum antigen, Tissue

Part Model Get Info

  • Component
    Histoplasma capsulatum Ag
    LP38409-6
    • Analyte
      Histoplasma capsulatum Ag
      LP38409-6
      • Component Numerator
        Histoplasma capsulatum Ag
        LP38409-6
        • Component Numerator Core
          Histoplasma capsulatum
          LP16650-1
        • Component Numerator Core Suffix
          Ag
          LP20666-1
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Tiss
    LP7641-6
    • System Core
      Tiss
      LP7641-6
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Immune stain
    LP6333-1

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.21
Last Updated
Version 2.56 (MIN)
Change Reason
There is only one species in the genus Histoplasma.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Histoplasma capsulatum Ag:Přítomnost nebo práh:Časový bod:Tkáně a stěry:Ordinální:Imunobarvení
el-GRGreek (Greece)Histoplasma capsulatum (Ιστόπλασμα) Αντιγόνο:PrThr:Pt:Ιστός:Ord:Ανοσολογική χρώση
Synonyms: Histoplasma capsulatum (Ιστόπλασμα) MICRO Ord PrThr Pt Ανοσολογική χρώση Αντιγόνο Ιστός
es-ESSpanish (Spain)Histoplasma capsulatum Antígeno:PrThr:Punto temporal:Tejido:Ord:Tinción de inmunohistoquímica
es-MXSpanish (Mexico)Histoplasma capsulatum Ag:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Mancha inmune
et-EEEstonian (Estonia)Histoplasma capsulatum antigeen:PrThr:Pt:Tis:Ord:Immuunvärv
Synonyms: Järgarvuline Juhuslik Kude
fr-CAFrench (Canada)Histoplasma capsulatum, Ag:Présence-Seuil:Temps ponctuel:Tissu:Ordinal:Coloration immunologique
fr-FRFrench (France)Histoplasma capsulatum Ag:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Coloration immune
fr-BEFrench (Belgium)Histoplasma capsulatum Ag:PrThr:Temps ponctuel:Tissu:Ordinal:Coloration immunologique
Synonyms: Antigène Coloration. Méthode mmunologique
it-ITItalian (Italy)Histoplasma capsulatum, Ag:PrThr:Pt:Tessuto:Ord:Colorazione immunologica
Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Tessuto & Strisci
nl-NLDutch (Netherlands)Histoplasma capsulatum Ag:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunokleuring
Synonyms: antigeen
pt-BRPortuguese (Brazil)Histoplasma sp Ag:ACnc:Pt:Tecido:Ord:Imunocoloração
Synonyms: Arbitrary concentration; Point in time; Random; Tissue; Ql; Ordinal; QL; Qualitative; Qual; Screen; ImStn; Immunostain; Immunohistochemical stain; IHC; Antigen; Antigens; Imun; Imune; Imm; species; spp; Histo; Histopl; Histoplasmos; Histoplasmosis; Microbiology
ru-RURussian (Russian Federation)Histoplasma capsulatum Аг:PrThr:ТчкВрм:Тк:Пор:Иммуногистохимическая окраска
Synonyms: Порядковый Ткань и мазки Точка во времени;Момент
tr-TRTurkish (Turkey)Histoplazma Kapsulatum Ag:MevcEşik:Zmlı:Doku:Srl:İmmün boyama
Synonyms: Antijen Mevcut
zh-CNChinese (China)荚膜组织胞浆菌 抗原:存在情况或阈值:时间点:组织与涂片:序数型:免疫染色法
Synonyms: Ag 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫染色;免疫组化;免疫组化染色;免疫组化染色法;免疫组化法;免疫组织化学染色;免疫组织化学染色法;细胞免疫染色;细胞免疫染色法 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 染法 染色方法 染色法 皮疽组织胞浆菌 Ag 皮疽组织胞浆菌;美洲型组织胞浆菌;鼻疽性组织浆菌 皮疽组织胞浆菌抗原 着色 着色方法 着色法 组织胞浆菌属 组织胞浆菌病 美洲型组织胞浆菌 Ag 美洲型组织胞浆菌抗原 荚膜组织胞浆菌 Ag 鼻疽性组织浆菌 Ag 鼻疽性组织浆菌抗原

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=48338-8