48576-3

Hepatitis C virus RNA [Presence] in Specimen by Probe with signal amplification

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Part Description

LP14400-3 Hepatitis C virus
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

Fully-Specified Name

Component: Hepatitis C virus RNA
Property: PrThr
Time: Pt
System: XXX
Scale: Ord
Method: Probe.amp.sig

Additional Names

Short Name: HCV RNA Spec Ql Probe+sig amp
Display Name: HCV RNA Probe+sig amp Ql (Specimen)
Consumer Name Alpha Get Info: Hepatitis C virus (HCV), Specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.21
Last Updated: Version 2.73
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 11330

Member of these Panels

LOINC	Long Common Name
75888-8	HCV RNA screening tests - Meaningful Use set

Member of these Groups Get Info

LOINC Group	Group Name
LG32754-0	Hepatitis C virus

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	Hepatitis-C-Virus RNA:Nachweis oder Schwellenwert:Zeitpunkt:XXX:Ordinal:Sondendetektion mit Signalamplifikation Synonyms: Hepacivirus C; HCV
el-GR	Greek (Greece)	Ιός Ηπατίτιδας C RNA:PrThr:Χρονική στιγμή:ΧΧΧ:Τακτική:Ανιχνευτής με ενίσχυση σήματος
es-ES	Spanish (Spain)	Virus Hepatitis C RNA:PrThr:Punto temporal:XXX:Ord:Sonda con amplificación de señal
es-MX	Spanish (Mexico)	ARN del virus de la hepatitis C:Presencia o umbral:Punto temporal:XXX:Ordinal:Sonda con amplificación de señal
fr-CA	French (Canada)	Virus de l'hépatite C , ARN:Présence-Seuil:Temps ponctuel:XXX:Ordinal:Sonde avec amplification du signal
fr-FR	French (France)	Hépatite C virus ARN:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:PCR amplification du signal
fr-BE	French (Belgium)	Virus de l'hépatite C ARN:PrThr:Temps ponctuel:XXX:Ordinal:Sonde avec amplification du signal Synonyms: HCV
it-IT	Italian (Italy)	Epatite C, virus RNA:PrThr:Pt:XXX:Ord:Sonda.amp.sig Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del segnale Sonda di DNA Virus dell''epatite C
nl-NL	Dutch (Netherlands)	Hepatitis C-virus RNA:aanwezigheid:moment:XXX:ordinaal:probe.amp.sig
pt-BR	Portuguese (Brazil)	Hepatite C vírus RNA:ACnc:Pt:XXX:Ord:Sonda com amplificação de sinal Synonyms: Ribonucleic acid; HCV; Hep C; Arbitrary concentration; Point in time; Random; Misc; Miscellaneous; Unspecified; Other; Ql; Ordinal; QL; Qualitative; Qual; Screen; bDNA; HPA; Hybidization Protection Assay; Bdn-A; Branched Chain DNA; Hybrid Capture; Probe with signal amplification; Hybrid Capture nucleic acid hybridization; HC; Amp Prb; Probe with ampification; DNA probe; Amplification; Amplified; Hepatit; Hepatis; Microbiology
ru-RU	Russian (Russian Federation)	Гепатита С вирус РНК:PrThr:ТчкВрм:XXX:Пор:Проба.усил.сигн Synonyms: ДНК проба;ДНК зонд Порядковый Проба с сигнала усилением Точка во времени;Момент
tr-TR	Turkish (Turkey)	Hepatit C virüsü RNA:MevcEşik:Zmlı:XXX:Srl:Prob.amf.siny Synonyms: Mevcut
zh-CN	Chinese (China)	丙型肝炎病毒 RNA:存在情况或阈值:时间点:XXX:序数型:探针法.基因扩增.信号 Synonyms: C 型;丙;丙型 HCV RNA HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 Hep C RNA 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项丙肝病毒 RNA 传染性肝炎传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助信号扩增的探针方法;借助信号扩增的探针法;探针法.扩增.信号;支链 DNA;支链 DNA（Branched Chain DNA，bDNA）;杂交保护分析;杂交保护分析（Hybidization Protection Assay，HPA）;杂交保护测定;杂种捕获;杂种捕获（Hybrid Capture）;杂种捕获核酸杂交（Hybrid Capture nucleic acid hybridization）借助扩增的探针方法;借助扩增的探针法;探针法.扩增存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间核糖核酸;Ribonucleic acid 经过扩增的肝肝炎病毒 C 型 RNA 脱氧核糖核酸探针

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