LOINC
Version 2.67

48677-9Cancer Ag 125 [Presence] in Tissue by Immune stainActive

Part Description

LP14543-0   Cancer Ag 125
CA 125 is an antigenic determinant associated with a mucin-like glycoprotein, molecular weight exceeding 500,000 Daltons. This determinant is recognized by the murine monoclonal antibody OC 125, which reacts with over 80% of epithelial ovarian cancers. Elevated CA 125 levels have been reported in subjects with serous, endometrioid, clear cell, and undifferentiated ovarian carcinoma adenocarcinoma of the endometrium or fallopian tube, as well as some nongynocologic malignancies and certain nonmalignant conditions. Elevated levels also have been observed in pregnant women, most often during the first trimester. CA 125 levels may have significant value in monitoring ovarian carcinoma patients. A persistently rising CA 125 value may be associated with progressive malignant disease and poor therapeutic response. A declining CA 125 value is indicative of favorable prognosis and good response to treatment. CA 125 levels may help predict whether an invasive second-look procedure such as laparoscopy or laparotomy is required after treatment for epithelial ovarian cancer.
I.A. KOELMA, M. NAP, C.J. RODENBURG, G.J. FLEUREN (1987) The value of tumour marker CA 125 in surgical pathology
Histopathology 11 (3) , 287–294 doi:10.1111/j.1365-2559.1987.tb02633. Source: Regenstrief Institute

Fully-Specified Name

Component
Cancer Ag 125
Property
PrThr
Time
Pt
System
Tiss
Scale
Ord
Method
Immune stain

Additional Names

Short Name
Cancer Ag125 Tiss Ql ImStn
Display Name
Cancer Ag 125 Immune stain Ql (Tiss)

Basic Attributes

Class
PATH
Type
Laboratory
First Released
Version 2.21
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

zh-CNChinese (CHINA)
癌抗原 125:存在情况或阈值:时间点:组织与涂片:序数型:免疫染色法
nl-NLDutch (NETHERLANDS)
CA125:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunokleuring
et-EEEstonian (ESTONIA)
Kasvajaantigeen CA 125:PrThr:Pt:Tis:Ord:Immuunvärv
fr-BEFrench (BELGIUM)
Ag carbohydraté 125:PrThr:Temps ponctuel:Tissu:Ordinal:Coloration immunologique
fr-CAFrench (CANADA)
Ag carbohydraté 125:Présence-Seuil:Temps ponctuel:Tissu:Ordinal:Coloration immunologique
fr-FRFrench (FRANCE)
Cancer Ag 125:PrThr:Pt:Tiss:Ord:Immune stain
it-ITItalian (ITALY)
Cancro, Ag 125:PrThr:Pt:Tessuto:Ord:Colorazione immunologica
pt-BRPortuguese (BRAZIL)
Câncer Ag 125:ACnc:Pt:Tecido:Ord:Imunocoloração
ru-RURussian (RUSSIAN FEDERATION)
Раковый Аг 125:PrThr:ТчкВрм:Тк:Пор:Иммуногистохимическая окраска
es-ESSpanish (SPAIN)
Ag de cáncer 125:PrThr:Punto temporal:Tejido:Ord:Tinción de inmunohistoquímica
tr-TRTurkish (TURKEY)
Kanser Ag 125:MevcEşik:Zmlı:Doku:Srl:İmmün boyama

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=48677-9