Part Description

LP14543-0   Cancer Ag 125
CA 125 is an antigenic determinant associated with a mucin-like glycoprotein, molecular weight exceeding 500,000 Daltons. This determinant is recognized by the murine monoclonal antibody OC 125, which reacts with over 80% of epithelial ovarian cancers. Elevated CA 125 levels have been reported in subjects with serous, endometrioid, clear cell, and undifferentiated ovarian carcinoma adenocarcinoma of the endometrium or fallopian tube, as well as some nongynocologic malignancies and certain nonmalignant conditions. Elevated levels also have been observed in pregnant women, most often during the first trimester. CA 125 levels may have significant value in monitoring ovarian carcinoma patients. A persistently rising CA 125 value may be associated with progressive malignant disease and poor therapeutic response. A declining CA 125 value is indicative of favorable prognosis and good response to treatment. CA 125 levels may help predict whether an invasive second-look procedure such as laparoscopy or laparotomy is required after treatment for epithelial ovarian cancer.
I.A. KOELMA, M. NAP, C.J. RODENBURG, G.J. FLEUREN (1987) The value of tumour marker CA 125 in surgical pathology
Histopathology 11 (3) , 287-294 doi:10.1111/j.1365-2559.1987.tb02633. Source: Regenstrief Institute

LOINC Names Get Info

Fully-Specified Name
Cancer Ag 125:PrThr:Pt:Tiss:Ord:Immune stain
Long Common Name
Cancer Ag 125 [Presence] in Tissue by Immune stain
Short Name
Cancer Ag125 Tiss Ql ImStn
Display Name
Cancer Ag 125 Immune stain Ql (Tiss)
Consumer Name Alpha Get Info
Cancer Ag 125, Tissue

Part Model Get Info

  • Component
    Cancer Ag 125
    LP14543-0
    • Analyte
      Cancer Ag 125
      LP14543-0
      • Component Numerator
        Cancer Ag 125
        LP14543-0
        • Component Numerator Core
          Cancer Ag 125
          LP14543-0
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Tiss
    LP7641-6
    • System Core
      Tiss
      LP7641-6
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Immune stain
    LP6333-1

Basic Attributes

Class
PATH
Type
Laboratory
First Released
Version 2.21
Last Updated
Version 2.73 (MIN)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
13815

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Cancer Ag 125:Přítomnost nebo práh:Časový bod:Tkáně a stěry:Ordinální:Imunobarvení
el-GRGreek (Greece)Καρκινικό αντιγόνο 125:PrThr:Pt:Ιστός:Ord:Ανοσολογική χρώση
Synonyms: Ord PATH PrThr Pt Ανοσολογική χρώση Ιστός Καρκινικό αντιγόνο 125 Καρκίνος
es-MXSpanish (Mexico)Cáncer Ag 125:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Mancha inmune
es-ESSpanish (Spain)Ag de cáncer 125:PrThr:Punto temporal:Tejido:Ord:Tinción de inmunohistoquímica
et-EEEstonian (Estonia)Kasvajaantigeen CA 125:PrThr:Pt:Tis:Ord:Immuunvärv
Synonyms: Järgarvuline Juhuslik Kude
fr-CAFrench (Canada)Ag carbohydraté 125:Présence-Seuil:Temps ponctuel:Tissu:Ordinal:Coloration immunologique
fr-FRFrench (France)Carbohydrate antigène 125:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Coloration immune
fr-BEFrench (Belgium)Ag carbohydraté 125:PrThr:Temps ponctuel:Tissu:Ordinal:Coloration immunologique
Synonyms: Ca 125 Coloration. Méthode mmunologique
it-ITItalian (Italy)Cancro, Ag 125:PrThr:Pt:Tessuto:Ord:Colorazione immunologica
Synonyms: Antigene 125 di cancro Patologia Presenza o Soglia Punto nel tempo (episodio) Tessuto & Strisci
nl-NLDutch (Netherlands)CA125:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunokleuring
Synonyms: kanker Ag 125
pl-PLPolish (Poland)CA 125 Ag:granica wykrywalności:punkt w czasie:tkanka i rozmazy:uporządkowany:barwienie immunohistochemiczne
Synonyms: Antygen CA 125
pt-BRPortuguese (Brazil)Câncer Ag 125:ACnc:Pt:Tecido:Ord:Imunocoloração
Synonyms: ; Cancer Ag125; OC125; CA 125; Cancer antigen 125; Arbitrary concentration; Point in time; Random; Tissue; Ql; Ordinal; QL; Qualitative; Qual; Screen; ImStn; Immunostain; Immunohistochemical stain; IHC; Antigen; Antigens; Imun; Imune; Imm; PATHOLOGY
ru-RURussian (Russian Federation)Раковый Аг 125:PrThr:ТчкВрм:Тк:Пор:Иммуногистохимическая окраска
Synonyms: Порядковый Ткань и мазки Точка во времени;Момент
tr-TRTurkish (Turkey)Kanser Ag 125:MevcEşik:Zmlı:Doku:Srl:İmmün boyama
Synonyms: Mevcut
zh-CNChinese (China)癌抗原 125:存在情况或阈值:时间点:组织与涂片:序数型:免疫染色法
Synonyms: CA CA 125;OC125;癌 Ag 125;癌抗原 125(Cancer Antigen 125,CA 125) 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫染色;免疫组化;免疫组化染色;免疫组化染色法;免疫组化法;免疫组织化学染色;免疫组织化学染色法;细胞免疫染色;细胞免疫染色法 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 染法 染色方法 染色法 癌 癌 Ag 癌症抗原 着色 着色方法 着色法

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=48677-9