49230-6
Acetylcholinesterase [Enzymatic activity/mass] in Red Blood Cells
Active
Term Description
Used in diagnosis of pesticide toxicity or succinylcholine toxicity. Also used to evaluate paroxysmal nocturnal hemoglobinuria. Cholinesterase activity is completely and irreversibly inhibited by organophosphate containing pesticides.
Source: Regenstrief LOINC
Part Descriptions
LP15315-2 Acetylcholinesterase
An enzyme that catalyzes the hydrolysis of ACETYLCHOLINE to CHOLINE and acetate. In the CNS, this enzyme plays a role in the function of peripheral neuromuscular junctions. EC 3.1.1.7.
Source: National Library of Medicine, MeSH 2006
LP15315-2 Acetylcholinesterase
Acetylcholinesterase, an enyzme (EC 3.1.1.7) (AChE) that controls synaptic and neurohumoral cholinergic activity by hydrolyzing the neurotransmitter acetylcholine, is also known as RBC cholinesterase, erythrocyte cholinesterase, or (most formally) acetylcholine acetylhydrolase. The ACHE gene is mapped to chromosome 7q22. AChE is found primarily in the blood on red blood cell membranes, in neuromuscular junctions, and in neural synapses. Two main clinical diagnostic uses are: 1) a second trimester screening test for fetal neural tube defects using amniotic fluid and, 2) in the general population, to detect past exposure to organophosphate insecticides with resultant inhibition of the enzyme using blood.
Source: Regenstrief LOINC, Acetylcholinesterase
Fully-Specified Name
- Component
- Acetylcholinesterase
- Property
- CCnt
- Time
- Pt
- System
- RBC
- Scale
- Qn
- Method
Additional Names
- Short Name
- AChE RBC-cCnt
- Display Name
- Acetylcholinesterase (RBC) [Catalytic activity/Mass]
- Consumer Name Alpha Get Info
- Acetylcholinesterase, Red blood cells
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.21
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 8612
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Acetilcolinesterasa: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Acetilcolinesterasa: |
| et-EE | Estonian (Estonia) | Atsetüülkoliini esteraas: Synonyms: Erütrotsüüdid Juhuslik Kvantitatiivne |
| fr-CA | French (Canada) | Acétylcholinestérase: |
| fr-FR | French (France) | Acétylcholinestérase: |
| fr-BE | French (Belgium) | Acétylcholinestérase: |
| it-IT | Italian (Italy) | Acetilcolinesterasi: Synonyms: Chimica Contenuto Catalitico Globuli rossi Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | acetylcholinesterase: Synonyms: rode bloedcellen |
| pt-BR | Portuguese (Brazil) | Acetilcolinesterase: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Ацетилхолинэстераза: Synonyms: Каталитическое содержание Количественный Точка во времени; |
| tr-TR | Turkish (Turkey) | Asetilkolinesteraz: Synonyms: RBC |
| uk-UA | Ukrainian (Ukraine) | Ацетилхолінестераза: Synonyms: Acetycholinesterase; |
| zh-CN | Chinese (China) | 乙酰胆碱酯酶: Synonyms: AChE; |
Example Units
| Unit | Source |
|---|---|
| U/g Hgb | REGENSTRIEF |
| U/g{Hb} | Example UCUM Units |
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