LOINC
Version 2.73

49536-6Influenza virus B RNA [Identifier] in Isolate by SequencingDiscouraged

Status Information

Status
Discouraged
Comment
Awaiting more information about usage of this term.

Part Descriptions

LP14240-3   Influenza virus B
Influenza virus from the family Orthomyxoviridae are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C viruses are medically relevant to humans. Influenza A and B viruses have a similar structure whereby these viruses each contain eight discrete single-stranded RNA gene segments, each encoding at least one protein. While having a close phylogenetic relationship, influenza virus types A and B manifest very differently. While IAV infects birds, humans and other mammals, influenza B only infects humans and seals. Although both viruses cause human respiratory infection seasonally in temperate climate regions and more continually in the tropics, influenza B is normally less prevalent and causes less severe disease than IAV viruses. Research is ongoing to determine the evolutionary and epidemiological factors that shape the genetic diversity of influenza B virus. [PMID:25812763] [CDC:flu/about/viruses/types] Source: Regenstrief LOINC

LP150045-5   Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977.[PMID:271968] Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost.[PMID:18576944] Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template.[PMID:20858600] Source: Regenstrief LOINC, B blood group

Fully-Specified Name

Component
Influenza virus B RNA
Property
Prid
Time
Pt
System
Isolate
Scale
Nom
Method
Sequencing

Additional Names

Short Name
FLUBV RNA Islt Seq
Display Name
FLUBV RNA Sequencing Nom (Isol)
Consumer Name Alpha
Influenza B (Flu B)

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.22
Last Updated
Version 2.40
Change Reason
Changed method from Amplification/Sequencing because Amplification always occurs before sequencing
Order vs. Observation
Both

Member of these Groups

LG32757-3 Influenza virus

Language Variants Get Info

zh-CNChinese (China)
流感病毒 B 型 RNA:存在与否或特征标识:时间点:分离株:名义型:序列测定
nl-NLDutch (Netherlands)
Influenzavirus B RNA:identificator:moment:isolaat:nominaal:sequencing
fr-BEFrench (Belgium)
Virus de l'influenza B ARN:Présence ou identité:Temps ponctuel:Isolat:Nominal:Séquençage
fr-CAFrench (Canada)
Virus de l'influenza B , ARN:Présence ou identité:Temps ponctuel:Isolat:Nominal:Séquençage
de-DEGerman (Germany)
Influenza-Virus B RNA:Nachweis oder Identität:Zeitpunkt:Isolat:Nominal:Sequenzierung
it-ITItalian (Italy)
Influenza B, virus RNA:Prid:Pt:Isolato:Nom:Sequenziamento
pt-BRPortuguese (Brazil)
Influenza vírus B cDNA:Ident:Pt:Isolado:Nom:Amplificação/sequenciamento
es-MXSpanish (Mexico)
ARN del virus de la influenza B:Presencia o identidad:Punto temporal:Aislado:Nominal:Secuenciación
es-ESSpanish (Spain)
Virus Influenza B RNA:Presencia o identidad:Punto temporal:Aislado:Nom:Secuenciación
tr-TRTurkish (Turkey)
İnfluenza virüsü B RNA:MevcKimlik:Zmlı:İzolat:Snf:Sekanslama

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=49536-6