49747-9
Cocaine+Benzoylecgonine [Presence] in Serum or Plasma by Screen method
Active
Part Descriptions
LP36028-6 Cocaine+Benzoylecgonine
Cocaine is an alkaloid of Erythroxylon coca that is grown in the northern South American Andes, India, Africa and Java. It is used medicinally as a local anesthetic and vasoconstrictor in nasal surgery and to dilate pupils. Because cocaine is a powerful central nervous system stimulant it is among the most abused drugs. Cocaine abuse can lead to sudden death due to cardiotoxicity or the sequential development of hyperthermia, agitated delirium and respiratory arrest. Cocaine is metabolized in the liver to inactive benzoylecgonine (BZE). BZE is pharmacologically inactive and has a longer half-life than its parent drug cocaine. It is the substance most tested for when investigating suspected cocaine abuse. Cocaethylene (CE) is produced in the liver in the presence of ethanol and has been shown to have similar stimulatory effects as cocaine in animal studies.(Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, Seventh Edition) Cocaethylene is toxic to the myocardium. PMID: 8761012
Source: Regenstrief LOINC
LP36028-6 Cocaine+Benzoylecgonine
Benzoylecgonine is the major metabolite of cocaine. It is a biological metabolite with a stable structure that resists hydrolysis, both in the body and in the environment. Benzoylecgonine remains in the body for a few days and is commonly used as a marker in drug tests. [PMCID:1929267] PMID: 27224254
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Cocaine+Benzoylecgonine
- Property
- PrThr
- Time
- Pt
- System
- Ser/Plas
- Scale
- Ord
- Method
- Screen
Additional Names
- Long Common Name
- Cocaine+Benzoylecgonine [Presence] in Serum or Plasma by Screen method
- Short Name
- Cocaine+BZE SerPl Ql Scn
- Display Name
- Cocaine+Benzoylecgonine Screen Ql
- Consumer Name Alpha Get Info
- Cocaine+Benzoylecgonine, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.22
- Last Updated
- Version 2.73
- Change Reason
- The Property has been changed from ACnc to reflect new model for ordinal terms; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 5402
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG50145-8 | Cocaine+Benzoylecgonine| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: BZG/Cocain ql. |
es-ES | Spanish (Spain) | Cocaina+Benzoilecgonina: |
es-MX | Spanish (Mexico) | Cocaína + Benzoilecgonina: |
fr-CA | French (Canada) | Cocaïne+Benzoylecgonine: |
fr-FR | French (France) | Cocaïne+benzoylecgonine: |
fr-BE | French (Belgium) | Cocaïne+Benzoylecgonine: |
it-IT | Italian (Italy) | Cocaina+Benzoilecgonina: Synonyms: Livelli farmacologici e tossicologia Plasma Presenza o Soglia Punto nel tempo (episodio) Screening tossicologico Siero Siero o Plasma |
nl-NL | Dutch (Netherlands) | cocaïne + benzoylecgonine: |
pt-BR | Portuguese (Brazil) | Cocaína+Benzoilecgonina: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Кокаин+Бензоилэкгонин: Synonyms: Плазма Порядковый Сыворотка Сыворотка или Плазма Токсикологический скрининг Точка во времени; |
tr-TR | Turkish (Turkey) | Kokain+Benzoilekgonin: Synonyms: Mevcut |
zh-CN | Chinese (China) | 可卡因+苯甲酰芽子碱: Synonyms: C17H21NO4; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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LOINC Copyright
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