49823-8
3-Hydroxyisovalerate/Creatinine [Molar ratio] in 24 hour Urine
Active
Part Descriptions
LP15301-2 3-Hydroxyisovalerate
3-Hydroxyisovaleric acid is a normal human metabolite excreted in the urine. Elevated levels of this compound are found in several inherited disorders such as Dihydrolipoamide dehydrogenase Deficiency, 3-Methylcrotonyl-CoA carboxylase 1 deficiency, 3-Hydroxy-3-methylglutaryl-CoA lyase deficiency (3-hydroxy-3-methylglutaryl -CoA lyase Deficiency, Biotinidase deficiency multiple carboxylase deficiency late-onset , Late onset multiple carboxylase deficiency, HolMcarboxylase synthetase deficiency, 3-Methylcrotonyl-CoA carboxylase 2 deficiency. 3-Hydroxyisovaleric acid is also elevated in smokers, in subjects undergoing long-term anticonvulsant therapy with carbamazepine and/or phenytoin. These levels are elevated due to impairment of renal reclamation of biotin. Levels may also be increased from prolonged consumption of raw egg-whites PMID: 16895887, PMID: 9523856, PMID: 15447901, PMID: 9176832, [OMIM: 210210], [OMIM: 253270], [OMIM: 600529], [OMIM: 253260], [OMIM: 246450], [OMIM: 210200], [OMIM: 238331]
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database,
Human Metabolome Database
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database,
Creatinine
LOINC Names Get Info
- Fully-Specified Name
- 3-Hydroxyisovalerate/Creatinine:
SRto: 24H: Urine: Qn: - Long Common Name
- 3-Hydroxyisovalerate/Creatinine [Molar ratio] in 24 hour Urine
- Short Name
- 3OH-Isovalerate/Creat 24h Ur-sRto
- Display Name
- 3-Hydroxyisovalerate/Creatinine (24H U) [Molar ratio]
- Consumer Name Alpha Get Info
- 3-Hydroxyisovalerate/Creatinine, Urine
Part Model Get Info
- Component
- 3-Hydroxyisovalerate/Creatinine
LP284754-1
- Analyte
- 3-Hydroxyisovalerate/Creatinine
LP284754-1
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- SRto
LP6868-6
- Time
- 24H
LP6924-7
- Time Core
- 24H
LP6924-7
- Time Modifier
- NULL
- System
- Urine
LP7681-2
- System Core
- Urine
LP7681-2
- Super System
- NULL
- Scale
- Qn
LP7753-9
- Method
- NULL
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.22
- Last Updated
- Version 2.42 (MIN)
- Order vs. Observation
- Observation
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG35772-9 | 3-Hydroxyisovalerate/Creatinine| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | 3-hydroxyizovalerát/kreatinin: |
| de-AT | German (Austria) | Synonyms: 3-OH-Isovaleriansäure/Kreatinin-Ratio /24hU |
| de-DE | German (Germany) | 3-Hydroxyisovalerat/Creatinin: |
| el-GR | Greek (Greece) | 3-υδροξυϊσοβαλεριανικό/Κρεατινίνη: Synonyms: 24H 3-υδροξυϊσοβαλεριανικό CHEM Qn SRto Κρεατινίνη Ούρα |
| es-ES | Spanish (Spain) | 3-Hidroxiisovalerato/Creatinina: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | 3-hidroxiisovalerato / creatinina: |
| fr-CA | French (Canada) | 3-hydroxyisovalérate/Créatinine: |
| fr-FR | French (France) | 3-hydroxyisovalérate/créatinine: |
| fr-BE | French (Belgium) | 3-hydroxyisovalérate/Créatinine: |
| it-IT | Italian (Italy) | 3-Idrossiisovalerato/Creatinina: Synonyms: 24 Ore Chimica Rapporto di sostanza |
| nl-NL | Dutch (Netherlands) | 3-hydroxyisovaleraat/creatinine: Synonyms: 24U kreatinine |
| pl-PL | Polish (Poland) | 3-Hydroksyizowalerian/kreatynina: Synonyms: 24 godziny |
| pt-BR | Portuguese (Brazil) | 3-Hidroxiisovalerato/Creatinina: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | 3-Гидроксиизовалерат/Креатинин: Synonyms: Количественный Мольная доля; |
| tr-TR | Turkish (Turkey) | 3-Hidroksiizovalerat/Kreatinin: Synonyms: SubsOranı |
| zh-CN | Chinese (China) | 3-羟基异戊酸/肌酐: Synonyms: 1天; |
Example Units
| Unit | Source |
|---|---|
| mmol/mol{creat} | Example UCUM Units |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://