Version 2.78

Part Descriptions

LP207365-0   Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP21134-9   Powassan virus
The Powassan virus is a tick-borne encephalitis virus related to the classic TBE flavivirus. This disease had its earliest origins in the town of Powassan, Ontario, found in a young boy who eventually died from it. Powassan virus is transmitted by I.cookei among small mammals in eastern Canada and the United States, where it has been responsible for 20 recognized cases of human disease. Other ticks may transmit the virus in a wider geographic area, and there is some concern that I.scapularis (also called I.dammini ), a competent vector in the laboratory, may become involved as it becomes more prominent in the United States. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Powassan virus

LP6416-4   Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

Fully-Specified Name

Component
Powassan virus Ab.Neut
Property
PrThr
Time
Pt
System
XXX
Scale
Ord
Method
Neut

Additional Names

Short Name
POWV NAb Spec Ql Nt
Display Name
Powassan virus neut ab Neut test Ql (Specimen)
Consumer Name Alpha Get Info
Powassan virus neutralizing antibody, Specimen

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.22
Last Updated
Version 2.72
Change Reason
Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.; Previous Releases: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG32767-2 Powassan virus

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Virus Powassan Anticuerpos antineutrófilos:PrThr:Punto temporal:XXX:Ord:Prueba de neutralización
es-MX Spanish (Mexico) Virus de Powassan Ab:Presencia o umbral:Punto temporal:XXX:Ordinal:Prueba de neutralización
fr-FR French (France) Powassan virus Ac neutralisant:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:Neutralisation
fr-CA French (Canada) Virus Powassan Ac.neut:Présence-Seuil:Temps ponctuel:XXX:Ordinal:Test de neutralisation
it-IT Italian (Italy) Powassan, virus Ab.Neut:PrThr:Pt:XXX:Ord:Neut
Synonyms: anticorpo Microbiologia Presenza o Soglia Punto nel tempo (episodio) Test di neutralizzazione Virus dell''encefalite Powassan
nl-NL Dutch (Netherlands) Powassanvirus As.neutraliserend:aanwezigheid:moment:XXX:ordinaal:neutralisatietest
Synonyms: antistof; antilichaam
pl-PL Polish (Poland) Wirus Powassan Ab.Neutralizujące:granica wykrywalności:punkt w czasie:XXX:półilościowy:test neutralizacji
Synonyms: Przeciwciała do wirusa Powassan Przeciwciała neutralizujące do wirusa Powassan
pt-BR Portuguese (Brazil) Powassan vírus Ac:ACnc:Pt:XXX:Ord:Teste de neutralização
Synonyms: ; POWV; Arbitrary concentration; Point in time; Random; Misc; Miscellaneous; Unspecified; Other; Ql; Ordinal; QL; Qualitative; Qual; Screen; Nt; NT; Neutralization test; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
zh-CN Chinese (China) Powassan 病毒 抗体.中和:存在情况或阈值:时间点:XXX:序数型:中和试验
Synonyms: Ab;自身抗体 Powassan 病毒 Ab POWV POWV Ab POWV 抗体 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 中和试验;中和抗体;中和 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=50037-1