5012-0

Hepatitis C virus RNA [Presence] in Specimen by NAA with probe detection

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Part Description

LP14400-3 Hepatitis C virus
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

Fully-Specified Name

Component: Hepatitis C virus RNA
Property: PrThr
Time: Pt
System: XXX
Scale: Ord
Method: Probe.amp.tar

Additional Names

Short Name: HCV RNA Spec Ql NAA+probe
Display Name: HCV RNA NAA+probe Ql (Specimen)
Consumer Name Alpha Get Info: Hepatitis C virus (HCV), Specimen

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 1.0
Last Updated: Version 2.73
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 4127

Member of these Panels

LOINC	Long Common Name
75888-8	HCV RNA screening tests - Meaningful Use set

Member of these Groups Get Info

LOINC Group	Group Name
LG32754-0	Hepatitis C virus

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	Hepatitis-C-Virus RNA:Nachweis oder Schwellenwert:Zeitpunkt:XXX:Ordinal:Zielfragmentamplifikation mit Sondendetektion Synonyms: Hepacivirus C; HCV
el-GR	Greek (Greece)	Ιός Ηπατίτιδας C RNA:PrThr:Χρονική στιγμή:ΧΧΧ:Τακτική:Ανιχνευτής με ενίσχυση στόχου
es-AR	Spanish (Argentina)	ARN del virus de la hepatitis C:concentración arbitraria:punto en el tiempo:XXX:ordinal:sonda.amplificación.blanco
es-ES	Spanish (Spain)	Virus Hepatitis C RNA:PrThr:Punto temporal:XXX:Ord:Sonda con amplificación dirigida
es-MX	Spanish (Mexico)	ARN del virus de la hepatitis C:Presencia o umbral:Punto temporal:XXX:Ordinal:Amplificación de ácidos nucleicos con detección de sonda
fr-CA	French (Canada)	Virus de l'hépatite C ARN:Présence-Seuil:Temps ponctuel:XXX:Ordinal:Sonde avec amplification de la cible
fr-FR	French (France)	Hépatite C virus ARN:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:PCR amplification de cible
fr-BE	French (Belgium)	Virus de l'hépatite C ARN:PrThr:Temps ponctuel:XXX:Ordinal:Sonde avec amplification de la cible Synonyms: HCV
it-IT	Italian (Italy)	Epatite C, virus RNA:PrThr:Pt:XXX:Ord:Sonda.amp.tar Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''epatite C
ko-KR	Korean (Korea, Republic Of)	C형 간염 바이러스 리보핵산:임의농도:검사시점:XXX:순위척도:DNA 탐색자.증폭.표적
nl-NL	Dutch (Netherlands)	Hepatitis C-virus RNA:aanwezigheid:moment:XXX:ordinaal:probe-detectie Synonyms: probe.amp.tar
pt-BR	Portuguese (Brazil)	Hepatite C vírus RNA:ACnc:Pt:XXX:Ord:Sonda com limite de detecção da amplificação de alvo Synonyms: Ribonucleic acid; HCV; Hep C; Arbitrary concentration; Point in time; Random; Misc; Miscellaneous; Unspecified; Other; Ql; Ordinal; QL; Qualitative; Qual; Screen; PCR; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Amplified; Hepatit; Hepatis; Microbiology
ru-RU	Russian (Russian Federation)	Гепатита С вирус РНК:PrThr:ТчкВрм:XXX:Пор:Проба.усил.миш Synonyms: ДНК проба;ДНК зонд Порядковый Проба с мишени усилением Точка во времени;Момент
tr-TR	Turkish (Turkey)	Hepatit C virüsü RNA:MevcEşik:Zmlı:XXX:Srl:Prob.amf.hdf Synonyms: Mevcut
zh-CN	Chinese (China)	丙型肝炎病毒 RNA:存在情况或阈值:时间点:XXX:序数型:探针法.基因扩增.靶向 Synonyms: C 型;丙;丙型 HCV RNA HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 Hep C RNA 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项丙肝病毒 RNA 传染性肝炎传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性时刻;随机;随意;瞬间核糖核酸;Ribonucleic acid 经过扩增的肝肝炎病毒 C 型 RNA 脱氧核糖核酸探针

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.