LOINC
Version 2.66

5048-4Nuclear Ab [Titer] in Serum by ImmunofluorescenceActive

Component
Nuclear Ab
Property
Titr
Time
Pt
System
Ser
Scale
Qn
Method
IF

Additional Names

Short Name
ANA Titr Ser IF
Display Name Beta
Nuclear Ab IF (S) [Titer]
Consumer Name Alpha
Nuclear Antibody, Blood

Part Descriptions

LP16670-9   Nuclear
The nucleus of a cell contains the body's genetic material. It is the site of transcriptional regulation, RNA processing and DNA synthesis and transcription.
[PMID: 24563360] Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, Anti-nuclear antibodies

LP20752-9   Nuclear Ab
Anti-nuclear antibodies (ANAs), also known as anti-nuclear factor or ANF, are auto-antibodies directed against contents of the cell nucleus. They are present in low numbers in the general population but higher than normal amounts in autoimmune diseases, including lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, scleroderma, and autoimmune hepatitis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Anti-nuclear antibodies

LP20752-9   Nuclear Ab
Anti-nuclear antibodies (ANAs, also known as anti-nuclear factor or ANF) are autoantibodies directed against contents of the cell nucleus. They are present in higher than normal numbers in autoimmune disease. The ANA test measures the pattern and amount of autoantibody which can attack the body's tissues as if they were foreign material. Autoantibodies are present in low titers in the general population, but in about 5% of the population, their concentration is increased, and about half of this 5% have an autoimmune disease.

The presence of ANA is indicative of lupus erythematosus (present in 80-90% of cases), though they also appear in some other auto-immune diseases such as[citation needed] Sjögren's syndrome (60%), rheumatoid arthritis (30-40%), autoimmune hepatitis, scleroderma and polymyositis & dermatomyositis (30%), and various non-rheumatological conditions associated with tissue damage. Other conditions with high ANA titre include Addison disease, Idiopathic thrombocytopenic purpura (ITP), Hashimoto's, Autoimmune hemolytic anemia, Type I diabetes mellitus, Mixed connective tissue disorder. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.38
Order vs. Observation
Both
Common US Lab Results Rank
345
Common SI Lab Results Rank
345

Member of these Groups

LG7004-7 Nuclear Ab|Titr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
细胞核 抗体:滴定度:时间点:血清:定量型:免疫荧光法
nl-NLDutch (Netherlands)
nucleaire As:titer:moment:serum:kwantitatief:immunofluorescentie
et-EEEstonian (Estonia)
Tuumavastased antikehad:Titr:Pt:S:Qn:IF
fr-BEFrench (Belgium)
Nucléaire Ac:Titre:Temps ponctuel:Sérum:Quantitatif:Immunofluorescence
fr-CAFrench (Canada)
Nucléaire , Ac:Titre:Temps ponctuel:Sérum:Quantitatif:Immunofluorescence
fr-FRFrench (France)
Nuclear Ab:Titr:Pt:Ser:Qn:IF
fr-CHFrench (Switzerland)
S--noyau cellulaire, Ig; ; IF
de-ATGerman (Austria)
ANA Titer IF
de-DEGerman (Germany)
Nukleärer Ak:Titr:Pkt:Ser:Qn:IF
de-CHGerman (Switzerland)
S--Zellkern, Ig; ; IF
it-ITItalian (Italy)
Nucleare , Ab:Titr:Pt:Siero:Qn:IF
it-CHItalian (Switzerland)
S--nucleo cellulare, Ig; ; IF
ko-KRKorean (Korea, Republic of)
핵 항체:역가:검사시점:혈청:정량:면역형광
pt-BRPortuguese (Brazil)
Nuclear Ac:Título:Pt:Soro:Qn:Imunofluorescência
ru-RURussian (Russian Federation)
Ядерный Ат:Титр:ТчкВрм:Сыв:Колич:ИФ
es-ARSpanish (Argentina)
[anticuerpo] antinuclear [Ac]:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:inmunofluorescencia
es-ESSpanish (Spain)
Nuclear Anticuerpos:Titulo / Factor de dilución:Punto temporal:Suero:Qn:Inmunofluorescencia (IF)
es-CHSpanish (Switzerland)
S--núcleo celular, Ig; ; IF
tr-TRTurkish (Turkey)
Nükleer Ab:Titr:Zmlı:Ser:Kant:IF

Example Units

Unit Source
{titer} Example UCUM Units
titer Original Submission
titer REGENSTRIEF

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=5048-4