5101-1

Coxsackievirus A7 neutralizing antibody [Titer] in Serum by Neutralization test

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Part Descriptions

LP14247-8 Coxsackievirus A7
Coxsackievirus A7 (CVA7) is a rarely detected and poorly characterized virus that belongs to the Enterovirus A species and has three strains: Parker, USSR, and 275/58. Despite a difference in pathogenicity among the three strains, they can all be typed by CVA7-specific neutralizing antibodies. CVA7 is most closely related to CVA14, CVA16, and Enterovirus 71 (EV71), and is associated with hand, foot and mouth disease (HFMD). CVA7 is neurotropic and can cause paralytic poliomyelitis. CVA7 was widely detected in the 1950s and 1960s during paralytic epidemics. PMID: 22438546 PMID: 22514349 Source: Regenstrief LOINC

LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Coxsackievirus A7 Ab.Neut:Titr:Pt:Ser:SemiQn:Neut
Long Common Name: Coxsackievirus A7 neutralizing antibody [Titer] in Serum by Neutralization test
Short Name: CV A7 NAb Titr Ser Nt
Display Name: Coxsackievirus A7 neut ab Neut test (S) [Titer]
Consumer Name Alpha Get Info: Coxsackievirus A7 neutralizing antibody, Blood

Part Model Get Info

Component
Coxsackievirus A7 Ab.Neut
LP430343-6
- Analyte
  Coxsackievirus A7 Ab.Neut
  LP430343-6
  - Component Numerator
    Coxsackievirus A7 Ab.Neut
    LP430343-6
    - Component Numerator Core
      Coxsackievirus A7
      LP14247-8
    - Component Numerator Core Suffix
      Ab.Neut
      LP207365-0
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Titr
LP6881-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
SemiQn
LP436123-6
Method
Neut
LP6416-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 1.0
Last Updated: Version 2.75 (MAJ)
Change Reason: Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Coxsackievirus A7 Ab.neutralizační:Arbitrární koncentrace (titr):Časový bod:Sérum:Semikvantitativní:Neutralizační test
de-DE	German (Germany)	Coxsackie-Virus A7 Ak.neutralisierend:Titer:Zeitpunkt:Serum:Semiquantitativ:Neutralisationstest
el-GR	Greek (Greece)	Ιός Κοξάκι A7 Ab.Neut:Titr:Pt:Ορός:Ημιποσοτική:Ουδετερόφιλα Synonyms: Ab.Neut MICRO Pt Titr Αντίσωμα Ημιποσοτική Ιός Κοξάκι Ιός Κοξάκι A7 Ορός Ουδετερόφιλα
es-AR	Spanish (Argentina)	[anticuerpo anti - ] virus Coxsackie A7 [Ac]:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:neutralización
es-ES	Spanish (Spain)	Virus Coxsackie A7 Anticuerpos antineutrófilos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:Prueba de neutralización Synonyms: Semicuantitativo
es-MX	Spanish (Mexico)	Coxsackievirus A7 Ab:Título:Punto temporal:Suero:Cuantitativo:Prueba de neutralización
fr-CA	French (Canada)	Coxsackievirus A7 Ac.neut:Titre:Temps ponctuel:Sérum:SemiQn:Test de neutralisation
fr-FR	French (France)	Coxsackievirus A7 Ac neutralisant:Titre:Ponctuel:Sérum:Semi-Quantitatif:Neutralisation
it-IT	Italian (Italy)	Coxsackievirus A7 Ab.Neut:Titr:Pt:Siero:SemiQn:Neut Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Siero Test di neutralizzazione Titolo
ko-KR	Korean (Korea, Republic Of)	콕사키바이러스 A1 항체:역가:검사시점:혈청:정량:중화
nl-NL	Dutch (Netherlands)	Coxsackievirus A7 As.neutraliserend:titer:moment:serum:semikwantitatief:neutralisatietest Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Wirus Coxsackie A7 Ab.Neutralizujące:miano:punkt w czasie:surowica:półilościowy:test neutralizacji Synonyms: Przecwiciała do wirusa Coxsackie A7 Przecwiciała neutralizujące do wirusa Coxsackie A7 Wirus Coxsackie Wirus Coxsackie A7
pt-BR	Portuguese (Brazil)	Coxsackie vírus A7 Ac:Título:Pt:Soro:Qn:Teste de neutralização Synonyms: ; CV A7; Coxsackie; Coxsackie virus; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Nt; NT; Neutralization test; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
zh-CN	Chinese (China)	柯萨奇病毒 A7 型抗体.中和:滴定度:时间点:血清:半定量型:中和试验 Synonyms: Ab;自身抗体 Coxsackie;CV;柯萨基病毒;考克塞基病毒 CV A7 Ab CV A7 型 Ab CV A7 型抗体 CV A7 抗体 CV A7;CV A7 型;柯萨基病毒 A7 型;考克塞基病毒 A7 型中和试验;中和抗体;中和微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数时刻;随机;随意;瞬间柯萨基病毒 A7 型 Ab 柯萨基病毒 A7 型抗体柯萨奇病毒 A7 型 Ab 考克塞基病毒 A7 型 Ab 考克塞基病毒 A7 型抗体

Example Units

Unit	Source
{titer}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.