5103-7

Coxsackievirus B1 neutralizing antibody [Titer] in Serum by Neutralization test

Active

Part Descriptions

LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Coxsackievirus B1 Ab.Neut:Titr:Pt:Ser:SemiQn:Neut
Long Common Name: Coxsackievirus B1 neutralizing antibody [Titer] in Serum by Neutralization test
Short Name: CV B1 NAb Titr Ser Nt
Display Name: Coxsackievirus B1 neut ab Neut test (S) [Titer]
Consumer Name Alpha Get Info: Coxsackievirus B1 neutralizing antibody, Blood

Part Model Get Info

Component
Coxsackievirus B1 Ab.Neut
LP430345-1
- Analyte
  Coxsackievirus B1 Ab.Neut
  LP430345-1
  - Component Numerator
    Coxsackievirus B1 Ab.Neut
    LP430345-1
    - Component Numerator Core
      Coxsackievirus B1
      LP14062-1
    - Component Numerator Core Suffix
      Ab.Neut
      LP207365-0
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Titr
LP6881-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
SemiQn
LP436123-6
Method
Neut
LP6416-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 1.0
Last Updated: Version 2.75 (MAJ)
Change Reason: Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
Order vs. Observation: Both
Common Test Rank Get Info: 6804

Member of these Panels

LOINC	Long Common Name
41486-2	Coxsackievirus B neutralizing Ab panel [Titer] - Serum by Neutralization test

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Coxsackievirus B1 Ab.neutralizační:Arbitrární koncentrace (titr):Časový bod:Sérum:Semikvantitativní:Neutralizační test
de-DE	German (Germany)	Coxsackie-Virus B1 Ak.neutralisierend:Titer:Zeitpunkt:Serum:Semiquantitativ:Neutralisationstest
el-GR	Greek (Greece)	Ιός Κοξάκι B1 Ab.Neut:Titr:Pt:Ορός:Ημιποσοτική:Ουδετερόφιλα Synonyms: Ab.Neut MICRO Pt Titr Αντίσωμα Ημιποσοτική Ιός Κοξάκι Ιός Κοξάκι B1 Ορός Ουδετερόφιλα
es-AR	Spanish (Argentina)	[anticuerpo anti - ] virus Coxsackie B1 [Ac]:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:neutralización
es-ES	Spanish (Spain)	Coxsackievirus B1 Anticuerpos antineutrófilos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:Prueba de neutralización Synonyms: Semicuantitativo
es-MX	Spanish (Mexico)	Coxsackievirus B1 Ab:Título:Punto temporal:Suero:Cuantitativo:Prueba de neutralización
fr-FR	French (France)	Coxsackievirus B1 Ac neutralisant:Titre:Ponctuel:Sérum:Semi-Quantitatif:Neutralisation
fr-CA	French (Canada)	Coxsackievirus B1 Ac.neut:Titre:Temps ponctuel:Sérum:SemiQn:Test de neutralisation
it-IT	Italian (Italy)	Coxsackievirus B1 Ab.Neut:Titr:Pt:Siero:SemiQn:Neut Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Siero Test di neutralizzazione Titolo
ko-KR	Korean (Korea, Republic Of)	콕사키바이러스 B1 항체:역가:검사시점:혈청:정량:중화
nl-NL	Dutch (Netherlands)	Coxsackievirus B1 As.neutraliserend:titer:moment:serum:semikwantitatief:neutralisatietest Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Wirus Coxsackie B1 Ab.Neutralizujące:miano:punkt w czasie:surowica:półilościowy:test neutralizacji Synonyms: Przeciwciała do wirusa Coxsackie B1 Przeciwciała neutralizujące do wirusa Coxsackie B1 Wirus Coxsackie Wirus Coxsackie B1
pt-BR	Portuguese (Brazil)	Coxsackie vírus B1 Ac:Título:Pt:Soro:Qn:Teste de neutralização Synonyms: ; CV B1; Coxsackie; Coxsackie virus; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Nt; NT; Neutralization test; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
uk-UA	Ukrainian (Ukraine)	Вірус Коксакі B1 Антитіла.Нейтралізуючі:Титр:МоментЧасу:Сироватка:Кількісно:Нейтралізації тест Synonyms: ABS; Aby; Antby; Anti; Antibodies; Antibody; Autoantibodies; Autoantibody; CAV; Conventional virus neutralization test; Coxsackie; Coxsackie virus; CV; CV B1; cVNT; Dilution factor; Dilution Factor (Titer); ID; Infectious Disease; InfectiousDisease; Microbiology; NAb; NEUTRALIZATION; Neutralization test; NT; Point in time; QNT; Quan; Quant; Quantitative; Random; Serum; Serum virus neutralization; SR; SVN; Titer; Titered; Titre; Ttr; Virus neutralization test; VNT
zh-CN	Chinese (China)	柯萨奇病毒 B1 型抗体.中和:滴定度:时间点:血清:半定量型:中和试验 Synonyms: Ab;自身抗体 Coxsackie;CV;柯萨基病毒;考克塞基病毒 CV B1 Ab CV B1 型 Ab CV B1 型抗体 CV B1 抗体 CV B1;CV B1 型;柯萨基病毒 B1 型;考克塞基病毒 B1 型中和试验;中和抗体;中和微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数时刻;随机;随意;瞬间柯萨基病毒 B1 型 Ab 柯萨基病毒 B1 型抗体柯萨奇病毒 B1 型 Ab 考克塞基病毒 B1 型 Ab 考克塞基病毒 B1 型抗体

Example Units

Unit	Source
titer	REGENSTRIEF
{titer}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.