Version 2.78

Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Fully-Specified Name

Component
Cytomegalovirus Ab
Property
Titr
Time
Pt
System
Ser/Plas
Scale
SemiQn
Method
LA

Additional Names

Short Name
CMV Ab Titr SerPl LA
Display Name
CMV Ab LA [Titer]
Consumer Name Alpha Get Info
Cytomegalovirus (CMV) antibody, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.75
Change Reason
Updated System from Ser to Ser/Plas since this test can also be performed on plasma.
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
54037-7 HEDIS 2009 panel
57820-3 HEDIS 2010 panel
60442-1 HEDIS 2011 panel
67767-4 HEDIS 2012 panel
72199-3 HEDIS 2013 panel
74234-6 HEDIS 2014 Value Sets
75868-0 HEDIS 2015 Value Sets
79544-3 HEDIS 2016 Value Sets
82955-6 HEDIS 2017 Value Sets
87625-0 HEDIS 2018 Value Sets
90766-7 HEDIS 2019 Value Sets

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Cytomegalie-Virus Ak:Titer:Zeitpunkt:Serum oder Plasma:Semiquantitativ:Latexagglutination
Synonyms: CMV
es-AR Spanish (Argentina) [anticuerpo anti - ] citomegalovirus [Ac]:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:aglutinación de látex
es-ES Spanish (Spain) Citomegalovirus Anticuerpos:Titulo / Factor de dilución:Punto temporal:Suero o Plasma:Semicuantitativo:Aglutinación de latex
Synonyms: Semicuantitativo
es-MX Spanish (Mexico) Citomegalovirus Ab:Título:Punto temporal:Suero o Plasma:Cuantitativo:Aglutinación de látex
fr-FR French (France) Cytomégalovirus Ac:Titre:Ponctuel:Sérum/Plasma:Semi-Quantitatif:Agglutination latex
fr-CA French (Canada) Cytomégalovirus, Ac:Titre:Temps ponctuel:Sérum/Plasma:SemiQn:Agglutination au latex
it-IT Italian (Italy) Citomegalovirus Ab:Titr:Pt:Siero/Plasma:SemiQn:LA
Synonyms: Agglutinazione al lattice anticorpo Microbiologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma Titolo
ko-KR Korean (Korea, Republic Of) 거대세포바이러스 항체:역가:검사시점:혈청:정량:라텍스 응집
nl-NL Dutch (Netherlands) Cytomegalovirus As:titer:moment:serum of plasma:semikwantitatief:latexagglutinatie
Synonyms: antistof; antilichaam LA
pl-PL Polish (Poland) Wirus cytomegalii Ab:miano:punkt w czasie:surowica lub osocze:półilościowy:aglutynacja lateksowa
Synonyms: Cytomegalowirus Przecwciała do cytomegalowirusa
pt-BR Portuguese (Brazil) Citomegalovírus Ac:Título:Pt:Soro:Qn:Aglutinação em látex
Synonyms: ; CMV; Cytomgal; Cytomegalo virus; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Latex agglutination; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
zh-CN Chinese (China) 巨细胞病毒 抗体:滴定度:时间点:血清/血浆:半定量型:胶乳凝集试验法
Synonyms: Ab;自身抗体 CMV Ab CMV 抗体 CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒 乳胶凝集试验;凝集试验.胶乳;凝集试验法.胶乳;胶乳凝集试验;胶乳颗粒凝集;胶乳颗粒凝集法;胶乳颗粒凝集试验;胶乳颗粒凝集试验法;颗粒凝集.胶乳;颗粒凝集法.胶乳;颗粒凝集试验.胶乳;颗粒凝集试验法.胶乳 巨细胞病毒 Ab 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 血清或血浆

Example Units

Unit Source
{titer} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=5121-9