5148-2

Echovirus neutralizing antibody [Titer] in Serum by Neutralization test

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Part Descriptions

LP18949-5 Echovirus
An echovirus is a type of RNA virus that belongs to the genus Enterovirus of the Picornaviridae family. Echoviruses are found in the gastrointestinal tract (hence it being part of the enterovirus genus) and exposure to the virus causes other opportunistic infections and diseases. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Echovirus

LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Echovirus Ab.Neut:Titr:Pt:Ser:SemiQn:Neut
Long Common Name: Echovirus neutralizing antibody [Titer] in Serum by Neutralization test
Short Name: ECV NAb Titr Ser Nt
Display Name: Echovirus neut ab Neut test (S) [Titer]
Consumer Name Alpha Get Info: Echovirus neutralizing antibody, Blood

Part Model Get Info

Component
Echovirus Ab.Neut
LP442519-7
- Analyte
  Echovirus Ab.Neut
  LP442519-7
  - Component Numerator
    Echovirus Ab.Neut
    LP442519-7
    - Component Numerator Core
      Echovirus
      LP18949-5
    - Component Numerator Core Suffix
      Ab.Neut
      LP207365-0
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Titr
LP6881-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
SemiQn
LP436123-6
Method
Neut
LP6416-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 1.0
Last Updated: Version 2.78 (NAM)
Change Reason: Release 2.78: COMPONENT: Maintenance ; Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Echovirus Ab.neutralizační:Arbitrární koncentrace (titr):Časový bod:Sérum:Semikvantitativní:Neutralizační test
de-DE	German (Germany)	Echovirus Ak.neutralisierend:Titer:Zeitpunkt:Serum:Semiquantitativ:Neutralisationstest
el-GR	Greek (Greece)	Ιός Echo Ab.Neut:Titr:Pt:Ορός:Ημιποσοτική:Ουδετερόφιλα Synonyms: Ab.Neut MICRO Pt Titr Αντίσωμα Ημιποσοτική Ιός Echo Ορός Ουδετερόφιλα
es-AR	Spanish (Argentina)	[anticuerpo anti - ] virus ECHO [Ac] sin otra especificación:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:neutralización
es-ES	Spanish (Spain)	Echovirus Anticuerpos antineutrófilos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:Prueba de neutralización Synonyms: Semicuantitativo
es-MX	Spanish (Mexico)	Echovirus NOS Ab:Título:Punto temporal:Suero:Cuantitativo:Prueba de neutralización
fr-FR	French (France)	Échovirus Ac neutralisant:Titre:Ponctuel:Sérum:Semi-Quantitatif:Neutralisation
fr-CA	French (Canada)	Échovirus Ac.neut:Titre:Temps ponctuel:Sérum:SemiQn:Test de neutralisation
it-IT	Italian (Italy)	Echovirus Ab.Neut:Titr:Pt:Siero:SemiQn:Neut Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Siero Test di neutralizzazione Titolo
ko-KR	Korean (Korea, Republic Of)	에코바이러스 달리 명시되지 않은 항체:역가:검사시점:혈청:정량:중화
nl-NL	Dutch (Netherlands)	Echovirus As.neutraliserend:titer:moment:serum:semikwantitatief:neutralisatietest Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Echowirus Ab.Neutralizujące:miano:punkt w czasie:surowica:półilościowy:test neutralizacji Synonyms: Echowirus Przeciwciała do Echowirusa NOS
pt-BR	Portuguese (Brazil)	Echovírus NOS Ac:Título:Pt:Soro:Qn:Teste de neutralização Synonyms: ; Other; ECV NOS; EV; Echo virus; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Nt; NT; Neutralization test; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
zh-CN	Chinese (China)	艾柯病毒抗体.中和:滴定度:时间点:血清:半定量型:中和试验 Synonyms: Ab;自身抗体 Echo;Echo 病毒;ECV;EV;人肠细胞病变孤儿病毒;人肠道孤病毒;人肠道细胞病变孤病毒 ECV Ab ECV 抗体中和试验;中和抗体;中和微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数时刻;随机;随意;瞬间艾柯病毒 Ab

Example Units

Unit	Source
{titer}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.