51664-1
Chikungunya virus RNA [Presence] in Specimen by NAA with probe detection
Active
Part Descriptions
LP21132-3 Chikungunya virus
A species of ALPHAVIRUS causing an acute dengue-like fever.
Source: National Library of Medicine, MeSH 2006
LP21132-3 Chikungunya virus
Chikungunya virus (CHIKV) belongs to the mosquito-borne alphavirus genus, in the family Togaviridae, and was first observed in epidemic form in Africa. Serologically, CHIKV belongs to the Semliki Forest (SF) subgroup of alphaviruses. Infection in humans is characterized by rash, high fever and, its hallmark feature, severe arthritis that can persist for years. CHIKV is a small, spherical, enveloped, positive-strand RNA virus. The virion consists of an envelope and a nucleocapsid. The envelope glycoproteins of alphaviruses are the distinguishing factors for testing. The CHIKV genome encodes for two polyproteins; the non-structural polyprotein consisting of four proteins (nsP1, nsP2, nsP3 and nsP4) and the structural polyprotein consisting of five proteins (Capsid, E3, E2, 6K and E1). CHIKV has spikes on the virion surface that are each formed by three E1-E2 heterodimers, where the E1 glycoproteins mediate fusion and E2 glycoproteins interact with the host receptor. PMID: 20111039
CHIKV can be detected between the first and fourth day of infection (the acute phase) using PCR or virus cultivation, and virus-specific IgM and IgG antibodies can be detected during the 8th to the 10th day of infection. Antibody investigation should be performed using serum samples from the acute and convalescent stage.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Chikungunya virus RNA
- Property
- PrThr
- Time
- Pt
- System
- XXX
- Scale
- Ord
- Method
- Probe.amp.tar
Additional Names
- Short Name
- CHIKV RNA Spec Ql NAA+probe
- Display Name
- CHIKV RNA NAA+probe Ql (Specimen)
- Consumer Name Alpha Get Info
- Chikungunya virus, Specimen
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.24
- Last Updated
- Version 2.69
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG51028-5 | Chikungunya virus |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Chikungunya-Virus RNA: |
| es-ES | Spanish (Spain) | Virus Chikungunya RNA: |
| es-MX | Spanish (Mexico) | ARN del virus Chikungunya: |
| fr-CA | French (Canada) | Virus Chikungunya ARN: |
| fr-FR | French (France) | Chikungunya virus ARN: |
| fr-BE | French (Belgium) | Virus Chikungunya ARN: |
| it-IT | Italian (Italy) | Chikungunya virus RNA: Synonyms: CHIK Microbiologia Presenza o Soglia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA |
| nl-NL | Dutch (Netherlands) | Chikungunya-virus RNA: Synonyms: probe.amp.tar |
| pt-BR | Portuguese (Brazil) | Chikungunya vírus Ac: Synonyms: Ribonucleic acid; |
| ru-RU | Russian (Russian Federation) | Чикунгунья вирус РНК: Synonyms: ДНК проба; |
| tr-TR | Turkish (Turkey) | Chikungunya virus RNA: Synonyms: Mevcut |
| zh-CN | Chinese (China) | 基孔肯亚病毒 RNA: Synonyms: 不明的; |
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