51771-4

Histoplasma capsulatum DNA [#/volume] in Specimen by NAA with probe detection

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Part Description

LP16650-1 Histoplasma capsulatum
Histoplasmosis capsulatum is a dimorphic fungal pathogen with filamentous or yeast forms,depending on nutritional factors and temperature.The M antigen is a well-known glycoprotein used as a diagnostic antigen for acute histoplasmosis as it induces the first precipitins during disease. Monoclonal antibodies (mAbs) to the M antigen have been found to modify the pathogenesis of histoplasmosis.Given the shortcomings of current therapies, the administration of mAbs is being investigated. PMID: 22347215 The H band is less commonly seen than the M band and is indicative of chronic or severe acute infections with H capsulatum.

H. capsulatum is found in nature primarily as a saprophytic mold. The mold form is comprised of hyaline septate hyphae, which produce two different asexual reproduction structures, macroconidia and microconidia. The micronidia are believed to be responsible for disease propagation since their 2-6 µm size is well suited for disposition into the distal alveoli. Infection is typically acquired through inhalation of fungal propagules upon disturbances of contaminated soil or excreta. Environmental and genetic factors influence disease manifestations which can range from asymptomatic or mild influenza-like disease to a disseminated sepsis form. Manifestations depend on the magnitude of exposure, the host's immunological status and the virulence of the infective strain. Reactivation of latent infection can result in significant disease, particularly for immunosuppressed individuals. Despite the availability of potent antifungal drugs, nearly one in ten patients hospitalized with histoplasmosis dies. PMID: 17223625 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Histoplasma capsulatum DNA:NCnc:Pt:XXX:Qn:Probe.amp.tar
Long Common Name: Histoplasma capsulatum DNA [#/volume] in Specimen by NAA with probe detection
Short Name: H capsul DNA # Spec NAA+probe
Display Name: H. capsulatum DNA NAA+probe (Specimen) [#/Vol]
Consumer Name Alpha Get Info: Histoplasma capsulatum, Specimen

Part Model Get Info

Component
Histoplasma capsulatum DNA
LP38410-4
- Analyte
  Histoplasma capsulatum DNA
  LP38410-4
  - Component Numerator
    Histoplasma capsulatum DNA
    LP38410-4
    - Component Numerator Core
      Histoplasma capsulatum
      LP16650-1
    - Component Numerator Core Suffix
      DNA
      LP32416-7
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
NCnc
LP6836-3
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
XXX
LP7735-6
- System Core
  XXX
  LP7735-6
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Probe.amp.tar
LP6464-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.24
Last Updated: Version 2.70 (MIN)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Histoplasma capsulatum DNA:Početní koncentrace:Časový bod:XXX:Kvantitativní:Amplifikace nukleových kyselin s detekcí sondou
el-GR	Greek (Greece)	Histoplasma capsulatum (Ιστόπλασμα) DNA:NCnc:Pt:XXX:Qn:Ανιχνευτής.ενίσχυση.στόχου Synonyms: DNA Histoplasma capsulatum (Ιστόπλασμα) MICRO NCnc Pt Qn XXX Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου
es-ES	Spanish (Spain)	Histoplasma capsulatum ADN:Concentración de número:Punto temporal:XXX:Qn:Sonda con amplificación dirigida Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	ADN de Histoplasma capsulatum:Concentración numérica:Punto temporal:XXX:Cuantitativo:Amplificación de ácidos nucleicos con detección de sonda
fr-CA	French (Canada)	Histoplasma capsulatum, ADN:Concentration numérique:Temps ponctuel:XXX:Quantitatif:Sonde avec amplification de la cible
fr-FR	French (France)	Histoplasma capsulatum ADN:Nombre/Volume:Ponctuel:Milieux divers:Numérique:PCR amplification de cible
fr-BE	French (Belgium)	Histoplasma capsulatum ADN:Concentration numérique:Temps ponctuel:XXX:Quantitatif:Sonde avec amplification de la cible
it-IT	Italian (Italy)	Histoplasma capsulatum DNA:NCnc:Pt:XXX:Qn:Sonda.amp.tar Synonyms: Concentrazione Numerica Microbiologia Punto nel tempo (episodio) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL	Dutch (Netherlands)	Histoplasma capsulatum DNA:aantal/volume:moment:XXX:kwantitatief:probe-detectie Synonyms: probe.amp.tar
pt-BR	Portuguese (Brazil)	Histoplasma capsulatum DNA:NCnc:Pt:XXX:Qn:Sonda com limite de detecção da amplificação de alvo Synonyms: ; H capsul; H capsulatum; H farciminosum; Histoplasma farciminosum; Deoxyribonucleic acid; #; Number concentration; Count/mass; Count; AcS; CT; Acsolute; Acsolutes; Cnt; Point in time; Random; Misc; Miscellaneous; Unspecified; Other; Quantitative; QNT; Quant; Quan; PCR; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Amplified; Histo; Histopl; Histoplasmos; Histoplasmosis; Microbiology; Viral load
ru-RU	Russian (Russian Federation)	Histoplasma capsulatum ДНК:КолОб:ТчкВрм:XXX:Колич:Проба.усил.миш Synonyms: ДНК проба;ДНК зонд Количественный Количество в объеме Проба с мишени усилением Точка во времени;Момент
tr-TR	Turkish (Turkey)	Histoplazma Kapsulatum DNA:SayKons:Zmlı:XXX:Kant:Prob.amf.hdf
zh-CN	Chinese (China)	荚膜组织胞浆菌 DNA:计数型浓度:时间点:XXX:定量型:探针法.基因扩增.靶向 Synonyms: 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项借助扩增的探针方法;借助扩增的探针法;探针法.扩增借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向单位体积内的数量或计数;数量型浓度(单位体积);数量或计数型浓度(计数/体积);数量或计数型浓度(单位体积);计数型浓度(单位体积) 去氧核糖核酸;脱氧核糖核酸去氧核糖核酸;脱氧核糖核酸;脱氧核糖核酸（Deoxyribonucleic acid，DNA）可用数量表示的;定量性;数值型;数量型;连续数值型标尺微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）扩增型扩增性数量型浓度探针法.基因扩增.靶向数量型浓度探针法.扩增.靶向数量或计数型浓度探针法.扩增.靶向时刻;随机;随意;瞬间病毒负荷病毒负荷量病毒负载病毒载量病毒载量（Viral load）皮疽组织胞浆菌 DNA 皮疽组织胞浆菌;美洲型组织胞浆菌;鼻疽性组织浆菌组织胞浆菌属组织胞浆菌病经过扩增的美洲型组织胞浆菌 DNA 脱氧核糖核酸探针计数型浓度探针法.基因扩增.靶向计数型浓度探针法.扩增.靶向鼻疽性组织浆菌 DNA

Example Units

Unit	Source
{copies}/mL	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.