Version 2.77

Part Description

LP16714-5   Histone
Histones are small nuclear proteins that together with dsDNA, represent a nucleosome, the structural unit of chromatin. Anti-histone antibodies are associated with various autoimmune diseases, including systemic lupus erythematosus (SLE), rheumatoid arthritis, Sjogren's syndrome, systemic sclerosis, infectious diseases (including HIV), and some neurological disorders such as Alzheimer's disease and dementia. Nearly all patients with drug-induced SLE have anti-histone antibodies, but they are also present in patients with idiopathic forms of the disease. One study showed a correlation between SLE with positive anti-dsDNA, anti-nucleosome and anti-histone antibodies and renal disease, including proliferative glomerulonephritis. PMID: 24649358 Source: Regenstrief LOINC, PMID: 24649358

Fully-Specified Name

Component
Histone Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IF

Additional Names

Short Name
Histone Ab Ser Ql IF
Display Name
Histone Ab IF Ql (S)
Consumer Name Alpha Get Info
Histone antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG21281-7 Histone Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Histon Ak:Nachweis oder Schwellenwert:Zeitpunkt:Serum:Ordinal:Immunfluoreszenztest
es-AR Spanish (Argentina) [anticuerpo anti - ] histona [Ac]:concentración arbitraria:punto en el tiempo:suero:ordinal:inmunofluorescencia
es-ES Spanish (Spain) Histona Anticuerpos:PrThr:Punto temporal:Suero:Ord:Inmunofluorescencia (IF)
es-MX Spanish (Mexico) Histona Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunofluorescencia (IF)
et-EE Estonian (Estonia) Histoon antikehad:PrThr:Pt:S:Ord:IF
Synonyms: Järgarvuline Juhuslik Seerum
fr-CA French (Canada) Histone , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunofluorescence
fr-FR French (France) Histones anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunofluorescence
fr-BE French (Belgium) Histone Ac:PrThr:Temps ponctuel:Sérum:Ordinal:Immunofluorescence
Synonyms: Anticorps
it-IT Italian (Italy) Istone Ab:PrThr:Pt:Siero:Ord:IF
Synonyms: anticorpo Immunofluorescenza (IF) Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
ko-KR Korean (Korea, Republic Of) 히스톤 항체:임의농도:검사시점:혈청:순위척도:면역형광
nl-NL Dutch (Netherlands) histon As:aanwezigheid:moment:serum:ordinaal:immunofluorescentie
Synonyms: antistof; antilichaam IF
pt-BR Portuguese (Brazil) Histona Ac:ACnc:Pt:Soro:Ord:Imunofluorescência
Synonyms: Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; ACIF; FA; Fluorescent antibody; Immune fluorescence; Fluoresent; Immunoflour; Immunofluor; Immunofluorescence; IFA; Time Resolved Fluorescence; Anticomplement Immunofluorescence; TRF; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
ru-RU Russian (Russian Federation) Гистон Ат:PrThr:ТчкВрм:Сыв:Пор:ИФ
Synonyms: Антитело Иммунофлюоресценция (ИФ) Порядковый Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Histon Ab:MevcEşik:Zmlı:Ser:Srl:IF
Synonyms: Ak İmmünflorerans Mevcut
zh-CN Chinese (China) 组蛋白 抗体:存在情况或阈值:时间点:血清:序数型:免疫荧光法
Synonyms: Ab;自身抗体 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 时刻;随机;随意;瞬间 组朊 组朊 Ab 组朊抗体 组蛋白 Ab 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目(非微生物学);血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验(非微生物学);血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=5217-5