Version 2.78

Part Descriptions

LP18494-2   Activated protein C resistance
A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC) which increases the risk of a clotting disorder. The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance. Source: National Library of Medicine, MeSH 2006

LP18494-2   Activated protein C resistance
Activated protein C resistance (APC) has emerged as the most frequent abnormality in patients with idiopathic thrombosis. Patients found to be heterozygous for APC resistence have a seven fold increased risk for venous thrombosis as compared to the general popualtion. Homozygous individuals have an eight fold increased risk of thrombosis. Familial studies and counselling should be considered for positive patients. The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance. Often measured as the ratio of the Appt W APC. Source: Regenstrief Institute

Fully-Specified Name

Component
Activated protein C resistance
Property
PrThr
Time
Pt
System
PPP
Scale
Ord
Method
Coag

Additional Names

Short Name
aPCR PPP Ql
Display Name
Activated protein C resistance Coag Ql (PPP)
Consumer Name Alpha Get Info
Activated Protein C Resistance, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
COAG
Type
Laboratory
First Released
Version 2.24
Last Updated
Version 2.73
Change Reason
Property changed from Acnc to fit the current LOINC model.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
17429

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: APC-Resistenz (qual.)
de-DE German (Germany) Aktiviertes-Protein-C-Resistenz:Nachweis oder Schwellenwert:Zeitpunkt:Thrombozytenarmes Plasma:Ordinal:Gerinnungstest
Synonyms: APC-Resistenz
es-ES Spanish (Spain) Resistencia a la proteína C activada:PrThr:Punto temporal:Plasma pobre en plaquetas:Ord:Coagulativo
es-MX Spanish (Mexico) Resistencia a la proteína C activada:Presencia o umbral:Punto temporal:Plasma pobre en plaquetas:Ordinal:Ensayo de coagulación
et-EE Estonian (Estonia) Aktiveeritud proteiini C resistentsus:PrThr:Pt:PPP:Ord:Koagulomeetria
Synonyms: Järgarvuline Juhuslik Trombotsüütidevaene plasma
fr-CA French (Canada) Résistance à la protéine C activée:Présence-Seuil:Temps ponctuel:Plasma pauvre en plaquettes:Ordinal:Test de coagulation
fr-FR French (France) Protéine C activée résistance:Présence/Seuil:Ponctuel:Plasma pauvre en plaquettes:Qualitatif:Coagulation
fr-BE French (Belgium) Résistance à la protéine C activée:PrThr:Temps ponctuel:Plasma pauvre en plaquettes:Ordinal:Test de coagulation
Synonyms: RPCa Test d''Hémostase
it-IT Italian (Italy) Proteina C attivata, resistenza:PrThr:Pt:PPP:Ord:Coag
Synonyms: Plasma povero di piastrine Presenza o Soglia Punto nel tempo (episodio) Resistenza alla proteina C attivata Studio di coagulazione Test di coagulazione
nl-NL Dutch (Netherlands) geactiveerd proteïne C-resistentie:aanwezigheid:moment:plaatjesarm plasma:ordinaal:stollingsmethode
Synonyms: coagulatiemethode
pt-BR Portuguese (Brazil) Resistência a proteína C ativada:ACnc:Pt:PPPQ:Ord:Coagulação
Synonyms: ; Prot C; PC; Autoprothrombin II-a; PR; aPCR; APCr; APC-R; Arbitrary concentration; Point in time; Random; Platelet poor plasma; Plas; Ql; Ordinal; QL; Qualitative; Qual; Screen; Coagulation assay; Clot; Tilt tube; ClottAcle; Resistanc; Resist; Resistent; Resistant; APC
ru-RU Russian (Russian Federation) Активированный протеин С резистентность:PrThr:ТчкВрм:ОПП:Пор:Коаг
Synonyms: Анализ факторов свертывания крови;Коагулограмма Белок Белок C Обеднённая пластинками плазма;Бедная тромбоцитами плазма Порядковый Точка во времени;Момент
tr-TR Turkish (Turkey) Aktiflenmiş protein C resistans:MevcEşik:Zmlı:TFkP:Srl:Koag
Synonyms: Mevcut
zh-CN Chinese (China) 活化蛋白 C 抗性:存在情况或阈值:时间点:贫血小板血浆:序数型:凝血功能分析
Synonyms: APC 抗性;APC 抵抗;aPCR;APC-R;活化 C 蛋白抗性;活化蛋白 C 抗性(Activated protein C resistance,APC-R);活化蛋白 C 抗性是采用 APC 的 aPTT 与不采用 APC 的 aPTT 之比。;活化蛋白 C 抵抗;活化蛋白 C 抵抗性 C 型;丙;丙型 C 蛋白;PC;自体凝血因子 II-a;自体凝血素 II-a;自体凝血酶原 II-a;自体前凝血酶 II-a;自体因子 II-a;自体第二凝血因子-a;自体第二因子-a;自身凝血因子 II-a;自身凝血素 II-a;自身凝血酶原 II-a;自身前凝血酶 II-a;自身因子 II-a;自身第二凝血因子-a;自身第二因子-a;蛋白 C(Protein C,PC);蛋白质 C PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 乏血小板血浆;Platelet poor plasma;PPP 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 倾斜试管;倾斜试管法;凝固测定;凝血功能测定;凝血测定;快速凝固试验;快速凝血试验;快速凝集试验 凝血功能;凝血功能试验;凝血过程;血液凝固;血液凝固功能;血液凝固过程 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 抗力 抗耐性 抵抗力 抵抗性 时刻;随机;随意;瞬间 活化型蛋白C(Activated protein C,APC) 激活型蛋白C 激活型蛋白C(Activated protein C,APC) 电阻 耐性 阻力

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=52750-7