Version 2.78

Part Description

LP14853-3   Varicella zoster virus
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.[http://jvi.asm.org/content/88/24/13936.full] In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.[https://grose.lab.uiowa.edu/vzv-genomes-and-evolution] Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/ Source: Regenstrief LOINC

Fully-Specified Name

Component
Varicella zoster virus Ab
Property
ACnc
Time
Pt
System
Ser
Scale
Qn
Method
Comp fix

Additional Names

Short Name
VZV Ab Ser CF-aCnc
Display Name
VZV Ab CF Qn (S)
Consumer Name Alpha Get Info
Varicella zoster virus (VZV; Chickenpox) antibody, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.24
Last Updated
Version 2.69
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG32750-8 Varicella zoster virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Varicella-Zoster-Virus Ak:Arbiträre Konzentration:Zeitpunkt:Serum:Quantitativ:Komplementbindungsreaktion
Synonyms: Human alphaherpesvirus 3; VZV
es-ES Spanish (Spain) Virus Varicella zoster Anticuerpos:Concentración arbitraria:Punto temporal:Suero:Qn:Fijación del complemento
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Virus de varicela zóster Ab:Concentración arbitraria:Punto temporal:Suero:Cuantitativo:Fijación del complemento
fr-CA French (Canada) Virus varicelle-zona, Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:Fixation du complément
fr-FR French (France) Varicelle zona virus Ac:Arbitraire/Volume:Ponctuel:Sérum:Numérique:Fixation du complément
fr-BE French (Belgium) Virus varicelle-zona Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:Fixation du complément
Synonyms: Anticorps VZV
it-IT Italian (Italy) Varicella zoster, virus Ab:ACnc:Pt:Siero:Qn:Fissazione complemento
Synonyms: anticorpo Concentrazione Arbitraria Fissazione del complemento Microbiologia Punto nel tempo (episodio) Siero Virus della varicella zoster
nl-NL Dutch (Netherlands) varicella-zostervirus As:eenheid/volume:moment:serum:kwantitatief:complementfixatie
Synonyms: antistof; antilichaam Varicella zoster virus
pt-BR Portuguese (Brazil) Varicella zoster vírus Ac:ACnc:Pt:Soro:Qn:Fixação do complemento
Synonyms: ; VZV; Shingles; Chicken pox; Human herpesvirus 3; HHV-3; Chickenpox; Herpes zoster; VZ; Chicken pox virus; Arbitrary concentration; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; CF; Complement fixation; Compfix; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
ru-RU Russian (Russian Federation) Varicella zoster вирус Ат:ПроизвКонц:ТчкВрм:Сыв:Колич:Компл фикс
Synonyms: Антитело Количественный Комплемента фиксация Произвольная концентрация Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Varicella zoster virüsü Ab:SçKons:Zmlı:Ser:Kant:Komp fiks
Synonyms: Ak Kompleman fiksasyon
zh-CN Chinese (China) 水痘带状疱疹病毒 抗体:任意型浓度:时间点:血清:定量型:补体结合试验
Synonyms: Ab;自身抗体 HHV-3 Ab HHV-3 抗体 HHV-3;VZ;VZV;人类疱疹病毒 3 型;人类疱疹病毒 III 型;带状疱疹;水痘;水痘带状疱疹;水痘病毒;Varicella zoster virus;水痘-带状疱疹病毒 VZV Ab VZV 抗体 人类疱疹病毒 3 型 Ab 人类疱疹病毒 3 型抗体 人类疱疹病毒 III 型 Ab 人类疱疹病毒 III 型抗体 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 水痘带状疱疹病毒 Ab 水痘病毒 Ab 水痘病毒抗体 补体固定;补体固定试验;补体结合;补体结合反应

Example Units

Unit Source
[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=52978-4