53448-7

Cycloguanil [Mass/volume] in Serum or Plasma

Active

Part Description

LP70434-3 Cycloguanil
Cycloguanil is a dihydrofolate reductase inhibitor, and is a metabolite of the antimalarial drug proguanil; its formation in vivo has been thought to be primarily responsible for the antimalarial activity of proguanil. However, more recent work has indicated that, while proguanil is synergistic with the drug atovaquone (as in the combination Malarone), cycloguanil is in fact antagonistic to the effects of atovaquone, suggesting that, unlike cycloguanil, proguanil may have an alternative mechanism of antimalarial action besides dihydrofolate reductase inhibition.

Although cycloguanil is not currently in general use as an antimalarial, the continuing development of resistance to current antimalarial drugs has led to renewed interest in studying the use of cycloguanil in combination with other drugs Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LOINC Names Get Info

Fully-Specified Name: Cycloguanil:MCnc:Pt:Ser/Plas:Qn:
Long Common Name: Cycloguanil [Mass/volume] in Serum or Plasma
Short Name: Cycloguanil SerPl-mCnc
Display Name: Cycloguanil [Mass/Vol]
Consumer Name Alpha Get Info: Cycloguanil, Blood

Part Model Get Info

Component
Cycloguanil
LP70434-3
- Analyte
  Cycloguanil
  LP70434-3
  - Component Numerator
    Cycloguanil
    LP70434-3
    - Component Numerator Core
      Cycloguanil
      LP70434-3
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.26
Last Updated: Version 2.70 (MIN)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Cykloguanil:Hmotnostní koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GR	Greek (Greece)	Κυκλογουανίλη:MCnc:Pt:Ορός/Πλάσμα:Qn: Synonyms: DRUG/TOX MCnc Pt Qn Κυκλογουανίλη Ορός Ορός/Πλάσμα Πλάσμα
es-ES	Spanish (Spain)	Cicloguanilo:Concentración de masa:Punto temporal:Suero o Plasma:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Cicloguanil:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE	Estonian (Estonia)	Tsükloguaniil:MCnc:Pt:S/P:Qn: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-FR	French (France)	Cycloguanil:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE	French (Belgium)	Cycloguanil:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT	Italian (Italy)	Cicloguanile:MCnc:Pt:Siero/Plasma:Qn: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL	Dutch (Netherlands)	cycloguanil:massa/volume:moment:serum of plasma:kwantitatief:
pl-PL	Polish (Poland)	Cykloguanil:stężenie masowe:punkt w czasie:surowica lub osocze:ilościowy:
pt-BR	Portuguese (Brazil)	Cicloguanil:MCnc:Pt:Sor/Plas:Qn: Synonyms: Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU	Russian (Russian Federation)	Циклогуанил:МассКонц:ТчкВрм:Сыв/Плаз:Колич: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Sikloguanil:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN	Chinese (China)	氯胍三嗪:质量浓度:时间点:血清/血浆:定量型: Synonyms: Cycloguanil;CG;环氯胍;抗疟药可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间毒品毒品类水平;浓度;质量浓度(单位体积) 药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类血清或血浆

Example Units

Unit	Source
mg/L	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.