LOINC
Version 2.73

53828-0cycloSPORINE [Mass/volume] in Blood --troughActive

Part Descriptions

LP16098-3   cycloSPORINE
Cyclosporine (Brand names Neoral, Restasis, Sandimmune, Gengraf) is a cyclic undecapeptide of fungal origin and a potent calcineurin inhibitor immunosuppressive agent. The introduction of cyclosporine in human organ transplantation substantially improved patient and graft survival in patients receiving heart, kidney, liver, pancreas, lung or bone marrow transplants. Cyclosporine was the first drug to specifically and reversibly inhibit the activation and proliferation of lymphocytes. The main mechanism through which cyclosporine exerts its immunosuppressive effect is the inhibition of T cell activation and proliferation. Monitoring and concentration-controlled dosing is required to maintain patient drug levels within a narrow therapeutic window; low levels could cause transplant rejection and high levels may cause nephrotoxicity. [PMID:19545653] Source: Regenstrief LOINC, PMID: 19545653

LP20176-1   trough
In medicine, a trough level is the lowest level that a medicine is present in the body. In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. It should be contrasted with a "peak level", which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It helps in therapeutic drug monitoring. It is widely used in clinical trials for newer medicines for its therapeutic effectiveness and safety. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Trough levels for therapeutic drug monitoring

Fully-Specified Name

Component
cycloSPORINE^trough
Property
MCnc
Time
Pt
System
Bld
Scale
Qn
Method

Additional Names

Short Name
cycloSPORINE Trough Bld-mCnc
Display Name
cycloSPORINE trough (Bld) [Mass/Vol]
Consumer Name Alpha
cycloSPORINE trough, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.26
Last Updated
Version 2.73
Order vs. Observation
Both
Common US Lab Results Rank
6515

Member of these Groups

LG19342-1 Cyclosporine^trough|MCnc|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
环孢菌素^波谷:质量浓度:时间点:全血:定量型:
nl-NLDutch (Netherlands)
cyclosporine^dalspiegel:massa/volume:moment:bloed:kwantitatief:
et-EEEstonian (Estonia)
Tsüklosporiin^baas:MCnc:Pt:B:Qn:
fr-BEFrench (Belgium)
Cyclosporine^Creux:Concentration de masse:Temps ponctuel:Sang:Quantitatif:
fr-CAFrench (Canada)
Cyclosporine^Creux:Concentration de masse:Temps ponctuel:Sang:Quantitatif:
fr-FRFrench (France)
Ciclosporine taux résiduel:Masse/Volume:Ponctuel:Sang:Numérique:
el-GRGreek (Greece)
Κυκλοσπορίνη^κατώτερα επίπεδα:Συγκέντρωση μάζας:Χρονική στιγμή:Αίμα:Ποσοτική:
it-ITItalian (Italy)
Ciclosporina^valore minimo:MCnc:Pt:Sangue:Qn:
pt-BRPortuguese (Brazil)
Ciclosporina^basal:MCnc:Pt:SgTotal:Qn:
ru-RURussian (Russian Federation)
Циклоспорин^остаточная концентрация:МассКонц:ТчкВрм:Кр:Колич:
es-MXSpanish (Mexico)
cicloesporino ^ canal:Concentración de masa:Punto temporal:Sangre:Cuantitativo:
es-ESSpanish (Spain)
Ciclosporina^Valle monitorización terapéutica de fármacos:Concentración de masa:Punto temporal:Sangre:Qn:
tr-TRTurkish (Turkey)
Siklosporin^en düşük:KütlKons:Zmlı:Kan:Kant:

Example Units

Unit Source
ug/L Example UCUM Units
ng/mL REGENSTRIEF

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=53828-0