LOINC
Version 2.67

53979-1Actin Ab [Presence] in Serum or Plasma by ImmunofluorescenceActive

Part Descriptions

LP14639-6   Actin
Actin is a protein found in all eukaryotic cells. It is the monomeric subunit of two types of filaments in cells: microfilaments and thin filaments. There are three main groups of actin isoforms - alpha, beta, and gamma. The alpha actins are found in muscle tissues and contribute to muscle contraction. The beta and gamma actins exist in most cell types as components of the cytoskeleton and contribute to cell shape, motility and division. Actin is primarily measured to determine the effects of proteins and drugs on actin polymerization and depolymerization and has been shown to be a host factor for HIV-1 infection. [NCBI Books:NBK9908] Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, Wikipedia

LP36959-2   Actin Ab
Anti-actin antibodies are found at increased frequency in certain autoimmune diseases and may be of some diagnostic value.

In coeliac disease anti-actin antibodies correlated with the level of intestinal damage.

In autoimmune hepatitis anti-actin antibodies correlate with patterns of immune recognition, the pattern of recognition was specific to a small percentage of auto-immune hepatitis type 1 or cryptogenic hepatitis patients.

In gastric cancer anti-actin antibodies were elevated, along with other antibodies in severe disease with poor outcomes. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Fully-Specified Name

Component
Actin Ab
Property
PrThr
Time
Pt
System
Ser/Plas
Scale
Ord
Method
IF

Additional Names

Short Name
Actin Ab SerPl Ql IF
Display Name
Actin Ab IF Ql

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.26
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Language Variants Get Info

zh-CNChinese (CHINA)
肌动蛋白 抗体:存在情况或阈值:时间点:血清/血浆:序数型:免疫荧光法
nl-NLDutch (NETHERLANDS)
actine As:aanwezigheid:moment:serum of plasma:ordinaal:immunofluorescentie
et-EEEstonian (ESTONIA)
Aktiin antikehad:PrThr:Pt:S/P:Ord:IF
fr-BEFrench (BELGIUM)
Actine Ac:PrThr:Temps ponctuel:Sérum/Plasma:Ordinal:Immunofluorescence
fr-CAFrench (CANADA)
Actine , Ac:Présence-Seuil:Temps ponctuel:Sérum/Plasma:Ordinal:Immunofluorescence
fr-FRFrench (FRANCE)
Actine anticorps:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:Immunofluorescence
de-ATGerman (AUSTRIA)
Aktin-AK ql.IF
de-DEGerman (GERMANY)
Aktin Ak:AKnz:Pkt:Ser/Plas:Ord:IF
it-ITItalian (ITALY)
Actina , Ab:PrThr:Pt:Siero/Plasma:Ord:IF
pt-BRPortuguese (BRAZIL)
Actina Ac:ACnc:Pt:Sor/Plas:Ord:Imunofluorescência
ru-RURussian (RUSSIAN FEDERATION)
Актин Ат:PrThr:ТчкВрм:Сыв/Плаз:Пор:ИФ
es-ESSpanish (SPAIN)
Actina Anticuerpos:PrThr:Punto temporal:Suero o Plasma:Ord:Inmunofluorescencia (IF)
tr-TRTurkish (TURKEY)
Aktin Ab:MevcEşik:Zmlı:Ser/Plaz:Srl:IF

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=53979-1