Version 2.76

Part Description

LP14853-3   Varicella zoster virus
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.[http://jvi.asm.org/content/88/24/13936.full] In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.[https://grose.lab.uiowa.edu/vzv-genomes-and-evolution] Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/ Source: Regenstrief LOINC

Fully-Specified Name

Component
Varicella zoster virus Ab
Property
Titr
Time
Pt
System
Ser
Scale
SemiQn
Method
Comp fix

Additional Names

Short Name
VZV Ab Titr Ser CF
Display Name
VZV Ab CF (S) [Titer]
Consumer Name Alpha Get Info
Varicella zoster virus (VZV; Chickenpox) antibody, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.75
Order vs. Observation
Both
Common Test Rank Get Info
12135

Member of these Groups Get Info

LOINC Group Group Name
LG32750-8 Varicella zoster virus

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: VZV-AK Ti. KBR
de-DE German (Germany) Varicella-Zoster-Virus Ak:Titer:Zeitpunkt:Serum:Semiquantitativ:Komplementbindungsreaktion
Synonyms: Human alphaherpesvirus 3; VZV
es-AR Spanish (Argentina) anticuerpo contra virus Varicela-zoster:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:fijación del complemento
es-ES Spanish (Spain) Virus Varicella zoster Anticuerpos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:Fijación del complemento
Synonyms: Semicuantitativo
es-MX Spanish (Mexico) Virus de varicela zóster Ab:Título:Punto temporal:Suero:Cuantitativo:Fijación del complemento
fr-CA French (Canada) Virus varicelle-zona , Ac:Titre:Temps ponctuel:Sérum:Semi-Quantitatif:Fixation du complément
fr-FR French (France) Varicelle zona virus Ac:Titre:Ponctuel:Sérum:Semi-Quantitatif:Fixation du complément
it-IT Italian (Italy) Varicella zoster, virus Ab:Titr:Pt:Siero:SemiQn:Fissazione complemento
Synonyms: anticorpo Fissazione del complemento Microbiologia Punto nel tempo (episodio) Siero Titolo Virus della varicella zoster
ko-KR Korean (Korea, Republic Of) 수두 대상포진 바이러스 항체:역가:검사시점:혈청:정량:보체결합반응
nl-NL Dutch (Netherlands) varicella-zostervirus As:titer:moment:serum:semikwantitatief:complementfixatie
Synonyms: antistof; antilichaam Varicella zoster virus
pt-BR Portuguese (Brazil) Varicella zoster vírus Ac:Título:Pt:Soro:Qn:Fixação do complemento
Synonyms: ; VZV; Shingles; Chicken pox; Human herpesvirus 3; HHV-3; Chickenpox; Herpes zoster; VZ; Chicken pox virus; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; CF; Complement fixation; Compfix; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
zh-CN Chinese (China) 水痘带状疱疹病毒 抗体:滴定度:时间点:血清:半定量型:补体结合试验
Synonyms: Ab;自身抗体 HHV-3 Ab HHV-3 抗体 HHV-3;VZ;VZV;人类疱疹病毒 3 型;人类疱疹病毒 III 型;带状疱疹;水痘;水痘带状疱疹;水痘病毒;Varicella zoster virus;水痘-带状疱疹病毒 VZV Ab VZV 抗体 人类疱疹病毒 3 型 Ab 人类疱疹病毒 3 型抗体 人类疱疹病毒 III 型 Ab 人类疱疹病毒 III 型抗体 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 水痘带状疱疹病毒 Ab 水痘病毒 Ab 水痘病毒抗体 补体固定;补体固定试验;补体结合;补体结合反应

Example Units

Unit Source
titer REGENSTRIEF
{titer} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=5401-5