5475-9
Deprecated CD40 cells/100 cells in Blood
Deprecated
Status Information
- Status
- DEPRECATED
- Reason
- Duplicate
| Map-To | Long Common Name | Mapping Guidance |
|---|---|---|
| 17147-0 | CD40 cells/cells in Blood |
Part Description
LP20077-1 CD40
CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
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Source: Wikipedia,
CD40
LOINC Names Get Info
- Fully-Specified Name
- CD40:
ACnc: Pt: WBC: Qn: - Long Common Name
- Deprecated CD40 cells/100 cells in Blood
- Short Name
- Deprecated CD40 WBC-aCnc
- Display Name
- CD40 Qn (WBC)
- Consumer Name Alpha Get Info
- CD40, White blood cells
Part Model Get Info
Basic Attributes
- Class
- CELLMARK
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.69 (MIN)
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | CD40: |
| el-GR | Greek (Greece) | CD40: Synonyms: ACnc CD40 CELLMARK Pt Qn Αριθμός λευκών αιμοσφαιρίων |
| es-AR | Spanish (Argentina) | CD40: |
| es-ES | Spanish (Spain) | CD40: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | CD40: |
| it-IT | Italian (Italy) | CD40: Synonyms: Concentrazione Arbitraria Globuli bianchi Modelli di superficie cellulare Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | CD40: Synonyms: witte bloedcellen |
| pl-PL | Polish (Poland) | CD40: Synonyms: CD40 |
| pt-BR | Portuguese (Brazil) | CD40: Synonyms: Bp50; |
| ru-RU | Russian (Russian Federation) | CD40: Synonyms: Количественный Произвольная концентрация Точка во времени; |
| tr-TR | Turkish (Turkey) | CD40: Synonyms: WBC |
| zh-CN | Chinese (China) | CD40: Synonyms: Bp50 WBC; |
Example Units
| Unit | Source |
|---|---|
| [arb'U]/mL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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LOINC Copyright
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